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Sevasor 400 Tablet
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction
Sevasor 400 Tablet contains an active ingredient called Sevelamer. It belongs to the medication class known as phosphate binders. It is used to manage hyperphosphatemia (high blood phosphate levels) in adult patients undergoing dialysis (hemodialysis or peritoneal dialysis) and patients with chronic kidney disease who have elevated serum phosphorus levels. It should be used with other treatments, such as calcium supplements and vitamin D, to prevent bone disease. High blood phosphorus levels can cause calcification, where hard deposits form and stiffen blood vessels, affecting blood flow.
Do not consume Sevasor 400 mg if you are allergic to Sevelamer or any of its ingredients in the medication. Avoid consuming this medicine if you have low levels of phosphate and bowel obstruction. Before taking this medicine, notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or are breastfeeding. Before starting treatment, let your doctor know if you have trouble swallowing or if your stomach and bowel have problems moving food.
Also, inform your doctor if you currently have bowel inflammation or have had major stomach or bowel surgery. Sevasor 400 Tablet is not recommended for children under six years old due to the lack of studies on its safety and effectiveness in that age group. If your doctor has advised you about a sugar intolerance, please consult your doctor before taking this medication, as it contains lactose.
Uses
- Manage hyperphosphatemia (high blood phosphate levels)
-
Prevent bone disease in combination with calcium and vitamin D supplements.
How Sevasor 400 Tablet works
Sevasor 400 Tablet functions by binding phosphate from ingested food within the digestive tract, thereby reducing phosphorus levels in the bloodstream.
Interaction of Sevasor 400 Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Sevasor 400 Tablet and can cause undesirable side effects.
Storage conditions
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Keep out of sight and reach of pets and children.
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Do not freeze the medicine.
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Do not store above 30°C.
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Always check the expiry date before consuming it.
How to take Sevasor 400 Tablet
Take the Sevasor 400 Tablet as your physician advises. Take medicine at a fixed time. It is given based on the level of phosphate in the blood. Usually, it is given three times a day with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Do not stop taking the tablet unless your doctor advises you to stop.
Safety Advices
Pregnancy
It is unknown whether Sevasor 400 Tablet is harmful to the unborn baby. Notify your healthcare professional if you are pregnant, planning to get pregnant or think you may be pregnant. The potential benefits and risks of the medicine should be carefully assessed.
Breast Feeding
It is unknown whether Sevasor 400 Tablet is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information
Lungs
It is unknown whether Sevasor 400 Tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
It is unknown whether Sevasor 400 Tablet is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Alcohol
It is unknown whether consuming alcohol while taking Sevasor 400 Tablet is safe. Please speak with your physician.
Driving
Sevasor 400 Tablet carbonate is not expected to impair your ability to drive or operate machinery. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
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Intestine or bowel obstruction
Common
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Nausea
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Vomiting
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Abdominal pain
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Diarrhea
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Flatulence
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Indigestion
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Constipation.
Expert tips
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Inform your doctor about all your existing medical conditions before starting treatment.
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Do not stop taking the medicine unless your doctor specifically advises you to do so.
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Do not take a double dose to make up for a missed or forgotten dose.
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Notify your doctor immediately if you experience any serious or unusual side effects.
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Contact your doctor for any additional information or guidance regarding your treatment.
FAQs
Q1.
What should I do to reduce the side effects of Sevasor 400 Tablet?
To manage the side effects of Sevasor 400 Tablet, follow the prescribed dosage, and report side effects promptly. Stay hydrated, avoid fatty foods and dairy products. Consult your doctor before taking Sevasor 400 Tablet with other medications to optimize its effectiveness and reduce side effects. Maintain a healthy lifestyle by following a balanced diet and attending follow-up appointments.
Q2.
What additional supplements might be prescribed by my doctor while taking Sevasor 400 Tablet?
Supplements such as calcium, vitamin D, and possibly vitamins A, E, K, and folic acid supplements may be prescribed by your doctor in combination with Sevasor 400 Tablet.
Q3.
What are the side effects of Sevasor 400 Tablet?
Common side effects of Sevasor 400 Tablet include nausea, vomiting, abdominal pain, diarrhea, flatulence, indigestion, and constipation. It is crucial to consult your doctor for any concerns or persistent side effects.
Q4.
Can Sevasor 400 Tablet be taken during pregnancy or while breastfeeding?
Information regarding the usage of Sevasor 400 Tablet during pregnancy and breastfeeding is unknown. So, it is recommended to get healthcare professionals' advice before consuming the medicine. The potential benefits and risks of the medicine should be carefully assessed.
Q5.
Why should Sevasor 400 Tablet be taken with food?
Sevasor 400 Tablet is more effective at binding to phosphorus when it is taken with food. Taking this medicine without food can increase your risk of side effects.
Fact Box
|
Molecule Name |
Sevelamer |
|
Therapeutic class |
PO4 scavengers |
|
Pharmacological class |
Phosphate binders |
|
Indications |
1. Manage hyperphosphatemia (high blood phosphate levels) 2. Prevent bone disease in combination with calcium and vitamin D supplements. |
References
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Zentiva Pharma UK Limited; Electronic Medicines Compendium (EMC); [Revised on Aug 2019] [Accessed on 19th July 2023], https://www.medicines.org.uk/emc/files/pil.8679.pdf
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Genzyme Ireland Ltd; US Food and Drug Administration; [Revised on April 2019] [Accessed on 19th July 2023], label (fda.gov)
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J. Goddard, A.N. Turner, Kidney and urinary tract disease, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 461-523.
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Daniel D. Bikle, Agents That Affect Bone Mineral Homeostasis, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 772-791.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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