• For patients in intensive care settings (sedation)
• For diagnostic or surgical procedures (awake sedation)

Sedeto 50mcg injection acts on alpha-2 adrenergic receptors, inhibits the release of a chemical substance called norepinephrine, and terminates the spread of pain signals in the brain, providing calm and relaxation. When given slowly at lower and moderate doses, it mainly targets one type of  alpha1 receptor, providing a soothing effect. However, at higher doses or when given quickly, it can affect both types of alpha1 and alpha2 receptors.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with sedeto 50mcg injection and cause undesirable side effects.

• Keep sedeto 50mcg injection out of sight and reach of children.
• Store at room temperature.

Sedeto 50mcg injection is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into your muscle (intramuscularly) for adults in the arm and children in the thigh. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. 

Serious:

• Chest pain

Common:

• Abnormal heart rate
• High or low blood pressure
• Change in breathing pattern
• High or low blood sugar
• Nausea, vomiting, dry mouth
• Restlessness
• Fever

Inform your healthcare provider about any symptoms occurring within 48 hours after the treatment with sedeto 50mcg injection injection, such as nervousness, agitation, headaches (associated with infusions lasting over 6 hours), weakness, confusion, excessive sweating, weight loss, abdominal pain, salt cravings, diarrhea, constipation, dizziness, or light-headedness promptly.

Adhere strictly to the directed safety measures provided by your healthcare provider. It is important to attend all scheduled appointments and follow-up visits to monitor the response to sedeto 50mcg injection treatment.

1. Orion Corporation, Electronic medicines compendium (EMC), [Revised on Jan 2021] [Accessed on Nov 2023], https://www.medicines.org.uk/emc/files/pil.4783.pdf
2. Hospira, Inc, US, Inc, US Food and Drug Administration (FDA), [Revised on June 2013] [Accessed on Nov 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021038s021lbl.pdf
3. KD Tripathi, Essentials of Medical Pharmacology, General Anaesthetics, 7th edition, 2013, 384.
4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, General Anaesthetics and Therapeutic gases, 12th edition, 2011, 548-549.