Temother Neo 100mg Capsule contains the active ingredient temozolomide. It belongs to the class of medications known as Antitumor agents. It is prescribed to treat brain cancer, such as glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are the most common and aggressive brain cancers with low chances of survival. Anaplastic astrocytoma is treated with Temother Neo 100mg Capsule or radiotherapy after biopsy, whereas Glioblastoma multiforme is treated with a combination of radiotherapy and Temother Neo 100mg Capsule, and it is continued as maintenance therapy.

The common side effects that are likely to associate with Temother Neo 100mg Capsule are nausea, vomiting, dizziness, diarrhea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, high blood sugar levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep problems and loss of weight. Inform your doctor if any of these symptoms disturb you or persist.

Inform your physician if you are allergic to Temother Neo 100mg Capsule and its ingredients. Before starting treatment with this medication, let your physician know if you have hepatitis B infection, anemia, low platelet count, low level of RBC and WBC, blood clotting problems, or any liver or kidney problems. Your physician will monitor your WBC and platelet counts regularly. Avoid taking this medication if you are pregnant or breastfeeding. Both women and men should use birth control to avoid pregnancy and fathering a child.

•  Treatment of newly diagnosed glioblastoma multiforme.

• Treatment of refractory anaplastic astrocytoma

Temother Neo 100mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Temother Neo 100mg Capsule and cause undesirable side effects.

• Keep Temother Neo 100mg Capsule out of sight and reach of children.

• Store protected from light and moisture.

• Do not store above 25°C.

Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Secondary cancer like myelodysplastic syndrome and myeloid leukemia.

• Severe Allergic reactions

• Inflammation and fluid buildup in lungs

• Blood clot in lungs or legs

• Liver toxicity

• Convulsions

• Fever and chills

• Severe headache

• Uncontrolled bleeding

Common:

• Hair loss

• Rashes

• Tiredness

• Nausea, vomiting and diarrhea

• Constipation

• High blood sugar levels

• Dizziness, impaired sensation, tingling sensation, abnormal taste

• Vision and Hearing problem

• Frequent urination

• Muscle damage, pain in muscles and joints

• Weight changes

• Infections and wounds

• Both men and women taking Temother Neo 100mg Capsule should use effective birth control to prevent pregnancy.

• Women of reproductive potential must use reliable contraception during treatment and for at least six months after the last dose.

• Men undergoing Temother Neo 100mg Capsule therapy should avoid fathering children and use effective contraception during treatment and for three months after completing therapy.

• Regular blood tests may be recommended to monitor your blood cell counts, electrolyte levels, and liver function during treatment.

• Always consult your doctor before planning a pregnancy during or shortly after treatment, as Temother Neo 100mg Capsule can cause harm to the unborn baby.