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  3. Palbokaas 125mg Capsule

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Quick summary
Quick Summary

Palbokaas 125mg Capsule

Prescription Required
palbociclib
Written By:Dr Arathy J SBDS Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 19 Aug 2026 | 06:50 AM (IST)

₹2400

MRP: ₹5999

(You Save ₹3599)

21 CAPSULE(s) IN A BOTTLE

60% OFF
Palbokaas 125mg Capsule
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4.8 ⭐️ On Google

Palbokaas 125mg Capsule


Prescription Required
Required

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PALBOCICLIB

Marketer

ANAKAAS LIFE BIO SCIENCE PVT LTD

60% OFF

Palbokaas 125mg Capsule
Preview
We are Rated 4.8 ⭐️ On Google

₹2400

MRP: ₹5,999.00

Inclusive of all taxes

60% Off

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21 Capsule(s) In A Bottle

21 Capsule(s) In A Bottle

₹ 114.3/Unit

21 CAPSULE(s) IN A BOTTLE


Prescription Required
Prescription Required

Salt Composition

PALBOCICLIB

Marketer

ANAKAAS LIFE BIO SCIENCE PVT LTD


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Order before timer ends to ensure your medicine is dispatched at...

Substitutes

Palbonamo 125mg Capsule

SHIVNAAM TRADEL...

₹ 107.14/capsule

6% cheaper

Myciclib 125mg Capsule

KHANDELWAL LABO...

₹ 117.86/capsule

4% costlier

Piclib 125mg Capsule

HETERO HEALTHCA...

₹ 122.62/capsule

8% costlier

Palbolieva 125mg Capsule

Allieva Pharma ...

₹ 122.81/capsule

8% costlier

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Introduction

Palbokaas 125mg Capsule is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. It is used in treating hormone receptor-positive, human epidermal growth factor 2–negative advanced or metastatic breast cancer, and this aligns with Palbokaas 125mg Capsule uses in clinical practice. Cancer is a condition in which cells multiply in an uncontrolled and abnormal manner. This medicine is given in combination with certain other anticancer medications.

The common Palbokaas 125mg side effects include nausea, vomiting, diarrhea, tiredness, hair loss, dry skin, rash, infections, nosebleeds, decreased appetite, low blood cell counts, swelling of the lips and mouth, taste changes, dry eyes, blurred vision, and increased tearing. Inform your doctor if any of these side effects disturb or persist. Inform your healthcare provider if you are allergic to Palbokaas 125mg Capsule or any of its ingredients. Before taking this medicine, it is vital to inform your doctor if you have any signs of infection (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to certain sugars.

Consult your physician immediately if you experience symptoms such as dry cough, chest pain, or difficulty breathing, as these could indicate lung inflammation. Make sure you inform your physician of all the medicines, including supplements and herbal products, you are taking before starting this medication. Use effective birth control during the treatment and for at least three weeks after the last dose. This medicine is not recommended for adolescents and children under 18 years of age. If required, your doctor may consider a suitable Palbokaas 125mg substitute based on your medical condition and treatment tolerance.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How Palbokaas 125mg Capsule Works

Palbokaas 125mg Capsule  works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

Interaction of Palbokaas 125mg Capsule with other drugs

Inform your doctor about any medications you are taking or have taken before the treatment. Concurrent use of Palbokaas 125mg Capsule  with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity.

Storage

  • Keep Palbokaas 125mg Capsule out of sight and reach of children.

  • Store at 20°C to 25°C.

How to take Palbokaas 125mg Capsule

Take the Palbokaas 125mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this  tablet as a whole with a glass of water. Avoid crushing, breaking, or chewing the tablet.

Safety Advice

Pregnancy-Unsafe

Pregnancy

Unsafe

It is not recommended to take Palbokaas 125mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.  

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

It is not recommended to take Palbokaas 125mg Capsule while breastfeeding as it is not known whether it passes into the breast milk.  consult your healthcare provider before taking this tablet. 

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

You need to tell your physician if you have any lung disorders before taking Palbokaas 125mg Capsule, as this medication should be used with caution in kidney disorders. 

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Inform your physician if you have any liver disorders before taking Palbokaas 125mg Capsule, as it should be used with caution in liver disorders. 

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown whether it is safe to drink alcohol while taking Palbokaas 125mg Capsule. Check with your doctor for advice.  

Driving-Consult Your Doctor

Driving

Consult Your Doctor

Palbokaas 125mg Capsule can cause tiredness. Avoid driving if you are unwell. Have a word with your healthcare provider before starting the therapy.

Side effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

  • Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)

  • Lung inflammation (chest pain, dry cough, or difficulty breathing)


Common:

  • Tiredness

  • Hair loss

  • Dry skin, rash

  • Infections

  • Low blood cell counts.

  • Decreased of appetite

  • Nausea, vomiting

Expert Tips

  • Avoid consuming grapefruit, grapefruit juice, and products containing St. John’s wort during treatment.

  • Use effective birth control during treatment and for at least 3 weeks after the final dose (females) and 14 weeks after the final dose (males).

  • This medicine may affect fertility. Discuss with your doctor if you have any fertility-related concerns before starting treatment.

  • Your doctor may advise regular blood tests to monitor how the medicine is affecting your blood cells.

FAQs

Q1.

Do you lose hair on Palbokaas 125mg Capsule?

Yes, Taking Palbokaas 125mg Capsule can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.

Q2.

Can children use Palbokaas 125mg Capsule?

No, Palbokaas 125mg Capsule is not recommended for adolescents and children under 18.

Q3.

Does Palbokaas 125mg Capsule affect fertility?

Yes, Palbokaas 125mg Capsule may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.

Q4.

Does Palbokaas 125mg Capsule affect blood cell count?

Palbokaas 125mg Capsule might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Palbokaas 125mg Capsule are advised.

Fact box

Molecule Name: 

Palbociclib 

  Therapeutic class: 

Cyclin-dependent kinase inhibitor

Pharmacological class: 

Anticancer agents

      Indications:

HR-positive, HER2-negative advanced or metastatic breast cancer 

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf

  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf

  3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/

  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Dr Arathy J S

Written By

Dr Arathy J S

BDS


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 19 Aug 2026 | 06:50 AM (IST)

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