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Sedogest SR 450 Tablet
Last updated on 15 Jun 2026 | 09:32 AM (IST)
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Sedogest SR 450 Tablet
Salt Composition
URSODEOXYCHOLIC ACIDMarketer
LA RENON HEALTHCARE PVT LTD
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Substitutes
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Introduction
Sedogest SR 450mg tablet consists of the active ingredient Ursodeoxycholic acid. It belongs to the group of medicines called Hepatoprotective agents. It is prescribed for liver and biliary conditions in case of cystic fibrosis and primary biliary cholangitis. Primary biliary cholangitis is a liver disorder where improper bile drainage damages liver tissues. Cystic fibrosis is an inherited liver and bile duct disease where the mucus in the body toughens and leads to clogging and inflammation.Ā
Dont take this tablet if you are allergic to Ursodeoxycholic acid or any of the other ingredients of this medicine. Before starting this treatment, inform your doctor if you have an acute inflammation or non-functional gallbladder or a narrowing or blockage of the bile ducts and your history with gallbladder conditions. If you have a history of liver disease or obstruction in bile passage, your doctor may monitor your liver function every four weeks during the first three months of treatment. This monitoring would also enable early detection of acute live failure, especially in people with advanced primary biliary cholangitis.Ā
Before starting the treatment with Sedogest 450mg, notify your doctor if you have recently had surgery in any part of your intestine or hepatic encephalopathy (nervous system disorder caused by severe liver disorder) or if you have a liver bleeding disorder and any liver-related condition. Report to your doctor if you have any underlying kidney condition because there is limited information on the use of this tablet in patients with kidney disease. The common side effects of this tablet are pasty stool, diarrhea, rash, and abdominal pain. Sedogest SR 450 substitute includes Gestodene 450mg Tablet, Femodene 450mg Tablet, or Ovulen 450mg Tablet under a doctorās supervision. Sedogest SR 450 price varies by retailer and location. You can buy Sedogest SR 450 online at MrMed.
Uses
Sedogest SR 450 uses are:
Primary biliary cholangitis (PBC)
Cystic fibrosis (liver disease in children aged between 6 to 18 years)
Gallstone (not visible on plain X-ray)
How Sedogest SR 450mg Tablet Works
Sedogest SR 450mg works by reducing the production of cholesterol in the liver and increasing the secretion of bile. This helps to dissolve and prevent the formation of gallstones, as well as improve liver function in certain conditions.
Interaction of Sedogest SR 450mg Tablet with other drugs
Warfarin (Severe)
Sedogest may enhance the anticoagulant effect of Warfarin, increasing the risk of bleeding. Regular INR monitoring is recommended.Aspirin / NSAIDs (Moderate)
Concurrent use may increase the risk of stomach irritation, ulcers, or bleeding. Use with caution and under medical advice.Antidiabetic Medicines (Moderate)
Sedogest may alter blood sugar control when used with insulin or oral hypoglycemics. Monitor blood sugar levels regularly.ACE Inhibitors / ARBs (Moderate)
Combining with these blood pressure medicines may increase the risk of kidney problems. Regular kidney function monitoring is advised.Diuretics (Moderate)
Sedogest may reduce the effectiveness of certain diuretics and alter electrolyte balance. Consult your doctor before using together.
Storage Conditions
Keep Sedogest SR 450mg out of sight and reach of children.
Store in a cool, dry place, away from direct heat and light.
Store below 25oC
Do not refrigerate or freeze.
How to take Sedogest SR 450mg Tablet
The Sedogest SR 450mg tablet is taken after a meal with a glass of milk or a small snack Avoid chewing, breaking, or crushing it. Your physician will choose the Sedogest SR 450 dosage based on your medical condition because it differs for each person.Ā
Safety Advice for Sedogest 450mg Tablet
Breast Feeding
Tell your doctor if you are breastfeeding or about to start breastfeeding because Sedogest SR 450mg may pass into the human breast milk. Your physician shall prescribe this tablet only if it is essential.
