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Staphar 500mg Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction
Staphar 500mg Injection contains an active component such as Flucloxacillin. It is a type of antibiotic medication that belongs to the class of drugs known as penicillins. It is used to treat various bacterial infections caused by certain bacterial strains, primarily those sensitive to its antimicrobial effects. It is commonly prescribed to treat infections caused by Staphylococcus bacteria, including Staphylococcus aureus. This medication is often used to treat skin and soft tissue infections, including boils, abscesses, cellulitis, and wound infections. Cellulitis is a bacterial skin infection characterised by redness, swelling, and pain. This medication can also treat certain respiratory tract infections caused by susceptible bacteria.it is important to use it under the guidance and prescription of a qualified healthcare provider.
Individuals with a history of hypersensitivity or severe allergic reactions (such as anaphylaxis) to penicillins or other beta-lactam antibiotics should not take Staphar 500mg Injection. You should avoid taking this medication if you have a history of jaundice (yellowing of the skin and eyes) associated with penicillin or other beta-lactam antibiotics. It should be avoided in individuals with infectious mononucleosis (mono or glandular fever), as it may lead to a rash. It should be used cautiously in individuals with certain medical conditions, such as kidney impairment or a history of gastrointestinal disease. It can be safe for children when prescribed by a healthcare provider. Elderly individuals can take Staphar 500mg Injection, but their kidney and liver function may impact the dosing.
Uses
Staphar 500mg Injection is used in the following:
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Skin and soft tissue infections
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Bone and joint infections
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Respiratory tract infections
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Endocarditis prophylaxis
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Staphylococcal infections.
How Staphar 500mg Injection works
Staphar 500mg Injection exerts its therapeutic effect through inhibition of bacterial cell wall synthesis. As a beta-lactam antibiotic, it interferes with the activity of enzymes known as penicillin-binding proteins (PBPs) that are crucial for cross-linking bacterial cell wall components. Disrupting this process weakens the integrity of the bacterial cell wall, leading to osmotic instability and, ultimately, bacterial cell death. This mechanism primarily targets bacteria like Staphylococcus aureus, rendering them susceptible to the drug's action.
Interaction of Staphar 500mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Staphar 500mg Injection, reducing its effectiveness by causing undesirable side effects.
Storage conditions
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Store at room temperature, between 20°C -25°C
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Keep away from moisture, heat, and light.
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It should not be frozen.
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Keep away from children and pets.
How to take Staphar 500mg Injection
Staphar 500mg Injection is swallowed orally with a whole glass of water. The frequency depends on age, weight, and severity of the condition, and is decided by a healthcare provider.
Safety Advices
Pregnancy
Discuss with your healthcare provider before starting Staphar 500mg Injection if you are pregnant or planning to become pregnant.
Breast Feeding
It is recommended to consult a healthcare provider before using the medication while breastfeeding.
Lungs
Staphar 500mg Injection can be prescribed for certain respiratory infections caused by susceptible bacteria. However, the choice of antibiotic depends on the specific infection and its causative organism. Always follow the healthcare provider's recommendations for treating lung infections.
Liver
Staphar 500mg Injection is metabolised by the liver, so individuals with severe liver disease should consult a healthcare provider before starting this medication.
Alcohol
Alcohol consumption might increase the risk of side effects like dizziness and lightheadedness. It is unsafe to take alcohol while using Staphar 500mg Injection.
Driving
Staphar 500mg Injection can cause dizziness or other side effects, so it's not safe to drive while on this medication.
Side Effects
Staphar 500mg Injection causes some side effects like all medications, although not everyone will experience them.
Serious
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Severe allergic reactions
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Severe skin reactions
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Liver dysfunction
Common
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Gastrointestinal disturbances
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Skin rash
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Yeast infections
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Digestive upset
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Pain or inflammation at the injection site (IV formulation).
Expert Tips
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Inform your healthcare provider about any allergies, especially to penicillin antibiotics, and any previous adverse reactions to antibiotics before starting Staphar 500mg Injection.
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Patients with liver conditions or renal impairment need close monitoring, as the drug is metabolised in the liver and excreted through the kidneys.
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Complete the full prescribed course to prevent antibiotic resistance.
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Inform your doctor if you have underlying medical conditions, are pregnant, breastfeeding, or taking other medications.
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Be cautious of potential drug interactions and report any severe side effects, such as serious skin reactions or allergic responses, immediately.
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Consult your healthcare provider if you experience unusual symptoms during treatment.
- Follow storage instructions carefully and keep the medication away from children and pets.
FAQs
Q1.
Can Staphar 500mg Injection cause photosensitivity?
Staphar 500mg Injection itself isn't a known cause of photosensitivity (increased sensitivity to sunlight). However, certain skin reactions could occur with sun exposure due to the infection or other factors.
Q2.
What should I do if I miss a dose of Staphar 500mg Injection?
If you miss a dose, take it as soon as you remember. If it's close to the time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Q3.
Can Staphar 500mg Injection interfere with birth control pills?
Staphar 500mg Injection can potentially reduce the effectiveness of birth control pills. If you're taking oral contraceptives, consider using an additional form of contraception while on Staphar 500mg Injection and consult your healthcare provider.
Q4.
Can I stop taking Staphar 500mg Injection if my symptoms improve?
No, it is important to complete the full course of Staphar 500mg Injection as prescribed, even if your symptoms improve before the medication is finished. Stopping early can lead to incomplete treatment and antibiotic resistance.
Q5.
When will I start noticing the effects of Staphar 500mg Injection?
The time it takes for Staphar 500mg Injection to work can vary based on the type and severity of the infection. Some symptom improvement may be noticed within a few days, but it's important to complete the full course as prescribe.
Fact Box
|
Molecule name |
Flucloxacillin |
|
Therapeutic class |
Antibacterial Agents |
|
Pharmacological class |
Beta-lactam antibiotic |
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Indications |
1. Skin and soft tissue infections 2. Bone and joint infections 3. Respiratory tract infections 4. Endocarditis prophylaxis 5. Staphylococcal infections |
References
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Mastroviti S, Cassarino G. La Flucloxacillin,. G Bacteriol Virol Immunol.[Published on July 1975] [Accessed on 29th Aug 2023],https://pubmed.ncbi.nlm.nih.gov/1234594/
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Aurobindo Pharma - Milpharm Ltd., Electronic Medicines Compendium (EMC), [Revised on 29th August 2023] [Accessed on 29th Aug 2023], https://www.medicines.org.uk/emc/product/545/smpc#gref
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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