Omalirel 150mg Injection

Introduction:

Omalirel 150mg Injection contains the active constituent omalizumab. It is used to prevent asthma from getting worse by controlling symptoms of severe allergic asthma in adults and children above 6 years of age. It is used to treat chronic rhino sinusitis (inflammation of the nose and sinuses) with nasal polyps (small growths on the lining of the nose) and chronic spontaneous urticaria (CSU). Talk to your doctor if you have kidney disorders, liver disorders, allergic conditions, autoimmune disorder (disease in which your own immune system attacks parts of your body) or you are travelling to a region where parasitic infections are common before taking this medicine. Contact your doctor if your experience any allergic reactions while taking this medicine.

Uses of Omalirel 150mg Injection:

• Allergic asthma
• Chronic rhino sinusitis with nasal polyps
• Chronic spontaneous urticaria (CSU)

How Omalirel 150mg Injection works:

Omalirel 150mg Injection works by blocking a substance called immunoglobulin E (IgE) in the the body. IgE plays a key role in causing allergic asthma, chronic rhino sinusitis with nasal polyps and CSU.

Interactions with other drugs:

Inform your doctor about any medications you are taking before starting treatment with Omalirel 150mg Injection.

More information:

• Keep this medicine out of the sight and reach of children. 
• Store in a refrigerator between 2°C to 8°C. Do not freeze.

References:

1. Novartis Pharmaceuticals Corp; Electronic Medicines Compendium; [Revised: July 2020] [Accessed:25/Apr/2021], https://www.medicines.org.uk/emc/files/pil.4725.pdf
2. Genentech USA, Novartis Pharmaceuticals Corp; US Food and Drug Administration; [Revised: July 2016] [Accessed:25/Apr/2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/103976s5225lbl.pdf
3. C Kumar et al; Omalizumab; NCBI Bookshelf; [Revised: Sept 2020] [Accessed:25/Apr/2021], https://www.ncbi.nlm.nih.gov/books/NBK545183/
4. K Godse et al; Omalizumab: A review; International Journal of Dermatology 2015; [Accessed:25/Apr/2021], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533538/
5. KD Tripathi, Essentials of Medical Pharmacology, Drugs for cough and bronchial asthma, 7th edition, 2013, 231.

How to use Omalirel 150mg Injection:

It will be given to you by your health care professional.

Safety advice:

Pregnancy:

This medicine is not safe to be used in pregnancy. Consult with your doctor for advice.

Breastfeeding:

It is not recommended to breastfeed while taking Omalirel 150mg Injection. Consult with your doctor for advice.

Liver:

Omalirel 150mg Injection should be used with caution in patients suffering from liver diseases. Consult with your doctor for advice 

Kidney:

Omalirel 150mg Injection should be used with caution in patients suffering from kidney diseases. Consult with your doctor for advice 

Others:

• Inform your doctor if you have any autoimmune disorders before starting treatment with Omalirel 150mg Injection.

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects; not everyone gets them.

Severe:

• Severe allergic reactions

Common:

• Reaction at the injection site such as swelling, itching and redness
• Fever
• Pain in the abdomen
• Headache (very common in children), dizziness
• Upper respiratory tract infection, inflammation of the pharynx and common cold
• Feeling of pressure or pain in the cheeks and forehead (sinusitis, sinus headache)
• Pain in joints (arthralgia)