Alcohol
It is unsafe to consume alcohol because it can cause excessive drowsiness. Consult your doctor for more information.
Liver
Inform your physician before taking the Sedogest SR 450mg tablet if you have a problem in the liver, gall bladder, or bile duct. your doctor might advise you for frequent liver examinations and tests during the treatment. Consult your doctor for more information.Ā
Lungs
It is unknown whether taking a Sedogest SR 450mg tablet is safe. Notify your doctor if you have or have had any history of lung conditionĀ Please speak with your physician.
Driving
There is no interaction with the driving ability or the ability to operate machines. Contact your doctor for more concerns.Ā
Pregnancy
Before starting the treatment, inform your doctor if you are pregnant or think you may be pregnant or are planning to have a baby because your physician shall prescribe Sedogest SR 450mg only if it is essential. Consult your doctor for more information.
Side Effects
Sedogest SR 450mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Pasty stool
Diarrhea
Rash
Abdominal pain
Expert tips
Avoid planning for pregnancy while taking Sedogest 450mg and discuss effective contraception methods with your doctor.
Consult your doctor immediately if you experience any side effects from the medication.
Inform your doctor about any other medications taken before starting Sedogest 450mg, as they may reduce effectiveness or cause side effects.
Disclose any history of liver problems or other medical conditions related to the gallbladder to your doctor.
Notify your doctor if you have had intestinal surgery before starting this medication.
FAQs about Sedogest 450mg Tablet
Q1.
How long do these side effects of Sedogest SR 450mg last?Ā
The duration of the Sedogest SR 450mg side effects may vary from person to person. In most cases, these side effects are mild and temporary and go away within a few days to a week.
Q2.
Who is at risk of experiencing side effects from Sedogest SR 450mg?
People with a history of liver or gallbladder problems, or those with allergies to Sedogest 450mg or any of its ingredients, may be at a higher risk of experiencing side effects.
Q3.
Can Sedogest SR 450mg cause infertility in men or women?Ā
There is currently no evidence to suggest that Sedogest SR 450mg causes infertility in men or women. Consult your doctor for more fertility concerns.Ā
Q4.
Can Sedogest SR 450mg affect a developing fetus if I become pregnant while taking it?Ā
The safety of Sedogest SR 450mg during pregnancy has not been established. If you become pregnant while taking Sedogest SR 450mg, speak to your doctor about the potential risks and benefits of continuing treatment.
Q5.
How is Sedogest SR 450mg taken?
Sedogest SR 450mg is typically taken orally as a tablet or capsule. The dosage and frequency of the medication will depend on the specific condition being treated and the patient's needs. Your physician will choose the dosage.Ā
Fact Box
Molecule name: Ursodeoxycholic acid | Therapeutic class: Liver disease |
Pharmacological class: Hepatoprotective agentsĀ | Indication:Ā 1. Primary biliary cholangitis (PBC) 2. Cystic fibrosis (liver disease in children aged between 6 to 18 years) 3. Gallstone (not visible on plain X-ray)Ā |
References
- Glenmark Pharmaceuticals, Electronic Medicines Compendium (EMC), [Revised on Mar 2019] [Accessed on 09h Apr 2023] https://www.medicines.org.uk/emc/files/pil.10064.pdfĀ
- Anthony Gamboa et al., The Therapeutic Role of Ursodeoxycholic Acid in Digestive Diseases, Annals of Gastroenterology & Hepatology, 2011, [Accessed on 09h Apr 2023] Ā Ā https://www.researchgate.net/publication/265075464_The_Therapeutic_Role_of_Ursodeoxycholic_Acid_in_Digestive_DiseasesĀ
Disclaimer
MrMedās primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Aswini Priya Velmurugan
PG in Biotechnology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 15 Jun 2026 | 09:32 AM (IST)
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