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Prilox Cream 5gm
Last updated on 05 Aug 2026 | 07:10 AM (IST)
₹124
MRP: ₹155.5
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Prilox 5 g Cream is a topical medicine used to relieve pain, itching, and discomfort from minor skin irritations, burns, insect bites, or injuries. It contains lidocaine, a local anesthetic that numbs the affected area to reduce pain sensations.
Sourced from:Manufacturer Authorized Distributor
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₹124
MRP: ₹155.50
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Prilox Cream 10gm
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Prilox 30gm Cream
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Introduction
Prilox Cream 5gm contains two active ingredients Lidocaine, Prilocaine in one tablet, which belongs to the group of medications called local anesthetics. This combination is used to treat topically (on the skin) to numb the skin or mucous membranes before certain medical procedures or minor surgeries. They can also reduce pain or discomfort associated with certain skin conditions.
Do not take Prilox Cream 5gm if you are allergic to it, other similar local anesthetics, or any other ingredients in the cream. Avoid getting this cream in your eyes, as it can cause irritation. If this cream accidentally comes into contact with your eye, rinse it thoroughly with lukewarm water or a salt (sodium chloride) solution. Avoid exposing your eye to anything until the sensation returns. Before using this cream, notify your physician if you or your child have a rare inherited illness called 'glucose-6-phosphate dehydrogenase deficiency.' This condition affects blood and may require special consideration when using this cream.
Do not use this cream on areas with skin rash, cuts, scrapes, or other open wounds, except for leg ulcers. If any of these issues are present, consult your physician before using the cream. If you are pregnant, think you might be pregnant, or are planning to have a baby, it's essential to consult your physician before using this cream. Some active substances in Prilox Cream 5gm can be passed into breast milk. However, the amount that transfers is very small and generally considered safe for breastfeeding infants. Prilox Cream price varies by retailer and location. You can buy Prilox Cream online at MrMed.
Uses
Prilox Cream uses to Treatment of local pain relief
How Prilox Cream 5gm Works
Prilox Cream 5gm work by blocking nerve signals in the body. They inhibit the transmission of pain signals from the nerves to the brain, resulting in temporary numbness in the treated area.
Interaction of Prilox Cream 5gm with other drugs
Class III Antiarrhythmics (Moderate)
Medicines like amiodarone may enhance cardiac-related effects of local anesthetics. Use together only with medical advice.Other Local Anesthetics (Moderate)
Using multiple anesthetic products can increase systemic absorption and toxicity. Avoid combining unless prescribed.Drugs That Cause Methemoglobinemia (Severe)
Medicines such as nitrates, sulfonamides, dapsone, or benzocaine can raise the risk of methemoglobinemia when used with Prilox. Seek immediate care if you notice blue lips, dizziness, or breathing difficulty.Beta Blockers (Moderate)
Beta blockers may reduce lidocaine clearance, slightly increasing side effects. Use cautiously under medical supervision.Cimetidine (Moderate)
This medicine can slow lidocaine metabolism, increasing the chance of toxicity if used frequently or over large skin areas. Consult your doctor before combined use.
Storage Conditions
Store the Prilox Cream 5gm at room temperature (20°C to 25°C).
Keep it out of reach of children and pets.
How to Use Prilox Cream 5gm
Prilox Cream 5gm should only be used under the supervision of a doctor or nurse. For surface skin procedures, your physician will apply a generous amount of the cream or gel to cover the area. Gently rub or massage it into the skin, and ensure it remains in contact with the skin for the recommended duration.
Safety Advice for Prilox 5gm Cream
Breast Feeding
Some active substances in Prilox Cream 5gm can be passed into breast milk. However, the amount that transfers is very small and generally considered safe for breastfeeding infants.
Alcohol
It is unknown whether consuming alcohol interacts with Prilox Cream 5gm. Please consult your doctor for more advice.
Liver
It is unknown whether Prilox Cream 5gm is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Lungs
Whether Prilox Cream 5gm can be used in patients with lung disorders is unknown. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Prilox Cream 5gm is unlikely to significantly influence your ability to drive or operate machinery when used at recommended doses.
Pregnancy
If you are pregnant, think you might be pregnant, or are planning to have a baby, it's essential to consult your physician before using Prilox Cream 5gm.
Side Effects
Prilox Cream side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Allergic reactions
Methaemoglobinaemia
Common
Skin reactions
Expert tips
• Avoid activities that could cause accidental injury while the area is numb, as you may not feel pain or discomfort.
• Do not bite your lip or cheek if the cream is applied inside the mouth to prevent accidental injury.
• If you cannot eat or drink right after the procedure due to numbness, remain cautious until sensation returns.
• Stay hydrated by sipping water regularly even if you cannot feel your mouth or throat properly.
• Prevent dehydration, as it can lead to further complications during recovery.
FAQs about Prilox 5gm Cream
Q1.
How long does the numbing effect of Prilox Cream 5gm last?
The duration of numbness varies but typically lasts for about 1 to 2 hours after application of Prilox Cream 5gm. It may vary based on the specific formulation and concentration used.
Q2.
Can I use Prilox Cream 5gm for tattoos or piercings?
Prilox Cream 5gm is sometimes used to reduce pain during tattooing or piercing procedures, but it's essential to consult with a physician and follow their guidance for proper application.
Q3.
How should I apply Prilox Cream 5gm?
You should apply a thin layer of the Prilox Cream 5gm to the area to be numbed, ensuring that it covers the entire surface. It's important to avoid using excessive amounts. Overuse can lead to complications.
Q4.
What are Prilox Cream 5gm used for?
Prilox Cream 5gm is commonly used to numb the skin before procedures such as needle insertion, minor skin surgery, tattoo removal, or laser therapy.
Q5.
How does Prilox Cream 5gm work?
Prilox Cream 5gm works by blocking nerve signals in the body. They inhibit the transmission of pain signals from the nerves to the brain, resulting in temporary numbness in the treated area.
Fact Box
Molecule name: | Lidocaine + Prilocaine |
Therapeutic class: | Topical anaesthetics |
Pharmacological class: | Local anaesthetic agents |
Indications: | Treatment of local pain relief |
References
- AstraZeneca UK Limited, Electronic medicines compendium (EMC), [Revised on Feb 2021] [Accessed on 5th Sep 2023], https://www.medicines.org.uk/emc/files/pil.7994.pdf
- IGI Laboratories Inc., US Food & Drug Administration, [Revised on Nov 2018] [Accessed on 5th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/019941s021lbl.pdf
- Stefan Lillieborg, et al., EMLA anaesthetic cream for debridement of burns: a study of plasma concentrations of Lidocaine + Prilocaine and a review of the literature, Int J Burn Trauma 2017, 7(6), 88-97, [Accessed on 5th Sep 2023], http://www.ijbt.org/files/ijbt0065151.pdf
- L. Peng et al., Local dermal application of a compound lidocaine cream in pain management of cancer wounds, Brazilian Journal of Medical and Biological Research, 2019, 52(11), [Accessed on 5th Sep 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853073/pdf/1414-431X-bjmbr-52-11-e8567.pdf
- KD Tripathi, Local Anaesthetics, Essentials of Medical Pharmacology, 8th Edition, 2019, 386-398.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. B. Deiva
Pharm D

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 05 Aug 2026 | 07:10 AM (IST)

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