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Pivikto 150mg Tablet
Last updated on 22 Sep 2026 | 11:05 AM (IST)
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Introduction
Pivikto 150mg Tablet contains the active ingredient Alpelisib and belongs to the class of PI3K (phosphatidylinositol-3-kinase) inhibitors. It is primarily used in combination with other anticancer medications to treat metastatic breast cancer in women who have undergone menopause or in men whose cancer progressed during or after other treatments. Pivikto is also indicated for certain types of PIK3CA-related overgrowth spectrum (PROS), a genetic condition that causes overgrowth and tissue abnormalities.
Patients should follow Pivikto dosage instructions carefully and only take the medicine as prescribed by their healthcare provider. It is important to store the medication according to Pivikto storage instructions to maintain its efficacy. Use of Pivikto requires caution in individuals with kidney or liver issues, and patients should discuss these conditions with their doctor prior to starting therapy. Monitoring for potential side effects, including hyperglycemia, is recommended.
For women who are pregnant or planning pregnancy, consult a physician regarding Pivikto pregnancy safety. While taking this medication, long-term use safety should be evaluated with regular follow-ups. Patients can purchase the medicine online with options like Buy Pivikto 150 online, and should be aware of available Pivikto alternatives. Pivikto is manufactured by Novartis India, and its Pivikto price India may vary depending on location and pharmacy.
Uses
Pivikto 150 uses are
HER2- negative Breast cancer
How Pivikto 150mg Tablet works
Pivikto 150mg tablet is a kinase inhibitor of phosphatidylinositol-3-kinase (PI3K) with inhibitory activity predominantly against PI3K-alpha. In breast cancer cell cells, PI3K inhibition by this medicine induces an increase in estrogen receptor transcription. These enzymes help cancer cells to grow and multiply. By blocking their action, it can reduce cancer growth and spread and help destroy cancer cells.
Interaction of Pivikto 150mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Pivikto 150mg tablet and reduce its effectiveness by causing undesirable side effects.
Storage conditions
- Store the Pivikto 150mg tablet at 20°C to 25°C
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to take Pivikto 150mg Tablet
Your doctor will decide the dose and duration of Pivikto 150mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, immediately after food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. If you cannot swallow the tablet, mix the tablets into a glass of water as per doctor advice.
Safety Advice for Pivikto 150mg Tablet
Breast Feeding
Breastfeeding is not recommended in patients taking Pivikto 150mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is not known whether it is safe to consume alcohol with Pivikto 150mg tablet. Please consult your doctor.
Liver
Pivikto 150mg tablet is safe to use in patients with liver problems. There is no need for dose adjustments. Inform your physician if you have any liver disease before initiating the therapy.
Lungs
It is unknown whether Pivikto 150mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Pivikto 150mg tablet may alter your ability to drive and operate heavy machinery. The treatment may cause tiredness hence avoid activities after taking the medicine.
Pregnancy
Do not take Pivikto 150mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 1 week after the last dose.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Pivikto 150 side effects are
Common
- Hair loss
- Decreased weight
- Decreased appetite
- Nausea, vomiting
- Tiredness
Serious
- Cellulitis
- Hyperglycemia
- Diarrhea
- Hypersensitivity reactions
- Pneumonitis
- Dehydration
- Angioedema
Expert Tips
-
Your doctor may prescribe medicines to prevent nausea and vomiting before treatment.
-
If you vomit after taking the tablet, take the next dose at the regular scheduled time.
-
Women should use effective birth control during treatment and for 1 week after the last dose.
-
Male patients with female partners should also use effective birth control during treatment and for 1 week after the last dose.
-
Inform your doctor if you have kidney disease, lung disease, breathing problems, or diabetes.
-
Do not breastfeed while on treatment and for 1 week after the last dose.
-
Your doctor may recommend regular blood tests during treatment to monitor for unwanted side effects.
FAQs about Pivikto 150mg Tablet
Q1.
Can a patient with kidney problems take Pivikto 150mg tablet?
Pivikto 150mg tablet should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.
Q2.
What if I overdose or take two doses of Pivikto 150mg tablet?
If you unknowingly overdosed or took two doses of Pivikto 150mg tablet, immediately inform your healthcare professional and seek medical advice.
Q3.
Should Pivikto 150mg tablet be taken with or without food?
Pivikto 150mg tablet comes as a tablet to take by mouth. It is usually taken immediately after the food. Take the tablets as prescribed by your doctor.
Q4.
Does Pivikto 150mg tablet cause hair loss?
Thinning or loss of your hair will usually start within two to four weeks of your first dose of Pivikto 150mg tablet. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.
Q5.
Does Pivikto 150mg tablet cause an increase in sugar levels?
Pivikto 150mg tablet is intended to cause hyperglycemia because it blocks the intracellular action of insulin systemically. This mechanism of action creates a transient state of insulin resistance and hyperglycemia, a common adverse event observed.
Fact Box of Pivikto 150mg Tablet
|
Molecule name |
Alpelisib |
|
Therapeutic class |
Antineoplastics |
|
Pharmacological class |
PI3K Inhibitors |
|
Indications |
Breast Cancer |
References
Piqray 200 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Revised September 2022. Accessed April 28, 2023. https://www.medicines.org.uk/emc/product/11684/smpc
Piqray - alpelisib; Revised on 2019. Accessed April 28, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212526s000lbl.pdf
Kui-Jin Kim, et al., PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer, Scientific Reports, Jul 2020, [Accessed April 28, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378194/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get accurate and trustworthy information that is reviewed by experts. The contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 22 Sep 2026 | 11:05 AM (IST)
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