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Palbobuzz 100 Capsule
Last updated on 19 May 2026 | 06:34 AM (IST)
₹2034
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Introduction
Palbobuzz 100 Capsule is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. It is used in treating hormone receptor-positive, human epidermal growth factor 2–negative advanced or metastatic breast cancer. Cancer is a condition in which cells multiply in an uncontrolled and abnormal manner. This medicine is given in combination with other anticancer medications. Understanding how Palbociclib 100 Capsule Capsule work is important; palbociclib works by inhibiting cyclin-dependent kinases 4 and 6 (CDK4/6), proteins that promote cancer cell division, thereby slowing or stopping tumor growth. This action is linked directly to the Palbobuzz 100 Capsule ingredients, with palbociclib being the primary active component.
The common side effects associated with Palbobuzz 100 mg Capsule include nausea, vomiting, diarrhea, tiredness, hair loss, dry skin, rash, infections, nosebleeds, decreased appetite, low blood cell counts, swelling of the lips and mouth, taste changes, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects disturb or persist. Notify your healthcare provider if you are allergic to Palbobuzz 100 Capsule or any of its ingredients. Before taking this medication, inform your doctor if you have signs of infection (fever, chills, sore throat), liver disorders, kidney disorders, or intolerance to certain sugars.
Consult your physician immediately if you experience symptoms such as dry cough, chest pain, or difficulty breathing, as these could indicate lung inflammation. Always inform your physician about all medicines, including supplements and herbal products, before starting treatment. Effective birth control must be used during treatment and for at least three weeks after the last dose. This medication is not recommended for adolescents or children under 18 years of age.
For patients looking for convenient access, you can Buy Palbobuzz Capsule online through reputable medical platforms. If you wish to proceed, you can also place a Palbobuzz 100 Capsule order through trusted pharmacies that provide verified oncology medications.
Uses
Palbobuzz 100 Capsule uses are
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Palbobuzz 100 Capsule Works
Palbobuzz 100 Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Palbobuzz 100 Capsule with other drugs
Apomorphine (Life-threatening)
Combining palonosetron with apomorphine can cause severe drops in blood pressure and fainting. This combination should be strictly avoided.Other 5-HT3 Antagonists (Severe)
Using palonosetron with drugs like ondansetron or granisetron may increase the risk of heart rhythm disturbances, particularly QT prolongation. Medical supervision is essential.QT-Prolonging Medicines (Severe)
Antiarrhythmics (e.g., amiodarone, sotalol) or certain antipsychotics may add to palonosetron’s potential for QT interval prolongation. ECG monitoring is recommended if combined.CYP3A4 Inducers (Moderate)
Drugs such as rifampicin or carbamazepine can reduce palonosetron levels, potentially lowering its effectiveness. Dose adjustments or alternative therapy may be needed.CYP2D6 Substrates (Moderate)
Palonosetron may slightly affect the metabolism of other CYP2D6 metabolized drugs, like some antidepressants or beta-blockers. Monitoring is recommended.Opioids (Mild)
Concurrent use may slightly increase drowsiness or dizziness. Patients should be cautioned about alertness and driving.
Storage Conditions
Keep Palbobuzz 100 Capsule out of sight and reach of children.
Store at 20°C to 25°C.
How to take Palbobuzz 100 Capsule
Take the Palbobuzz 100 Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this tablet as a whole with a glass of water. Avoid crushing, breaking, or chewing the tablet.
Safety Advices
Pregnancy
It is not recommended to take Palbobuzz 100 Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Breast Feeding
It is not recommended to take Palbobuzz 100 Capsule while breastfeeding as it is not known whether it passes into the breast milk. consult your healthcare provider before taking this tablet.
Lungs
You need to tell your physician if you have any lung disorders before taking Palbobuzz 100 Capsule, as this medication should be used with caution in kidney disorders.
Liver
Inform your physician if you have any liver disorders before taking Palbobuzz 100 Capsule, as it should be used with caution in liver disorders.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Palbobuzz 100 Capsule. Check with your doctor for advice.
Driving
Palbobuzz 100 Capsule can cause tiredness. Avoid driving if you are unwell. Have a word with your healthcare provider before starting the therapy.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Palbobuzz 100 Capsule side effects are
Serious:
Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common:
Tiredness
Hair loss
Dry skin, rash
Infections
Low blood cell counts.
Decreased of appetite
Nausea, vomiting
Expert Tips
Avoid consuming grapefruit, grapefruit juice, and products containing St. John’s wort during treatment.
Use effective birth control during treatment and for at least 3 weeks after the final dose (females) and 14 weeks after the final dose (males).
This medicine may affect fertility. Discuss with your doctor if you have any fertility-related concerns before starting treatment.
Your doctor may advise regular blood tests to monitor how the medicine is affecting your blood cells.
Frequently Asked Questions(FAQs)
Q1.
Do you lose hair on Palbobuzz 100 Capsule?
Yes, Taking Palbobuzz 100 Capsule can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q2.
Can children use Palbobuzz 100 Capsule?
No, Palbobuzz 100 Capsule is not recommended for adolescents and children under 18.
Q3.
Does Palbobuzz 100 Capsule affect fertility?
Yes, Palbobuzz 100 Capsule may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q4.
Does Palbobuzz 100 Capsule affect blood cell count?
Palbobuzz 100 Capsule might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Palbobuzz 100 Capsule are advised.
Fact Box
Molecule Name: | Palbociclib |
Therapeutic class: | Cyclin-dependent kinase inhibitor |
Pharmacological class: | Anticancer agents |
Indications: | HR-positive, HER2-negative advanced or metastatic breast cancer |
References
Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 19 May 2026 | 06:34 AM (IST)
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