SIMULECT 20MG INJECTION

Introduction:

Simulect 20mg Injection is an immunosuppressant medication containing the active constituent called basiliximab. It helps prevent organ rejection in people who are having a kidney transplant. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ. 

Talk to your physician if you have previously received a transplant, have any diseases or allergic conditions, or are about to receive any vaccinations before taking Simulect 20mg Injection. Use effective birth control during the treatment and for at least four months after the last dose. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medication.

Uses of Simulect 20mg Injection:

• Prevents rejection of kidney transplant

How Simulect 20mg Injection works:

Simulect 20mg Injection decreases the activity of your body’s immune system and prevents it from attacking the transplanted organ.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Simulect 20mg Injection out of sight and reach of children. 
• Store in a refrigerator at 2°C to 8°C.

References:

1. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (emc), [ Revised on Sept 2021] [ Accessed on 18th Dec 2021], https://www.medicines.org.uk/emc/files/pil.7834.pdf
2. Xuping Yao et al; Basiliximab induction in kidney transplantation with donation after cardiac death donors; Experimental and Therapeutic medicine; Published on 08/04/2016; Accessed on 18/12/2021; https://www.spandidos-publications.com/10.3892/etm.2016.3238
3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1017.
4. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 879,884.

How to use Simulect 20mg Injection:

It will be given to you by a health care professional.

Safety advice:

Pregnancy:

Simulect 20mg Injection is contraindicated in pregnant patients. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Breastfeeding:

Simulect 20mg Injection is contraindicated in breastfeeding patients. You need to tell your doctor if you are breastfeeding before taking this medicine.

Others:

• Inform your physician if you have previously received a transplant, have any diseases or allergic conditions, or are about to receive any vaccinations before taking Simulect 20mg Injection.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Severe allergic reactions (swelling of face, tongue, or lips, difficulty in breathing, fast heartbeat, dizziness, decreased urine output)

Common:

• Constipation, diarrhea
• Weigh gain
• Nausea
• Headache, pain
• High blood pressure
• Anemia
• Infections
• Runny or blocked nose, fever
• Excessive growth of normal hair