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Primcyv 125mg Capsule
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹71250
MRP: ₹89062.5
(You Save ₹17812.5)
21 CAPSULE(s) IN A BOTTLE
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Introduction
Primcyv 125mg Capsule is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medicines called cyclin-dependent kinase inhibitors. This drug is commonly prescribed for the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer, a condition in which cancer cells grow uncontrollably and spread to other parts of the body. It is usually given in combination with other anticancer medications for better effectiveness.
Patients who wish to buy Primcyv 125mg online should ensure they purchase only from trusted and licensed pharmacies with a valid prescription. The exact Primcyv dosage depends on the individual’s medical condition and should always be taken as directed by the oncologist.
When comparing Primcyv vs Ibrance, both contain palbociclib as the active ingredient but may vary in terms of branding, pricing, and availability. In cases where this medicine is not suitable or available, doctors may prescribe Primcyv substitutes depending on the patient’s treatment plan.
The Primcyv composition works by blocking cyclin-dependent kinases, enzymes that help cancer cells grow and divide. By slowing down this process, the drug helps control disease progression.
Reading a Primcyv review can provide valuable insights into patient experiences, though results and side effects can differ from person to person. The Primcyv capsule price may vary depending on location, manufacturer, and pharmacy, so patients are advised to check with reliable suppliers for the latest cost details.
In summary, Primcyv for breast cancer is an important treatment option that helps manage advanced or metastatic stages of the disease, but it should only be used under the supervision of a qualified oncologist.
Uses
Primcyv uses are
- Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Primcyv 125mg Capsule works
Primcyv 125mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Primcyv 125mg Capsule with other drugs
Inform your doctor about all medications, including prescribed, over-the-counter, nutritional, or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of Primcyv 125mg Capsule with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. Certain medications may interact with the effectiveness of this drug.
Storage conditions
- Keep Primcyv 125mg Capsule out of sight and reach of children.
- Store at 20°C to 25°C.
How to take Primcyv 125mg Capsule
Take Primcyv 125mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice for Primcyv 125mg Capsule
Breast Feeding
It is not recommended to take Primcyv 125mg Capsule while breastfeeding as it is not known whether it passes into the breast milk.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Primcyv 125mg Capsule. Check with your doctor for advice.
Liver
Inform your physician if you have any liver disorders before taking Primcyv 125mg Capsule, as it should be used with caution in liver disorder patients.
Lungs
It is not unknown whether Primcyv 125mg Capsule can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Primcyv 125mg Capsule can cause tiredness. Avoid driving if you are unwell.
Pregnancy
It is not recommended to take Primcyv 125mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Primcyv side effects are
Serious:
- Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
- Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common:
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
Expert tips
-
Food interaction: Avoid grapefruit, grapefruit juice, and products containing St. John’s wort during Primcyv 125mg Capsule treatment.
-
Birth control (females): Use effective contraception during treatment and for at least 3 weeks after the final dose.
-
Birth control (males): Use effective contraception during treatment and for at least 14 weeks after the final dose.
-
Fertility concerns: Primcyv 125mg Capsule may reduce fertility – consult your doctor if you have concerns.
-
Monitoring: Your doctor may recommend regular blood tests to check if Primcyv 125mg Capsule affects your blood cells.
FAQs about Primcyv 125mg Capsule
Q1.
Is Primcyv 125mg Capsule targeted therapy?
Yes, Primcyv 125mg Capsule is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Do you lose hair on Primcyv 125mg Capsule?
Yes, Taking Primcyv 125mg Capsule can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q3.
Can children use Primcyv 125mg Capsule?
No, Primcyv 125mg Capsule is not recommended for adolescents and children under 18.
Q4.
Does Primcyv 125mg Capsule affect fertility?
Yes, Primcyv 125mg Capsule may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q5.
Does Primcyv 125mg Capsule affect blood cell count?
Primcyv 125mg Capsule might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Primcyv 125mg Capsule are advised.
Fact Box of Primcyv 125mg Capsule
|
Molecule name |
Palbociclib |
|
Therapeutic class |
Anti-Neoplastics |
|
Pharmacological class |
Cyclin-dependent kinase inhibitor |
|
Indications:
|
HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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