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Premarin Vaginal 14gm Cream
Last updated on 26 Sep 2026 | 08:43 AM (IST)
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Introduction to Premarin Vaginal 14gm Cream
Premarin Vaginal 14gm Cream is an hormone replacement therapy contains the active ingredient Conjugate Estrogen. It is an a female sex hormone that belongs to the family known as estrogens. It is used to treat menopausal symptoms in and around the vagina (such as itching, dryness, burning, and pain). It is used to treat painful intercourse caused by menopausal changes of the vagina.
Do not take Premarin Vaginal 14gm Cream if you are allergic to Conjugate Estrogen, or any of its ingredients. Do not initiate the use of this medicine if you experience unusual vaginal bleeding, have a history of certain cancers, including breast or uterine cancer, have had a stroke or heart attack, suffer from blood clot issues, have liver problems, a diagnosed bleeding disorder. Consult your healthcare provider if you have or have had cancer before considering the use of this medicine. If you suspect pregnancy, avoid using the cream.
Inform your doctor about any unusual vaginal bleeding, as postmenopausal vaginal bleeding could indicate uterine cancer. Share your complete medical history, especially conditions like asthma, epilepsy, diabetes, migraine, endometriosis, lupus, heart, liver, thyroid, kidney issues, or elevated blood calcium levels. Disclose all medications, including prescriptions, non-prescriptions, vitamins, and herbs, as interactions with Premarin Vaginal 14gm Cream are possible. If you are planning for surgery or bedrest, consult your healthcare provider, and if breastfeeding, be aware that the cream's estrogen hormones may pass into breast milk. Also, notify your physician about any gallbladder disease risk, as estrogens can elevate this risk. Discontinue estrogen use if severe hypercalcemia, vision loss, extreme hypertriglyceridemia, or cholestatic jaundice arises. For women on thyroid replacement therapy, closely monitor thyroid function.
Uses of Premarin Vaginal 14gm Cream
- To treat menopausal changes in and around the vagina.
- To treat painful intercourse.
Therapeutic Effects of Premarin Vaginal 14gm Cream
Conjugated estrogens Cream exerts its mechanism of action in the body by replacing the declining levels of estrogen, a female sex hormone, which helps alleviate the symptoms associated with menopause.
Interaction of Premarin Vaginal 14gm Cream with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications interact with Premarin Vaginal 14gm Cream and reduce their effectiveness by causing undesirable side effects.
More Information about Premarin Vaginal 14gm Cream
- Store Premarin Vaginal 14gm Cream at 15°C - 30°C.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets.
- Always look for the expiration date before consuming it.
How to consume Premarin Vaginal 14gm Cream
For external use only. It is important to apply enough cream evenly on the affected area that needs treatment and gently massage it into the skin until it is fully absorbed. Avoid contact with eyes. Apply Premarin Vaginal 14gm Cream as your doctor recommends.
Safety Advice for Premarin Vaginal 14gm Cream
Breast Feeding
Breastfeeding is not recommended in women taking Premarin Vaginal 14gm Cream because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is unknown whether alcohol may interact with Premarin Vaginal 14gm Cream. Inform your physician if you drink alcoholic beverages.
Liver
Premarin Vaginal 14gm Cream should be cautiously administered in patients with liver diseases. Dose adjustments are necessary. However, inform your physician of any liver diseases before initiating the therapy.
Lungs
It is unknown whether Premarin Vaginal 14gm Cream is safe to be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.
Driving
It is unknown whether Premarin Vaginal 14gm Cream impacts in drive or operate machinery capacity. Contact your doctor for more information.
Pregnancy
Do not use Premarin Vaginal 14gm Cream if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.
Side Effects of Premarin Vaginal 14gm Cream
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Hypersensitivity allergic reaction
Common
- Headache
- Breast pain
- Irregular vaginal bleeding or spotting
- Abdominal cramps, bloating
- Nausea, vomiting
- Hair loss
- Fluid retention
- Vaginal yeast infection
Word of Advice
Follow the prescribed dosage and usage instructions provided by your healthcare professional. Inform your doctor about any known allergies or medical conditions you have before receiving Premarin Vaginal 14gm Cream. If you notice any unexpected or severe side effects, like an allergic reaction, seek immediate medical attention. Inform your healthcare professional about any other medications or supplements you are consuming to avoid potential drug interactions. If you have any concerns regarding the treatment, consult your healthcare professional for information.
FAQs about Premarin Vaginal 14gm Cream
Q1.
How can I manage side effects while taking Premarin Vaginal 14gm Cream?
If you observe any side effects while taking Premarin Vaginal 14gm Cream, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your symptoms. You should contact your physician if your side effects are severe or persistent.
Q2.
Are there any dietary restrictions while taking Premarin Vaginal 14gm Cream?
There are no specific dietary restrictions associated with these medications. However, it is recommended to maintain a healthy and balanced diet to support overall health and well-being.
Q3.
How long does it take for Premarin Vaginal 14gm Cream to start working?
The time it takes for the Premarin Vaginal 14gm Cream to start working varies from person to person. However, it is important to continue taking the medication as your healthcare provider prescribes to achieve optimal treatment outcomes.
Q4.
What are the side effects of Premarin Vaginal 14gm Cream?
The common side effects of Premarin Vaginal 14gm Cream are headache, breast pain, irregular vaginal bleeding or spotting, abdominal cramps, bloating, nausea, vomiting, hair loss, fluid retention, and vaginal yeast infection.
Fact Box of Premarin Vaginal 14gm Cream
Molecule name: Conjugate Estrogen | Therapeutic class: Hormone replacement therapy |
Pharmacological class: Estrogens | Indications:
|
References
- Pfizer Limited, [Revised on Sept 2018] [ Accessed on 31th August 2023], http://labeling.pfizer.com/showlabeling.aspx?id=132§ion=PPI
- Pfizer, US Food and Drug Administration, [Revised on Dec 2015] [ Accessed on 31th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020216s083lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Estrogens, progestins, and contraceptives, 7th edition, 2013, 308 - 310.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Estrogens and progestins, 12th edition, 2011, 1175.
Disclaimer
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Author Details
Written By
Aswini Priya Velmurugan
PG in Biotechnology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:43 AM (IST)
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