Quick Summary
Sovihep V Tablet
Last updated on 08 Jun 2026 | 06:13 AM (IST)
₹5775
MRP: ₹18046.82
(You Save ₹12271.82)
28 TABLET(s) IN A BOTTLE
Sovihep V Tablet is a prescription antiviral medicine used to treat chronic hepatitis C infection. It is a fixed-dose combination that works by blocking viral replication, helping eliminate the virus from the body. Sovihep V is taken under medical supervision as part of a structured hepatitis C treatment regimen.
68% OFF
₹5775
MRP: ₹18,046.82
Inclusive of all taxes
68% Off
Dispatch: Today
Care delivered without the wait. Your order is prioritized for rapid dispatch to ensure it reaches your doorstep on time.
Substitutes
Velasof Tablet
HETERO HEALTHCA...
₹ 154.04/tablet
25% cheaper
Velpanat Tablet
NATCO PHARMA LT...
₹ 184.18/tablet
10% cheaper
Sofocure V Tablet
EMCURE PHARMACE...
₹ 192.54/tablet
6% cheaper
Resof Total Tablet
DR REDDY'S LABO...
₹ 193.36/tablet
6% cheaper
Introduction
Sovihep V tablet contains the active components Sofosbuvir and Velpatasvir. It is used to treat chronic hepatitis C. Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). The treatment duration is often shorter than older treatment regimens. The duration can vary depending on factors such as HCV genotype, previous treatment history, and the presence of liver cirrhosis. Successful treatment with Sovihep V tablet can significantly reduce liver inflammation and fibrosis caused by HCV infection. By achieving viral eradication, the risk of developing liver cirrhosis, liver failure, and hepatocellular carcinoma (a type of liver cancer) can be substantially reduced.
If you have a known allergy or hypersensitivity to Sovihep V tablets or any of the components of the medication, you should not take it. The safety and efficacy of sofosbuvir and velpatasvir combination therapy have not been established in children under 18. Its use in the pediatric population is currently limited. It is recommended to use alternative treatment options or adjust the dosage in these cases. Sovihep V price is differ from vendor to vendor. Sovihep V substitute Sofosbuvir 400 mg and Velpatasvir 100 mg. Sovihep V Tablet price varies by retailer and location. You can buy Sovihep V Tablet online.
Uses
Sovihep V Tablet uses:
To treat chronic hepatitis C (HCV) infection.
How Sovihep V Tablet Works
Sofosbuvir is a direct-acting antiviral drug (DAA) that inhibits the replication of the HCV virus by targeting a specific protein necessary for viral replication. Velpatasvir is also a DAA that works by blocking the action of another protein involved in the HCV replication process.
Interaction of Sovihep V Tablet with other drugs
Amiodarone (Life threatening)
Using amiodarone with sofosbuvir containing regimens can trigger severe, sudden bradycardia. This combination is avoided unless absolutely necessary, and continuous heart monitoring is mandatory if used.
Rifampicin and Other Strong Enzyme Inducers (Severe)
Drugs like rifampicin, carbamazepine, or phenytoin can sharply reduce antiviral levels, making the treatment ineffective. Such combinations are strictly discouraged.
Atorvastatin and Other Statins (Severe)
Velpatasvir can raise statin concentrations, increasing the risk of muscle pain or serious muscle injury. Doctors may reduce the statin dose or switch to a safer option.
Proton Pump Inhibitors such as Omeprazole (Moderate)
PPIs can lower velpatasvir absorption by altering stomach acidity. If both are needed, spacing doses and using the lowest PPI strength is advised.
Tenofovir Based HIV Medicines (Moderate)
Co-administration may increase tenofovir exposure, raising the risk of kidney strain. Kidney function needs regular monitoring.
Storage Conditions
Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
Keep away from moisture, heat, and light.
It should not be frozen.
Keep away from children and pets.
How to consume Sovihep V Tablet
Read the instructions carefully before taking tab Sovihep V. Take Sovihep V dosage as directed by your doctor. Take it with or without food. This will help to improve absorption. If you experience side effects, stop taking them and talk to your doctor.
Safety Advice for Sovihep V Tablet
Breast Feeding
There is limited information about the safety of Sovihep V tablet in breastfeeding. If you are pregnant or planning to become one, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.
Alcohol
It is generally recommended to avoid alcohol consumption during hepatitis C treatment, including Sovihep V tablet. Alcohol can potentially worsen liver damage and interfere with the effectiveness of the medication. It is best to consult with your healthcare provider regarding alcohol consumption during treatment.
Liver
If you have a chronic lung disease, talk to your doctor about the risks and benefits. They can help you decide if Sovihep V tablet is right for you.
Lungs
If you have a chronic lung disease and are considering taking Sovihep V tablet, talk to your doctor about the risks and benefits.
