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Tacrotor 0.1% Ointment 10gm
Last updated on 07 Jul 2026 | 06:03 AM (IST)
₹647
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MRP: ₹761.35
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Introduction
Tacrotor 0.1% Ointment 10 gm contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medicines to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ.
Do not take this capsule if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine.
Limit exposure to sunlight and UV light while consuming tacrolimus by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhoea; inform your physician if you have diarrhoea for over a day. If you need to receive any vaccinations, consult your doctor once before accepting them.
Uses
Tacrotor 0.1 ointment uses:
- Prevent organ transplant rejections.
How Tacrotor 0.1% Ointment 10gm Works
Tacrotor 0.1 Ointment 10gm provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.
Interaction of Tacrotor 0.1% Ointment 10gm with other drugs
Inform your healthcare provider about all the medicines that you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of tacrolimus and reduce its effectiveness by causing undesirable side effects. Avoid grapefruit or grapefruit juice while taking this medicine.
Storage Conditions
- Store Tacrotor 0.1% Ointment 10gm at (25°C)
- keep the capsule away from the reach of children and pets.
- If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose.
- Do not take a double dose to compensate for a missed dose.
- Tacrotor 0.1 ointiment price based on the seller and location.
How to Use Tacrotor 0.1% Ointment 10gm
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Tacrotor Ointment 0.1% 10gm as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take these capsules on an empty stomach or at least 1 hour before or 2 to 3 hours after the meal.
Safety Advice for Tacrotor 0.1% Ointmen 10gm
Breast Feeding
Avoid using Tacrotor 0.1% Ointment while breastfeeding, as it may pass into breast milk and harm the baby.
Alcohol
Do not consume alcohol with Tacrotor 0.1% Ointment, as it may increase the risk of drowsiness or liver damage.
Liver
Use with caution in severe liver conditions; inform your doctor before starting treatment.
Lungs
Safety in lung disease is unclear; consult your doctor if you have any respiratory issues.
Driving
Avoid driving or using machines, as Tacrotor 0.1% Ointment may cause dizziness or blurred vision.
Pregnancy
Tacrotor may affect the baby; inform your doctor if you are pregnant or planning pregnancy.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Swelling in the arm or leg
- Hair loss
- Itchy skin
- Constipation, diarrhoea
- Nausea, vomiting
- Anemia
- Headache
- Cough
Serious
- Increased or decreased heartbeats
- GI bleeding
- Liver Injury
- Seizure
- Acute kidney failure
- Lung infection or respiratory problems
Word of Advice
Do not eat grapefruit or drink grapefruit juice while Tacrotor ointment use. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.
FAQs about Tacrotor 0.1% Ointmen 10gm
Q1.
Can I use Tacrotor ointment while breastfeeding?
It has low absorption, but consult your doctor infant monitoring may be advised
Q2.
Is Tacrotor ointment safe for people with liver problems?
Use cautiously in severe liver disease; your doctor might adjust the dose or recommend alternatives
Q3.
Can Tacrotor cause drowsiness or impair driving?
While uncommon, some users may feel dizziness or blurred vision avoid driving until you know how it affects you.
Q4.
Can people with lung disease use Tacrotor ointment?
There’s no clear data on its safety with lung conditions check with your doctor before starting treatment.
Q5.
Is drinking alcohol allowed when using Tacrotor ointment?
It’s best to avoid alcohol, especially if you have liver concerns or experience sedation during treatment.
Fact Box
|
Molecule name: | Tacrolimus |
|
Therapeutic class: | Immunosuppressant |
|
Pharmacological class: | Calcineurin inhibitors |
| Indications: |
Prevent organ transplant rejections |
References
- Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022. Accessed May 25, 2023. https://www.medicines.org.uk/emc/product/6720/smpc
- Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).; Revised 2012. Accessed May 25, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1008.
- KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 881.
Disclaimer
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 07 Jul 2026 | 06:03 AM (IST)
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