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Spnib 20mg Tablet
Last updated on 11 Aug 2026 | 06:15 AM (IST)
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Introduction to Spnib 20mg Tablet
Spnib 20mg tablet consists of the active ingredient Dasatinib. It is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia. This medicine is used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in the chronic phase and Ph+ acute lymphoblastic leukemia in patients resistant to other therapies. Chronic Myeloid Leukemia refers to a type of blood cancer that makes the body produce too many white blood cells that happen due to alteration in the Philadelphia chromosome. Acute Lymphoblastic Leukemia is the most common form of blood cancer that affects children. In this case, the lymphocytes of white blood cells multiply too quickly and live too long.
The common side effects that are likely to associate with Spnib 20mg tablet are diarrhea, headache, cough, rash, nausea, tiredness, vomiting, muscle pain, weakness, low appetite, high or low blood pressure. Inform your doctor if these side effects disturb or persist for longer period.
Inform your doctor if you are allergic to Spnib 20mg and its ingredients. Before starting treatment with this medication, you should let your physician know if you have liver or heart problems, breathing difficulties, chest pain, cough, hepatitis B infection, bleeding problems. This medicine could cause a severe reduction in the number of platelets, WBC or RBC in the blood. Ensure that your physician monitors your blood levels at regular intervals. Tell your healthcare professional about all the medicines you take, including prescription and over-the-counter medicines, vitamins, antacids, and herbal supplements. It is not recommended for children below one year of age.
Uses of Spnib 20mg Tablet
Spnib 20mg tablet is indicated for the following conditions:
- Children and adults with chronic myeloid leukemia.
- Adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) with resistance to prior therapy.
Therapeutic Effects of Spnib 20mg Tablet
Spnib 20mg tablet works by preventing the abnormal protein from signaling the growth of cancer cells. This aids in preventing or reducing the spread of cancer cells.
Interaction of Spnib 20mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Spnib 20mg tablet and can cause undesirable side effects.
More Information about Spnib 20mg Tablet
Store protected from light at a temperature not exceeding 30c.
How to consume Spnib 20mg Tablet
Take the tablet with or without food at the same time each day. Do not break, crush or chew the tablet. Your doctor will decide the dose and frequency of administration of Spnib 20mg tablet based on your disease severity and other factors. Do not stop taking the tablet without consulting your healthcare professional.
Safety Advice for Spnib 20mg Tablet
Breast Feeding
It is not recommended to breastfeed while taking Spnib 20mg tablet as it is not known whether this medication passes into breast milk. You should not breastfeed during treatment and for 2 weeks after your final dose.
Alcohol
It is not known whether it is safe to consume alcohol with Spnib 20mg tablet. Consult your doctor for advice.
Liver
Inform your physician before starting this treatment if you have liver diseases. Your physician will prescribe a dose accordingly.
Lungs
It is unknown whether Spnib 20mg is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment.
Driving
Avoid driving or using machinery if you experience symptoms like breathlessness or altered consciousness.
Pregnancy
Spnib 20mg tablet is not recommended to use during pregnancy unless clearly necessary. Your physician will discuss the potential risk during pregnancy. Women should use effective birth control during treatment and 30 days after the final dose.
Side Effects of Spnib 20mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Unusual bleeding or bruising
- Rapid heart rate
- Changes in consciousness or speech
- Breathlessness and swelling all over the body
- Fever or signs of infection
- Fluid retention
- Heart problems
- Myelosuppression
- Severe allergic reaction
Common
- Diarrhea
- Headache
- Cough
- Rash
- Nausea, tiredness, vomiting
- Muscle pain, weakness
- Low appetite
- High or low BP
Word of Advice
It is advised to use effective contraceptives for both men and women taking Spnib 20mg tablet during treatment and 30 days after the last dose. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice blood in your urine or stools. If you are taking an antacid medicine, take it 2 hours before or 2 hours after taking this tablet.
FAQs about Spnib 20mg Tablet
Q1.
Can children use Spnib 20mg tablet?
Spnib 20mg tablet is not recommended for children under the age of one.
Q2.
Can Spnib 20mg tablet cause hair loss?
Yes, hair loss is one of the common side effects of taking Spnib 20mg. Consult your doctor for advice if this side effects disturbs or persists you.
Q3.
Is Spnib 20mg tablet a chemotherapy drug?
Yes, Spnib 20mg tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitor.
Q4.
Spnib 20mg tablet be taken with food?
Yes, Spnib 20mg tablet can be taken with or without food. Do not take this medication with grapefruit and its juices.
Q5.
Who is contraindicated to take Spnib 20mg tablet?
Spnib 20mg tablet is contraindicated for pregnant and breastfeeding women and children whose ages below one year. It is not recommended if you are allergic to Dasatinib and its ingredients.
Fact Box of Spnib 20mg Tablet
| Molecule Name: Dasatinib | Therapeutic class: Anti-neoplastics |
| Pharmacological class: Tyrosine kinase inhibitor | Indications: 1. Myeloid leukemia 2. Philadelphia chromosome-positive acute lymphoblastic leukemia |
References
- Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
- Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 11 Aug 2026 | 06:15 AM (IST)
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