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Pirfenex 801mg Tablet
Last updated on 31 Aug 2026 | 06:42 AM (IST)
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Introduction
Pirfenex 801mg tablet belongs to the medication class known as transforming growth factor inhibitors. It contains an active ingredient called Pirfenidone. It is used to treat idiopathic pulmonary fibrosis (IPF). Idiopathic pulmonary fibrosis is a type of lung disorder in which tissues of the lungs become scarred and inflamed, resulting in breathing difficulties. This medicine should not be used if you have severe liver disorders or kidney disorders, if you are taking fluvoxamine (which treats depression and obsessive-compulsive disorder), or if you are allergic to any of the ingredients of this medicine. Do not drink grapefruit juice while taking this medicine.
This medicine may cause gastrointestinal disorders and elevation in liver enzymes. If you experience any of these, temporary dodge or discontinuation may be required. Consult your doctor for more information. Contact your doctor immediately if you experience any abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice. This medicine is not recommended for adolescents and children under 18. Avoid smoking as it may reduce the efficacy of the Pirfenex 801mg tablet. Avoid exposure to sunlight, including sunlamps. Use sunscreen daily and cover your head, legs, and arms to reduce exposure to sunlight. Pirfenex 801mg tablet price varies by location and retailer.
Uses
Pirfenex 801mg uses are:
- Idiopathic pulmonary fibrosis
How Pirfenex 801mg Tablet Works
Pirfenex 801mg tablet works to reduce the production and accumulation of extracellular matrix (ECM) proteins, which contribute to the fibrosis and stiffening of lung tissue. This helps to slow the progression of the disease and improve lung function.
Interaction of Pirfenex 801mg Tablet with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications, such as Ciprofloxacin and Fluvoxamine, may interact with the effects of Pirfenex 801mg tablet and reduce its effectiveness by causing undesirable side effects. your healthcare professional fix pirfenex 801mg dosage.
Storage Conditions
- Keep the Pirfenex 801mg tablet out of sight and reach of children.
- Store at a temperature of 25°C
- Store in the original package
- Do not refrigerate
How to take Pirfenex 801mg Tablet
Take Pirfenex 801mg tablet in a dose and duration prescribed by your doctor. Swallow the tablets whole with water. Take the tablet after a meal at the same time each day to reduce the side effects. Do not crush or chew the tablets. Do not drink grapefruit juice while taking this medication.
Safety Advice for Pirfenex 801mg Tablet
Breast Feeding
It is not recommended while taking Pirfenex 801mg tablet. Because the medicine can pass into breast milk, potentially harming a nursing infant. Consult the doctor for more information.
Alcohol
It is unknown if drinking alcohol while taking a Pirfenex 801mg tablet is safe. Please speak with your physician.
Liver
Pirfenex 801mg tablet is contraindicated in patients with severe liver disorders. Before starting the treatment, performing a liver function test is recommended. Notify your doctor if you have any liver disorders before taking this medicine. Contact your doctor immediately if you experience any abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice.
Lungs
Consult your doctor if you experience any upper respiratory tract infection while taking Pirfenex 801mg tablet.
Driving
Pirfenex 801mg tablet may cause dizziness or sleepiness. So it is unsafe to drive while you are under this treatment.
Pregnancy
Pirfenex 801mg tablet may cause harm to the unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medicine.
Side Effects
Pirfenex 801mg side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of face, lips, or tongue, wheezing, feeling faint)
- Liver problems (yellowing of skin or eyes, dark urine, bruising, or bleeding)
Common
- Nausea, vomiting
- Loss of appetite, tiredness
- Diarrhea, indigestion
- Headache, dizziness
- Skin reactions after exposure to sunlight
- Infections
- Weight loss
- Difficulty sleeping
- Changes in taste
- Cough
- Stomach pain, constipation, feeling bloated, heartburn
- Itchy, dry skin
- Muscle pain, joint pain
- Chest pain, shortness of breath
Expert tips
-
Consult your doctor immediately if you experience any side effects such as dark or brown urine, unusual bruising or bleeding, or jaundice.
-
Avoid smoking during treatment, as it may reduce the effectiveness of Pirfenex 801mg Tablet.
-
Limit exposure to sunlight and avoid sunlamps. Use sunscreen and cover your head, arms, and legs to protect your skin.
-
Liver function tests are recommended before starting treatment to ensure safe use.
FAQs about Pirfenex 801mg Tablet
Q1.
How does Pirfenex 801mg tablet work?
Pirfenex 801mg tablet works by reducing inflammation and fibrosis in the lungs. It inhibits the production of certain molecules that cause scarring and stiffening of the lung tissue.
Q2.
How long should I take Pirfenex 801mg tablet?
Pirfenex 801mg tablet is a long-term medication that is taken indefinitely for treating IPF. Anyways, the duration of treatment may vary depending on the individual patient's response to the medication and other factors.
Q3.
Who should not take Pirfenex 801mg tablet ?
Pirfenex 801mg tablet is not recommended for pregnant or breastfeeding women and those with severe liver or kidney disease.
Q4.
What dosage of Pirfenex 801mg tablet should I take?
It is important to note that the dosage of Pirfenex 801mg tablet may vary based on factors such as the patient's age, weight, renal function, and other medications they may be taking. Dosage adjustments may be necessary based on side effects or changes in the patient's condition. As with all medications, it is important to follow the dosage instructions provided by your healthcare provider and to consult with them if you have any questions or concerns.
Q5.
What should I do if I miss a dose of Pirfenex 801mg tablet?
If you miss a dose of Pirfenex 801mg tablet, take it as soon as you remember. Skip the missed dose and continue with your regular dosing schedule.
Q6.
What tests should I take before starting Pirfenex 801mg tablet?
Your doctor will recommend you to take a liver function test before starting the cycles with Pirfenex 801mg tablet to monitor the functioning level.
Fact Box
|
Molecule name: Pirfenidone |
Therapeutic class: Antifibrotic drugs |
|
Pharmacological class: Transforming growth factor inhibitor |
Indication: Idiopathic pulmonary fibrosis |
References
- Roche Products Limited, Electronic medicines compendium (emc), [Revised on Nov 2020] [Accessed on 1st April 2023] https://www.medicines.org.uk/emc/files/pil.2731.pdf
- Genentech USA, Inc, US Food and Drug Administration, [Revised on Jan 2017], [Accessed on 1st April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208780s000lbl.pdf
- Pirfenex Tablets; Cipla Ltd; Ciplamed; Accessed on 1st April 2023; https://www.ciplamed.com/content/pirfenex-tablets
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Aug 2026 | 06:42 AM (IST)
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