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Both men and women taking Temo GBM 20mg Capsule should use effective birth control.
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Women of reproductive potential must use contraception during treatment and for six months after therapy.
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Male patients should avoid fathering children and use reliable contraception during treatment and for three months after completion.
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Routine blood tests may be recommended to monitor electrolyte levels, blood cell count, and liver function.
Quick Summary
Temo GBM 20mg Capsule
Written By:Dr. Bhairavi SPharm. D Reviewed By:Dr. Tejashwin AdigaMBBS
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹610
MRP: ₹1845
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Introduction
Temo GBM 20mg Capsule contains the active ingredient temozolomide and belongs to the class of medicines known as antitumor agents. It is primarily prescribed for the treatment of brain cancers such as glioblastoma multiforme in adults and malignant gliomas, including glioblastoma multiforme or anaplastic astrocytoma, in patients over three years of age. These are aggressive brain tumors with generally poor survival outcomes. Temo GBM vs GBMT capsule comparisons are often made by patients to understand differences in formulation, dosage, and cost.
For Temo GBM dosage instructions, anaplastic astrocytoma is treated with Temo GBM 20mg Capsule or radiotherapy after biopsy, while glioblastoma multiforme is treated with a combination of radiotherapy and Temo GBM 20mg Capsule, followed by maintenance therapy.
Regarding how to take Temo GBM capsule, it should be taken exactly as prescribed by your doctor, usually once daily on an empty stomach, with a full glass of water, without opening or crushing the capsule.
Temo GBM safety warnings include informing your doctor if you are allergic to temozolomide or any of its components, or if you have a history of hepatitis B, anemia, low platelet count, reduced RBC or WBC levels, blood clotting disorders, or liver/kidney disease. Regular monitoring of white blood cell and platelet counts will be necessary during treatment.
Temo GBM pregnancy risk is significant—this medicine should not be taken during pregnancy or while breastfeeding. Women should use effective contraception during treatment and for six months after, while men should avoid fathering a child during treatment and for at least three months afterward.
Common side effects of Temo GBM capsule include nausea, vomiting, diarrhea, constipation, dizziness, hair loss, rash, tiredness, frequent urination, vision or hearing issues, high blood sugar, muscle or joint pain, memory loss, coordination problems, infections, sleep disturbances, and weight loss. Report any persistent or severe side effects to your physician promptly.
The Temo GBM capsule price can vary depending on location, brand availability, and pharmacy, but it is widely accessible in cancer treatment centers and oncology pharmacies.
Uses
- Treatment of newly diagnosed glioblastoma multiforme.
- Treatment of refractory anaplastic astrocytoma
How Temo GBM 20mg Capsule works
Temo GBM 20mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.
Interaction of Temo GBM 20mg Capsule with other drugs
Inform your doctor about any medicines you take or have taken before the treatment.
Storage conditions
- Keep Temo GBM 20mg Capsule out of sight and reach of children.
- Store protected from light and moisture.Do not store above 25°C.
How to take Temo GBM 20mg Capsule
Use Temo GBM 20mg Capsule as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.
Safety Advice for Temo GBM 20mg Capsule
Breast Feeding
Unsafe
Temo GBM 20mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Alcohol
Consult Your Doctor
Avoid consuming alcohol while taking Temo GBM 20mg Capsule as it may cause unpleasant side effects. Consult our doctor for advice.
Liver
Consult Your Doctor
Inform your physician before taking Temo GBM 20mg Capsule if you have severe liver problems. Dose adjustment is required based on the condition.
Lungs
Consult Your Doctor
Inform your physician before taking Temo GBM 20mg Capsule if you have if you have any lung conditions.
Driving
Unsafe
Do not drive or operate heavy machines while using Temo GBM 20mg Capsule as it may decrease alertness, affect your vision and make you dizzy and sleepy.
Pregnancy
Unsafe
Temo GBM 20mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Temo GBM side effects include
Serious:
- Secondary cancer like myelodysplastic syndrome and myeloid leukemia.
- Severe Allergic reactions
- Inflammation and fluid buildup in lungs
- Blood clot in lungs or legs
- Liver toxicity
- Convulsions
- Fever and chills
- Severe headache
- Uncontrolled bleeding
Common:
- Hair loss
- Rashes
- Tiredness
- Nausea, vomiting and diarrhea
- Constipation
- High blood sugar levels
- Dizziness, impaired sensation, tingling sensation, abnormal taste
- Vision and Hearing problem
- Frequent urination
- Muscle damage, pain in muscles and joints
- Weight changes
- Infections and wounds
- Amnesia
- Abnormal blood cell counts
- Loss of appetite
- Sleep problems
- Memory loss
- Difficulty concentrating, changes in mental status and alertness
- Coordination problems
Expert Tips
FAQs about Temo GBM 20mg Capsule
Q1.
What class of medication is Temo GBM 20mg Capsule?
Temo GBM 20mg Capsule belongs to the class of medications called Antitumor agents
Q2.
Can children use Temo GBM 20mg Capsule?
No, Temo GBM 20mg Capsule is not recommended for usage in children under 3. There is limited information on patients over the age of 3 who have taken this medication. Consult your doctor before taking Temo GBM 20mg Capsule.
Q3.
What is the best time to take Temo GBM 20mg Capsule?
It is best to take Temo GBM 20mg Capsule once a day on an empty stomach. Take the capsule at the same time every day for better results.
Q4.
Can I take vaccinations while taking Temo GBM 20mg Capsule?
No, The live vaccine may interact with Temo GBM 20mg Capsule. Hence, without consulting your healthcare provider, this medication should not be taken with any vaccinations.
Q5.
Can I drive while taking Temo GBM 20mg Capsule?
Do not drive or operate heavy machines while being treated with Temo GBM 20mg Capsule as it may decrease alertness, affect your vision and make you dizzy and sleepy.
Fact Box of Temo GBM 20mg Capsule
|
Molecule name | Temozolomide |
|
Therapeutic class |
Alkylating agents |
|
Pharmacological class |
Antitumor agents |
|
Indications |
1. Treatment of newly diagnosed glioblastoma multiforme. 2. Treatment of refractory anaplastic astrocytoma |
References
1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf
2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf
3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779
4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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