-
Avoid grapefruit products and St. John's wort during Palbenz 75mg treatment.
-
Use effective birth control during treatment and:
-
For at least 3 weeks after the final dose (females).
-
For at least 14 weeks after the final dose (males).
-
-
This medication may reduce fertility; consult your doctor if you have concerns.
-
Your doctor may advise regular blood tests to monitor the drug’s effect on your blood cells.
Sourced from:Manufacturer Authorized Distributor
Quick Summary
Palbenz 75mg Capsule
Written By:Guruvigneshwari M.M. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS
Last updated on 04 Apr 2026 | 06:04 AM (IST)
₹5250
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21 CAPSULE(s) IN A BOTTLE
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Introduction
Palbenz 75 mg capsule is a targeted anticancer medication that contains the active ingredient palbociclib. It belongs to the class of cyclin-dependent kinase (CDK) inhibitors and is used in the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. This drug is typically given in combination with other anticancer therapies. If you are looking for Palbenz capsule dosage, your doctor will determine the right dose based on your condition, but Palbenz 75mg dose is usually taken once daily for 21 days followed by a 7-day break. When considering Palbenz vs Palbace 75 mg capsule comparison, it’s important to know that both medications contain palbociclib and are used for the same indication.
Common side effects of Palbenz 75mg capsule may include nausea, vomiting, diarrhea, fatigue, hair loss, dry skin, infections, low blood cell counts, and vision changes. Contact your doctor if these symptoms persist. Before starting this medication, inform your doctor about any allergies, ongoing infections, liver/kidney conditions, or sugar intolerance. If you experience chest pain, dry cough, or breathing difficulty, it may be a sign of lung inflammation—seek immediate medical advice.
Use effective contraception during the course and for at least three weeks after the final dose. The medication is not suitable for individuals under 18 years of age. Avoid taking other medications, supplements, or herbal remedies like St. John's wort without consulting your doctor. For information on the Palbenz 75mg capsule price, contact a licensed pharmacy.
Uses
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Palbenz 75mg Capsule works
Palbenz 75 mg works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Palbenz 75mg Capsule with other drugs
Inform your doctor about all medications including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of Palbenz 75mg with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.
Storage conditions
- Keep Palbenz 75 mg out of sight and reach of children.
- Store at 20°C to 25°C.
How to take Palbenz 75mg Capsule
Take Palbenz 75 mg exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice for Palbenz 75mg Capsule
Breast Feeding
Unsafe
Taking Palbenz 75 mg while breastfeeding is not recommended as it is not known whether it passes into the breast milk.
Alcohol
Consult Your Doctor
It is unknown whether it is safe to drink alcohol while taking Palbenz 75 mg. Check with your doctor for advice.
Liver
Unsafe
Inform your physician if you have any liver disorders before taking Palbenz 75 mg, as it should be used with caution in liver disorder patients.
Lungs
Consult Your Doctor
It is not unknown whether Palbenz 75 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Unsafe
Palbenz 75 mg can cause tiredness. Avoid driving if you are unwell.
Pregnancy
Unsafe
It is not recommended to take Palbenz 75 mg during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Palbenz capsule side effects include
Serious:
- Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
- Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common:
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
Expert Tips
FAQs about Palbenz 75mg Capsule
Q1.
Is Palbenz 75 mg targeted therapy?
Yes, Palbenz 75 mg is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Do you lose hair on Palbenz 75 mg?
Yes, Taking Palbenz 75 mg can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q3.
Can children use Palbenz 75 mg?
No, Palbenz 75 mg is not recommended for adolescents and children under 18.
Q4.
Does Palbenz 75 mg affect fertility?
Yes, Palbenz 75 mg may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q5.
Does Palbenz 75 mg affect blood cell count?
Palbenz 75 mg might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Palbenz 75 mg are advised.
Fact Box
|
Molecule name |
Palbociclib |
|
Therapeutic class |
Cyclin-dependent kinase inhibitor |
|
Pharmacological class |
Anti-Neoplastic drug |
|
Indications |
HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 04 Apr 2026 | 06:04 AM (IST)
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