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Peglasp 3750IU Injection
Prescription Required
Salt Composition : Peg L-asparaginase
Manufacturer : METTA LIFE SCIENCES PVT LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Peglasp 3750iu Injection
Peglasp 3750IU Injection contains Peg-L-asparaginase. It is used to treat Acute Lymphoblastic Leukemia (cancer of white blood cells) in patients aged four months and above. In Acute Lymphoblastic Leukemia, the white blood cells called lymphocytes multiply uncontrolled and abnormally. This disorder is also known as Acute Lymphocytic Leukemia.
This medicine should not be used if you have severe problems with your pancreas or are allergic to asparaginase or any of the ingredients of this medicine. Talk to your physician if you are a diabetic patient, as this medicine contains glucose. The common side effects of Peglasp 3750IU Injection are muscle pain, nausea, infections, abdominal pain, and diarrhoea.
Use effective birth control during the treatment with Peglasp 3750IU Injection and for at least three months after the last dose. Women should use contraception methods other than oral contraceptives.
Uses of Peglasp 3750iu Injection
- Acute Lymphoblastic Leukemia (ALL)
Therapeutic Effects of Peglasp 3750iu Injection
Cancer cells need a substance called asparagine to survive. Peglasp 3750IU Injection works by lowering the levels of asparagine in the body.
Interaction of Peglasp 3750iu Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Peg-L-asparaginase and can cause undesirable side effects.
More Information about Peglasp 3750iu Injection
- Keep Peglasp 3750IU Injection out of sight and reach of children.
- Store in a refrigerator (2°C to 8°C).
How to consume Peglasp 3750iu Injection
It will be given to you by your healthcare professional. Your doctor will decide the dose and dosage of your treatment based on the disease condition and other factors. Do not self-administer.
Safety Advices for Peglasp 3750iu Injection
Pregnancy
You should not take Peglasp 3750IU Injection if you are pregnant or planning to get pregnant because it may cause birth defects.
Breast Feeding
You must not breastfeed your baby during treatment with Peglasp 3750IU Injection. You need to tell your physician if you are breastfeeding before taking this medicine.
Lungs
Limited information is available on the safety of Peglasp 3750IU Injection in patients with lung problems. Inform your physician if you have lung disease or disorders before initiating the treatment.
Liver
You need to tell your physician if you have any liver disorders before taking Peglasp 3750IU Injection.
Alcohol
It is unknown whether it is safe to consume alcohol while taking Peglasp 3750IU Injection. Inform your physician if you are a chronic drinker.
Driving
Peglasp 3750IU Injection can cause dizziness and drowsiness. Avoid driving if you are unwell.
Side Effects of Peglasp 3750iu Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Severe allergic reactions
- High blood sugar levels
- Bleeding
- Liver and nervous problems
- Pain near your stomach (inflammation of the pancreas)
- Blood clots in arm or leg
- Pain, bruising, swelling, or hardening of the skin at the injection site
Common:
- Nausea
- Muscle pain
- Weight loss
- Infections (fever, rapid heart rate, confusion, or a rash)
- Difficulty breathing
- Inflammation of the digestive tract
- Diarrhea
- Abdominal pain, discomfort
- Headache
- Tiredness
Word of Advice
This injection should be administered only by the doctor or nurse. Inform the doctor if the patient has any allergic response, blood pressure, kidney, or liver problems and medication taken for different medical conditions. Consult the doctor if the patient is pregnant or breastfeeding mother before taking this medication. Avoid driving while taking this medication, as it can cause dizziness. Avoid handling heavy pieces of machinery as the patient may lack concentration.
FAQs
Q 1. Can Peglasp 3750IU Injection affect blood glucose levels?
Yes, this medication can increase blood glucose levels as it contains glucose. Blood glucose levels should be monitored regularly while taking this medication.
Q 2. Can Peglasp 3750IU Injection be self administered?
No, this injection should be administered only by the doctor or nurse and should not be self-administered. Wrong injection techniques can lead to complications.
Q 3. Can I use Peglasp 3750IU Injection while driving?
Avoid driving and handling heavy machinery while taking this medication, as it causes dizziness and lack of concentration.
Q 4. Is it safe to use Peglasp 3750IU Injection during breastfeeding?
It is unsafe to use this medication during breastfeeding and inform the doctor before taking this medication.
Q 5. Is Peg-L-asparaginase a chemotherapy medication?
Yes, it is a chemotherapy medicine which is used to treat Acute Lymphoblastic Leukemia (cancer of white blood cells).
Fact Box of Peglasp 3750iu Injection
Molecule name: Peg-L-Asparaginase | Therapeutic class: Anti-neoplastics |
Pharmacological Class: Enzyme
| Indications: Acute Lymphoblastic Leukemia (ALL) |
References
1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1720.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 869.
3. Porton Biopharma Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 9th August 2021], https://www.medicines.org.uk/emc/files/pil.12340.pdf
4. Merck & Co., Inc., US Food and Drug Administration, [Issued on 2000] [ Accessed on 5th August 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/aspamer080102LB.pdf
Disclaimer
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