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Palbokaas 125mg Capsule
Last updated on 19 Aug 2026 | 06:50 AM (IST)
₹2400
MRP: ₹5999
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21 CAPSULE(s) IN A BOTTLE
Palbokaas 125mg Capsule
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PALBOCICLIBMarketer
ANAKAAS LIFE BIO SCIENCE PVT LTD
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Introduction
Palbokaas 125mg Capsule is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. It is used in treating hormone receptor-positive, human epidermal growth factor 2–negative advanced or metastatic breast cancer, and this aligns with Palbokaas 125mg Capsule uses in clinical practice. Cancer is a condition in which cells multiply in an uncontrolled and abnormal manner. This medicine is given in combination with certain other anticancer medications.
The common Palbokaas 125mg side effects include nausea, vomiting, diarrhea, tiredness, hair loss, dry skin, rash, infections, nosebleeds, decreased appetite, low blood cell counts, swelling of the lips and mouth, taste changes, dry eyes, blurred vision, and increased tearing. Inform your doctor if any of these side effects disturb or persist. Inform your healthcare provider if you are allergic to Palbokaas 125mg Capsule or any of its ingredients. Before taking this medicine, it is vital to inform your doctor if you have any signs of infection (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to certain sugars.
Consult your physician immediately if you experience symptoms such as dry cough, chest pain, or difficulty breathing, as these could indicate lung inflammation. Make sure you inform your physician of all the medicines, including supplements and herbal products, you are taking before starting this medication. Use effective birth control during the treatment and for at least three weeks after the last dose. This medicine is not recommended for adolescents and children under 18 years of age. If required, your doctor may consider a suitable Palbokaas 125mg substitute based on your medical condition and treatment tolerance.
Uses
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Palbokaas 125mg Capsule Works
Palbokaas 125mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Palbokaas 125mg Capsule with other drugs
Inform your doctor about any medications you are taking or have taken before the treatment. Concurrent use of Palbokaas 125mg Capsule with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity.
Storage
Keep Palbokaas 125mg Capsule out of sight and reach of children.
Store at 20°C to 25°C.
How to take Palbokaas 125mg Capsule
Take the Palbokaas 125mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this tablet as a whole with a glass of water. Avoid crushing, breaking, or chewing the tablet.
Safety Advice
Pregnancy
It is not recommended to take Palbokaas 125mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Breast Feeding
It is not recommended to take Palbokaas 125mg Capsule while breastfeeding as it is not known whether it passes into the breast milk. consult your healthcare provider before taking this tablet.
Lungs
You need to tell your physician if you have any lung disorders before taking Palbokaas 125mg Capsule, as this medication should be used with caution in kidney disorders.
Liver
Inform your physician if you have any liver disorders before taking Palbokaas 125mg Capsule, as it should be used with caution in liver disorders.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Palbokaas 125mg Capsule. Check with your doctor for advice.
Driving
Palbokaas 125mg Capsule can cause tiredness. Avoid driving if you are unwell. Have a word with your healthcare provider before starting the therapy.
Side effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common:
Tiredness
Hair loss
Dry skin, rash
Infections
Low blood cell counts.
Decreased of appetite
Nausea, vomiting
Expert Tips
Avoid consuming grapefruit, grapefruit juice, and products containing St. John’s wort during treatment.
Use effective birth control during treatment and for at least 3 weeks after the final dose (females) and 14 weeks after the final dose (males).
This medicine may affect fertility. Discuss with your doctor if you have any fertility-related concerns before starting treatment.
Your doctor may advise regular blood tests to monitor how the medicine is affecting your blood cells.
FAQs
Q1.
Do you lose hair on Palbokaas 125mg Capsule?
Yes, Taking Palbokaas 125mg Capsule can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q2.
Can children use Palbokaas 125mg Capsule?
No, Palbokaas 125mg Capsule is not recommended for adolescents and children under 18.
Q3.
Does Palbokaas 125mg Capsule affect fertility?
Yes, Palbokaas 125mg Capsule may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q4.
Does Palbokaas 125mg Capsule affect blood cell count?
Palbokaas 125mg Capsule might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Palbokaas 125mg Capsule are advised.
Fact box
Molecule Name: | Palbociclib |
Therapeutic class: | Cyclin-dependent kinase inhibitor |
Pharmacological class: | Anticancer agents |
Indications: | HR-positive, HER2-negative advanced or metastatic breast cancer |
References
Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
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Author Details

Written By
Dr Arathy J S
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 19 Aug 2026 | 06:50 AM (IST)

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