Semasize Plus 2.4mg Pen Injection may be prescribed for:

• Chronic weight management: It may be used with a reduced-calorie diet and increased physical activity in eligible adults who need long-term weight management.

• Type 2 diabetes mellitus: Semaglutide may be prescribed as part of a treatment plan to improve blood glucose control in adults with type 2 diabetes.

The appropriate dose and duration depend on the individual's medical condition and treatment response. Do not start or change the dose without medical advice.

Semaglutide acts similarly to a naturally occurring hormone called GLP-1. It helps the pancreas release insulin when blood glucose levels are elevated and reduces the release of glucagon, which helps lower blood glucose.

It also slows the movement of food through the stomach and acts on areas of the brain involved in appetite regulation. These effects can help increase fullness, reduce food intake, and support weight loss when used with diet and physical activity.

Tell your doctor about all medicines you take before starting Semasize Plus 2.4mg Pen Injection.

• Insulin and sulfonylureas: Using Semaglutide with these medicines may increase the risk of low blood sugar. Your doctor may adjust their dose.

• Medicines taken by mouth: Semaglutide can delay gastric emptying and may affect the absorption of some oral medicines.

• Other GLP-1 receptor agonists: Do not use Semaglutide with another Semaglutide-containing medicine or another GLP-1 receptor agonist unless specifically advised by your doctor.

• Medicines for diabetes: Tell your doctor about all diabetes medicines you use so your treatment can be adjusted safely.

• Store the unopened pen in a refrigerator at 2°C to 8°C.

• Do not freeze.

• Keep the pen away from direct light.

• Keep out of reach of children.

• Follow the storage instructions printed on the product packaging for the pen after first use.

The Semasize Plus 2.4mg packaging specifies refrigeration at 2°C to 8°C and states that the product should not be frozen.

Semasize Plus 2.4mg Pen Injection is given under the skin once a week, exactly as prescribed by your doctor. It can be injected into the abdomen, thigh, or upper arm. Rotate injection sites when possible. 

The product is supplied as a multi-dose disposable pen. The pack contains one pen, four needles, and four alcohol swabs, with one pen providing four doses of 2.4 mg. 

Your doctor or healthcare professional should show you how to use the pen before you administer your first dose. Do not share the pen or needles with another person, even if the needle has been changed.

Common side effects of Semasize Plus 2.4mg Pen Injection include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

• Decreased appetite

• Indigestion

• Headache

• Fatigue

These effects are more likely when treatment is started or the dose is increased and may improve as the body adjusts.

Seek medical attention if you develop severe or persistent abdominal pain, especially if it spreads to the back, as this may indicate pancreatitis. People with diabetes who have a history of diabetic retinopathy should also be monitored for worsening eye-related complications. 

• Use Semasize Plus 2.4mg Pen Injection once weekly on the same day, unless your doctor changes the schedule.

• Follow the prescribed dose. Do not increase the dose to achieve faster weight loss or better blood sugar control.

• Eat smaller meals and avoid eating too quickly if nausea or fullness occurs.

• Drink enough fluids, especially if vomiting or diarrhoea occurs.

• Follow a balanced diet and remain physically active as advised by your healthcare professional.

• Tell your doctor if you have a history of pancreatitis, diabetic retinopathy, gallbladder problems, or severe gastrointestinal disease.

• If you are using insulin or a sulfonylurea, know the symptoms of low blood sugar and follow your doctor's advice on monitoring.

• Never share your pen or needles with another person.