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Spnib 50mg Tablet
Last updated on 31 Mar 2026 | 09:31 AM (IST)
ā¹3153
MRP: ā¹3503.44
(You Save ā¹350.44)
60 TABLET(s) IN A BOTTLE
Spnib 50 mg Tablet is a prescription anticancer medicine used in the treatment of certain cancers such as advanced kidney cancer and gastrointestinal stromal tumors (GIST), as advised by an oncologist. It contains sunitinib, a targeted therapy that works by blocking proteins involved in tumor growth and the formation of blood vessels that supply cancer cells. Spnib is taken under strict medical supervision as part of a personalized cancer treatment plan.
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Introduction
Spnib 50mg Tablet contains the active ingredient Dasatinib. It is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia (CML). This medicine is also used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia in the chronic phase and Ph+ acute lymphoblastic leukemia (ALL) in patients who are resistant to other therapies.
Chronic Myeloid Leukemia is a form of blood cancer where the body produces too many white blood cells due to changes in the Philadelphia chromosome. On the other hand, Acute Lymphoblastic Leukemia is a blood cancer most common in children, where lymphocytes multiply abnormally fast and survive longer than usual.
The Spnib 50 mg tablet price and Spnib 50 mg price in India can differ depending on the medical store, location, and availability. Patients looking for convenience can also buy Spnib 50 mg tablet online from trusted and licensed medical platforms with a valid prescription.
The primary Spnib 50 mg uses include treating CML and ALL effectively. Your doctor will determine the right Spnib 50 mg dosage according to your health condition, treatment stage, and response to the medicine.
This medicine is produced by a reliable Spnib 50 mg manufacturer, and the Spnib 50 mg tablet composition includes Dasatinib as the active ingredient. For patients in India, Spnib 50 mg availability in India ensures access through both local pharmacies and online suppliers.
Uses
SpnibĀ 50mgĀ tablet is indicated for the following conditions
- Children and adults with chronic myeloid leukemia.
- Adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) with resistance to prior therapy.
How Spnib 50mg Tablet works
SpnibĀ 50mgĀ tablet works by preventing the abnormal protein from signaling the growth of cancer cells. This aids in preventing or reducing the spread of cancer cells.
Interaction of Spnib 50mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with SpnibĀ 50mgĀ tablet and can cause undesirable side effects.Ā
Storage conditions
- Store protected from light at a temperature not exceeding 30c.
How to take Spnib 50mg Tablet
Take the tablet with or without food at the same time each day. Do not break, crush or chew the tablet. Your doctor will decide the dose and frequency of SpnibĀ 50mgĀ tablet administration based on your disease severity and other factors. Do not stop taking the tablet without consulting your healthcare professional.Ā
Safety Advice for Spnib 50mg Tablet
Breast Feeding
It is not recommended to breastfeed while taking SpnibĀ 50mgĀ tablet as it is unknown whether this medication passes into breast milk. You should not breastfeed during treatment and for 2 weeks after your final dose.
Alcohol
It is not known whether it is safe to consume alcohol with SpnibĀ 50mgĀ tablet. Consult your doctor for advice.
Liver
Inform your physician before starting this treatment if you have liver diseases. Your physician will prescribe a dose accordingly.
Lungs
It is unknown whether SpnibĀ 50mg tablet is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment.
Driving
Avoid driving or using machinery if you experience symptoms like breathlessness or altered consciousness.
Pregnancy
SpnibĀ 50mgĀ tablet is not recommended during pregnancy unless necessary. Your physician will discuss the potential risk during pregnancy. Women should use effective birth control during treatment and 30 days after the final dose.Ā
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. spnib 50 mg side effects areĀ
Serious
- Unusual bleeding or bruising
- Rapid heart rate
- Changes in consciousness or speech
- Breathlessness and swelling all over the body
- Fever or signs of infection
- Fluid retention
- Heart problems
- Myelosuppression
- Severe allergic reaction
Common
- Diarrhea
- Headache
- Cough
- Rash
- Nausea, tiredness, vomiting
- Muscle pain, weakness
- Low appetite
- High or low BP
Expert Tips
-
Use effective contraceptives for both men and women while taking Spnib 50mg tablet and for 30 days after the last dose.
-
Monitor your blood pressure regularly during treatment.
-
Inform your doctor immediately if you notice blood in your urine or stools.
-
If you are taking an antacid, take it 2 hours before or 2 hours after taking this tablet.
FAQs about Spnib 50mg Tablet
Q1.
Can children use SpnibĀ 50mgĀ tablet?
SpnibĀ 50mgĀ tablet is not recommended for children under the age of one.Ā
Q2.
Can SpnibĀ 50mgĀ tablet cause hair loss?
Yes, Hair loss is one of the common side effects of taking Dosatinib. Consult your doctor for advice if these side effects disturb or persist.Ā
Q3.
Is SpnibĀ 50mgĀ tablet a chemotherapy drug?
Yes, SpnibĀ 50mgĀ tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitors.Ā
Q4.
Should SpnibĀ 50mgĀ Ā tablet be taken with food?
Yes, SpnibĀ 50mgĀ tablet can be taken with or without food. Do not take this medication with grape fruit and its juices.Ā
Q5.
Which population is contraindicated from taking SpnibĀ 50mgĀ tablet?
SpnibĀ 50mgĀ tablet is contraindicated for pregnant and breastfeeding women and children whose ages are below one year. It is not recommended if you are allergic to Dasatinib and its ingredients.
Fact Box of Spnib 50mg Tablet
| Molecule Name | Dasatinib |
| Therapeutic class |
Antineoplastics |
| Pharmacological class |
Tyrosine kinase inhibitor |
| Indications |
1. Myeloid leukemiaĀ 2. Philadelphia chromosome-positive acute lymphoblastic leukemiaĀ |
References
- Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
- Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidsonās Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
- Edward Chu, Cancer Chemotherapy, Langeās Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Disclaimer
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Author Details

Written By
Dr. Bhairavi S
Pharm. D

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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