Driving
Common side effects of Sovihep V tablet include headache, fatigue, and dizziness. Suppose you experience any of these side effects or other symptoms that may impair your ability to drive safely. In that case, you should refrain from driving or operating heavy machinery until you feel fully alert and capable.
Pregnancy
There is limited information about the safety of Sovihep V tablets in pregnancy. If you are pregnant and considering taking them, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.
Side Effects
Sovihep V Tablet side effects like all medications, although not everyone will experience them.
Serious:
Hepatitis B reactivation
Severe allergic reactions
Common:
Headache
Fatigue
Nausea
Insomnia
Diarrhea
Itching (pruritus)
Decreased appetite
Muscle or joint pain
Rash
Dizziness
Expert tips
Screen for hepatitis B infection before starting treatment due to the risk of HBV reactivation, and monitor liver function and HBV DNA during and after therapy.
Inform your doctor about all current medications to avoid drug interactions, especially with amiodarone, which may cause severe bradycardia when used together.
Dose adjustments are required in severe renal impairment or end-stage renal disease.
Patients with a history of psychiatric disorders should be monitored for changes in mental health during treatment.
Discuss pregnancy and breastfeeding risks with your healthcare provider, and use caution in special groups such as HIV or HCV co-infected patients and liver transplant recipients.
FAQs about Sovihep V Tablet
Q1.
Can Sovihep V tablet cure hepatitis C in individuals with advanced liver disease or cirrhosis?
Sovihep tablet has shown efficacy in treating hepatitis C in individuals with advanced liver disease or compensated cirrhosis. However, the response rate may vary, and close monitoring of liver function is important during and after treatment.
Q2.
Is it necessary to undergo regular blood tests while on Sovihep V tablet treatment?
Yes, regular blood tests are typically conducted during Sovihep V tablet treatment to monitor liver function, viral load, and treatment response. These tests help assess the effectiveness of the medication and ensure patient safety.
Q3.
Can Sovihep V tablet be used in patients with kidney disease?
Sovihep V uses in patients with mild to moderate kidney impairment without dose adjustment. However, patients with severe renal impairment or end-stage renal disease may require dose adjustments or alternative treatment options. It is important to discuss your kidney function with your healthcare provider to determine the most appropriate treatment plan.
Q4.
Can Sovihep V tablet be used in patients with HIV co-infection?
Sovihep V tablet is effective and safe in individuals with both hepatitis C and HIV co-infection. However, it is important to coordinate treatment with both infectious disease and HIV specialists to ensure proper management of both conditions.
Q5.
Can Sovihep V tablet cause weight gain or loss?
Weight gain or loss is not commonly reported as a side effect of Sovihep V tablet. However, individual responses to medication can vary. If you experience any unexplained or concerning changes in weight during treatment, it is recommended to consult your healthcare provider for further evaluation.
Q6.
Can Sovihep V tablet be used in patients with a history of liver transplantation?
Sovihep V tablet can be used in patients with a history of liver transplantation who have recurrent hepatitis C. However, individual patient factors and the specific post-transplantation period must be considered. Consultation with a transplant hepatologist or specialist is recommended to determine the most appropriate treatment approach.
Q7.
Can Sovihep V tablet cause any serious side effects?
While Sovihep V tablet is generally well-tolerated, like any medication, it can potentially cause side effects. Common side effects include headache, fatigue, nausea, and insomnia. Serious side effects are rare but can include severe allergic reactions, changes in heart rate, and liver problems. It is important to discuss any concerns or potential side effects with your healthcare provider, who can provide further information and guidance based on your specific situation.
Fact Box of Sovihep V Tablet
Molecule name: | Sofosbuvir, Velpatasvir |
Therapeutic class: | Antiviral |
Pharmacological class: | 1. Sofosbuvir: Nucleotide analog 2. Velpatasvir: Direct-acting antiviral (DAA) |
Indications: | Chronic hepatitis C (HCV) infection |
References
- Gilead Sciences Ltd, Electronic medicines compendium (EMC), [Revised on Jan 2021] [ Accessed on 24th June 2023], https://www.medicines.org.uk/emc/files/pil.7294.pdf
- Gilead Sciences Inc, US Food and Drug Administration, [Revised on Aug 2017] [Accessed on 24th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208341s007lbl.pdf
- Sarah L Greig; Sofosbuvir/Velpatasvir: A Review in Chronic Hepatitis C; Drugs; [Published on 24th June 2023]; [Accessed on 24th June 2023]; https://pubmed.ncbi.nlm.nih.gov/27730529/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
Did you find this information helpful?
Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 08 Jun 2026 | 06:13 AM (IST)
Want to know more?
Read Our Editorial Policy
