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Sazo 500mg Tablet
Last updated on 03 Sep 2026 | 07:37 AM (IST)
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MRP: ₹76.07
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Introduction to Sazo 500mg Tablet
Sazo 500mg Tablet contains an active component of Sulfasalazine. It is a medication commonly used to treat certain inflammatory conditions, particularly those that affect the gastrointestinal tract. It is used as a disease-modifying antirheumatic drug (DMARD) to help manage the symptoms of rheumatoid arthritis, a chronic inflammatory autoimmune disorder that primarily affects the joints. This means it helps manage symptoms and targets the underlying disease process, potentially slowing down disease progression and joint damage. It treats inflammatory bowel diseases like ulcerative colitis and Crohn's disease. This medication can help maintain remission in inflammatory bowel diseases, reducing the chances of flare-ups and improving the overall quality of life for individuals living with these chronic conditions.
If someone has a known hypersensitivity or allergic reaction to Sulfasalazine or any of its components, it's important to avoid using it. It should not be used in individuals with complete intestines or urinary tract obstruction. Avoid this medication in individuals with porphyria. Individuals with severe blood disorders such as aplastic anemia or agranulocytosis should not use it. It may be used in children under specific circumstances, such as when treating juvenile idiopathic arthritis or other inflammatory conditions. Close liver and kidney function monitoring is important, and any potential interactions with other medications should be assessed.
Uses of Sazo 500mg Tablet
Sazo 500mg Tablet is used in the following:
- Ulcerative colitis
- Crohn's disease
- Rheumatoid arthritis (RA) management
Therapeutic Effects of Sazo 500mg Tablet
Sulfasalazine works by reducing inflammation and suppressing the immune response that leads to the symptoms seen in these conditions. The 5-ASA component helps reduce inflammation in the gut, while the sulfapyridine component helps to deliver the 5-ASA to the desired site in the intestines.
Interaction of Sazo 500mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Sazo 500mg Tablet, reducing effectiveness by causing undesirable side effects.
More Information about Sazo 500mg Tablet
- Store at room temperature, between up to 20°C -25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Sazo 500mg Tablet
Sazo 500mg Tablet is typically administered orally in the form of tablets or capsules. It is important to follow your healthcare provider's instructions on how to take the medication.
Safety Advice for Sazo 500mg Tablet
Breast Feeding
Sazo 500mg Tablet can be excreted in breast milk. Consult your healthcare provider before breastfeeding while taking this medication.
Alcohol
Alcohol consumption can potentially increase the risk of side effects, such as dizziness or drowsiness, when taking Sazo 500mg Tablet so it not safe to take alcohol while using this medication.
Liver
Individuals with severe liver impairment should consult a healthcare provider before taking Sazo 500mg Tablet as liver function can affect the metabolism and elimination of this medication from the body.
Lungs
Inform your healthcare provider if you have respiratory symptoms before taking Sazo 500mg Tablet.
Driving
It is not safe to take Sazo 500mg Tablet while driving as it can cause dizziness or drowsiness.
Pregnancy
It is important to discuss your pregnancy status with your healthcare provider before starting Sazo 500mg Tablet.
Side Effects of Sazo 500mg Tablet
Sazo 500mg Tablet causes some side effects like all medications, although not everyone will experience them.
Serious
- Allergic reactions
- Liver problems
- Blood disorders
- Lung issues
- Stevens-Johnson syndrome
Common
- Nausea and vomiting
- Headache
- Rash
- Loss of appetite
- Abdominal discomfort
- Urinary changes
- Fever
- Joint pain
Word of Advice
Allergic reactions, liver problems, blood disorders, and lung issues are serious concerns that require immediate medical attention if experienced. Monitoring liver and kidney function is important, and individuals with kidney issues should use Sazo 500mg Tablet cautiously. Gastrointestinal discomfort, sensitivity to sunlight, and potential interactions with alcohol and certain medications are common considerations. For those with diabetes, infections, or surgeries planned, consulting a healthcare provider is essential. Fertility concerns, eye examinations, and the risk of methemoglobinemia should also be discussed. Comprehensive monitoring, especially blood counts and organ function, is vital. Always follow your healthcare provider's guidance and openly communicate about your health history and concerns to ensure safe and effective use of medication.
FAQs about Sazo 500mg Tablet
Q1.
What should I do if I miss a dose of Sazo 500mg Tablet?
If you miss a dose, take it as soon as you remember. If it's close to the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Q2.
How long does it take for Sazo 500mg Tablet to start working?
The time it takes for Sazo 500mg Tablet to show noticeable effects can vary. It may take several weeks to months to experience the full benefits. Consult your doctor for specific expectations based on your condition.
Q3.
Can Sazo 500mg Tablet be taken with food?
Taking Sazo 500mg Tablet with food or after a meal can help reduce gastrointestinal discomfort, which is a common side effect.
Q4.
Can I stop taking Sazo 500mg Tablet if my symptoms improve?
No, it is important to follow your healthcare provider's instructions. Stopping Sazo 500mg Tablet suddenly could lead to disease recurrence or worsening symptoms. Always consult your doctor before making any changes to your medication regimen.
Q5.
Are there foods or substances I should avoid while on Sazo 500mg Tablet?
Avoid alcohol due to potential interactions. While there are no specific dietary restrictions, consult your doctor about any concerns you have regarding your diet while on Sazo 500mg Tablet.
Q6.
What are the common side effects of Sazo 500mg Tablet?
Common side effects include nausea, vomiting, headache, rash, loss of appetite, abdominal discomfort, and changes in urine colour.
Fact Box of Sazo 500mg Tablet
| Molecule name: Sulfasalazine | Therapeutic class: Anti-inflammatory Agent
|
| Pharmacological class: Sulfonamide Derivative | Indications: 1. Ulcerative colitis 2. Crohn's disease 3. Rheumatoid arthritis (RA) management |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Anti-inflammatory, antipyretic, and analgesic agents; pharmacotherapy of gout, 12th edition, 2011, 993.
- KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 212.
- Pfizer, Electronic medicines compendium (emc), [Revised on 10th Aug 2023] [ Accessed on 25th August 2023],https://www.medicines.org.uk/emc/product/3838/smpc#gref
- Pfizer, US Food and Drug Administration, [Revised on 2009] [ Accessed on 25th August], https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that experts, accurate and trustworthy, review. The information and contents of this website are for informational purposes only. They are not intended to substitute for professional medical advice, diagnosis, or treatment. Please seek your doctor's advice and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 03 Sep 2026 | 07:37 AM (IST)
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