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Sevlaren 400mg Tablet 15's
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction to Sevlaren 400mg Tablet 15's
Sevlaren 400mg Tablet 15's contains an active ingredient called Sevelamer. It belongs to the medication class known as phosphate binders. It is used to manage hyperphosphatemia (high blood phosphate levels) in adult patients undergoing dialysis (hemodialysis or peritoneal dialysis) and patients with chronic kidney disease who have elevated serum phosphorus levels. It should be used with other treatments, such as calcium supplements and vitamin D, to prevent bone disease. High blood phosphorus levels can cause calcification, where hard deposits form and stiffen blood vessels, affecting blood flow.
Do not consume Sevlaren 400mg Tablet 15's if you are allergic to Sevelamer or any of its ingredients in the medication. Avoid consuming this medicine if you have low levels of phosphate and bowel obstruction. Before taking this medicine, notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or are breastfeeding. Before starting treatment, let your doctor know if you have trouble swallowing or if your stomach and bowel have problems moving food.
Also, inform your doctor if you currently have bowel inflammation or have had major stomach or bowel surgery. Sevlaren 400mg Tablet 15's is not recommended for children under six years old due to the lack of studies on its safety and effectiveness in that age group. If your doctor has advised you about a sugar intolerance, please consult your doctor before taking this medication, as it contains lactose.
Uses of Sevlaren 400mg Tablet 15's
Sevlaren 400mg Tablet 15's is used in the treatment of the following:
- Manage hyperphosphatemia (high blood phosphate levels)
- Prevent bone disease in combination with calcium and vitamin D supplements.
Therapeutic Effects of Sevlaren 400mg Tablet 15's
Sevlaren 400mg Tablet 15's functions by binding phosphate from ingested food within the digestive tract, thereby reducing phosphorus levels in the bloodstream.
Interaction of Sevlaren 400mg Tablet 15's with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Sevlaren 400mg Tablet 15's and can cause undesirable side effects.
More Information about Sevlaren 400mg Tablet 15's
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Sevlaren 400mg Tablet 15's
Take the Sevlaren 400mg Tablet 15's as your physician advises. Take medicine at a fixed time. It is given based on the level of phosphate in the blood. Usually, it is given three times a day with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Do not stop the medicine unless your doctor advises.
Safety Advice for Sevlaren 400mg Tablet 15's
Breast Feeding
It is unknown whether Sevlaren 400mg Tablet 15's is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Alcohol
It is unknown whether consuming alcohol while taking Sevlaren 400mg Tablet 15's is safe. Please speak with your physician.
Liver
It is unknown whether Sevlaren 400mg Tablet 15's is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Lungs
It is unknown whether Sevlaren 400mg Tablet 15's is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Sevlaren 400mg Tablet 15's carbonate is not expected to impair your ability to drive or operate machinery. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
It is unknown whether Sevlaren 400mg Tablet 15's is harmful to the unborn baby. Notify your healthcare professional if you are pregnant, planning to get pregnant or think you may be pregnant. The potential benefits and risks of the medicine should be carefully assessed.
Side Effects of Sevlaren 400mg Tablet 15's
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of Sevlaren 400mg Tablet 15's:
- Intestine or bowel obstruction
Common side effects of Sevlaren 400mg Tablet 15's:
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Flatulence
- Indigestion
- Constipation
Word of Advice
If you experience severe abdominal pain, stomach or intestine issues, or notice blood in your stool while taking this medicine, it could be a sign of serious inflammatory bowel disease caused by Sevlaren 400mg Tablet 15's. Contact your doctor immediately to discuss whether you should continue the treatment or not. Notify your doctor if you experience any serious side effects to avoid the risk of certain conditions. Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Contact your doctor for more information.
FAQs about Sevlaren 400mg Tablet 15's
Q1.
How to manage the side effects of Sevlaren 400mg Tablet 15's?
To manage the side effects of Sevlaren 400mg Tablet 15's, follow the prescribed dosage, and report side effects promptly. Stay hydrated, avoid fatty foods and dairy products. Consult your doctor before taking Sevlaren 400mg Tablet 15's with other medications to optimize its effectiveness and reduce side effects. Maintain a healthy lifestyle by following a balanced diet and attending follow-up appointments.
Q2.
Why should Sevlaren 400mg Tablet 15's be taken with food?
Sevlaren 400mg Tablet 15's is more effective at binding to phosphorus when it is taken with food. Taking Sevlaren 400mg Tablet 15's without food can increase your risk of side effects.
Q3.
What additional supplements might be prescribed by my doctor while taking Sevlaren 400mg Tablet 15's?
Supplements such as calcium, vitamin D, and possibly vitamins A, E, K, and folic acid supplements may be prescribed by your doctor in combination with Sevlaren 400mg Tablet 15's.
Fact Box of Sevlaren 400mg Tablet 15's
| Molecule Name: Sevelamer | Therapeutic class: PO4 scavengers |
| Pharmacological class: Phosphate binders | Indications: 1. Manage hyperphosphatemia (high blood phosphate levels) 2. Prevent bone disease in combination with calcium and vitamin D supplements. |
References
1. Zentiva Pharma UK Limited; Electronic Medicines Compendium (EMC); [Revised on Aug 2019] [Accessed on 19th July 2023], https://www.medicines.org.uk/emc/files/pil.8679.pdf
2. Genzyme Ireland Ltd; US Food and Drug Administration; [Revised on April 2019] [Accessed on 19th July 2023], label (fda.gov)
3. J. Goddard, A.N. Turner, Kidney and urinary tract disease, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 461-523.
4. Daniel D. Bikle, Agents That Affect Bone Mineral Homeostasis, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 772-791.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get accurate and trustworthy information that is reviewed by experts. The contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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