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Pentasa 500mg Tablet
Last updated on 29 Aug 2026 | 11:06 AM (IST)
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Introduction to Pentasa 500mg Tablet
Pentasa 500mg tablet is an anti-inflammatory drug that contains the active ingredient Mesalazine. It belongs to the family known as aminosalicylates. It is used to treat ulcerative colitis and Crohn’s ileocolitis. Ulcerative colitis and Crohn's ileocolitis are inflammatory bowel diseases (IBD). Ulcerative colitis mainly inflames the colon and rectum, causing diarrhea and rectal bleeding. Crohn's ileocolitis affects the small intestine and colon, involving deeper layers of the intestinal wall and leading to abdominal pain, weight loss, and complications.
Do not take Pentasa 500mg tablet if you are allergic to Mesalazine, aspirin, salicylate, or any of its ingredients. Do not take this medicine if you have severe kidney disease or blood abnormalities while taking other medicines, such as sulphasalazine. This medicine is not for use in children under the age of 2. Inform your doctor if you have or have had a history of severe skin rash or skin peeling, blistering, and mouth sore.
Before initiating Pentasa 500mg tablet treatment, your kidney and blood function will be assessed through tests. Your doctor will periodically monitor your liver, kidney, and blood health using blood and urine samples throughout your treatment. Pentasa 500mg tablet use may lead to kidney stones, which could cause abdominal pain and blood in urine. Ensure proper hydration during Pentasa 500mg tablet treatment.
Uses of Pentasa 500mg Tablet
- Ulcerative colitis
- Crohn’s ileocolitis
Therapeutic Effects of Pentasa 500mg Tablet
Pentasa 500mg tablet works by reducing gut inflammation. It inhibits inflammatory compounds, counters free radicals, and adjusts the immune response, providing relief, promoting healing, and managing these conditions.
Interaction of Pentasa 500mg Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications, such as Lactulose, interact with Pentasa 500mg tablet and reduce their effectiveness by causing undesirable side effects.
More Information about Pentasa 500mg Tablet
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications, such as Lactulose, interact with Pentasa 500mg tablet and reduce their effectiveness by causing undesirable side effects.
How to consume Pentasa 500mg Tablet
Take Penatasa 500mg tablet exactly as directed by your doctor. Your doctor will provide the appropriate dose and frequency based on your medical condition and other factors. Do not crush or chew the tablets. Swallow the tablets whole with water. If you take an excess tablet more than the prescribed dosage, drink plenty of water and contact your doctor immediately and don't double the dosage of the medicine if you forgot to take the medicine.
Safety Advice for Pentasa 500mg Tablet
Breast Feeding
Do not use Pentasa 500mg tablet unless your doctor advises. It is unknown whether Pentasa 500mg tablet is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
Alcohol
It is unknown whether consuming alcohol while taking Pentasa 500mg tablet is safe or not. So, consult your doctor for more information.
Liver
Pentasa 500mg tablet should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions.
Lungs
It is unknown whether Pentasa 500mg tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Pentasa 500mg tablet doesnt alter the capacity of driving or operating machinery. Contact your doctor for more information.
Pregnancy
Do not use Pentasa 500mg tablet unless your doctor advises. Notify your healthcare professional if you are pregnant or planning to have a baby; think you may be pregnant so that your doctor may decide to give you this medicine if the expected benefits outweigh any potential risks.
Side Effects of Pentasa 500mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Unexpected nose bleeds, bleeding gums, bruising more easily
- Problems with kidney function
- Skin rash with flaking, boils or sore lips, or mouth
- Fever, sore throat
- Mouth or lip ulcers
- Spots underneath your skin
- Swollen ankles
Common
- Diarrhea
- Abdominal pain
- Nausea
- Headache
- Indigestion
- Bloating
- Muscle pain
Word of Advice
Follow the prescribed dosage and usage instructions provided by your healthcare professional. Inform your doctor about any known allergies or medical conditions you have before receiving Pentasa 500mg tablet. Do not consume this medicine if you have kidney related condition. Before stating the treatment inform your doctor if you have liver condition as this medicine is cautiously recommended in such conditions. If you notice any unexpected or severe side effects, like an allergic reaction, seek immediate medical attention. Inform your healthcare professional about any other medications or supplements you are consuming to avoid potential drug interactions. If you have any concerns regarding the treatment, consult your healthcare professional for information.
FAQs about Pentasa 500mg Tablet
Q1.
How can I manage side effects while taking Pentasa 500mg tablet?
If you observe any side effects while taking Pentasa 500mg tablet, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your symptoms. You should contact your physician if your side effects are severe or persistent.
Q2.
Can I give the Pentasa 500mg tablet to children?
No, Pentasa 500mg tablet should not be given to children under 2 years of age. It's important to follow the recommended age guidelines and consult a healthcare professional for appropriate pediatric dosing and alternatives for younger children.
Q3.
Are there any dietary restrictions while taking Pentasa 500mg tablet?
There are no specific dietary restrictions associated with these medications. However, it is recommended to maintain a healthy and balanced diet to support overall health and well-being.
Q4.
Can Pentasa 500mg tablet be taken during pregnancy or while breastfeeding?
It is unsafe to consume Pentasa 500mg tablet during pregnancy and breastfeeding. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your doctor will decide whether you should use this medicine.
Q5.
How long does it take for Pentasa 500mg tablet to start working?
The time it takes for the Pentasa 500mg tablet to start working varies from person to person. However, it is important to continue taking the medication as your healthcare provider prescribes to achieve optimal treatment outcomes.
Q6.
What are the side effects of Pentasa 500mg tablet?
The common side effects of Pentasa 500mg tablet are diarrhea, abdominal pain, nausea, headache, indigestion, bloating, and muscle pain.
Fact Box of Pentasa 500mg Tablet
Molecule name: Mesalazine | Therapeutic class: Anti-inflammatory drug |
Pharmacological class: Aminosalicylates | Indications: 1. Ulcerative colitis 2. Crohn’s ileocolitis |
References
- AbbVie Lt, Electronic Medicines Compendium (EMC), [Revised on May 2023] [Accessed on 31st August 2023], pil.2217.pdf (medicines.org.uk)
- Actavis Pharma, Inc., US Food and Drug Administration, [Revised on Sept 2015] [Accessed on 31st August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/204412s006lbl.pdf
- KD Tripathi, Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics, Essentials of Medical Pharmacology, 8th Edition, 2019, 209-226.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 29 Aug 2026 | 11:06 AM (IST)
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