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Tilpazan 284mg Injection 1.5 ml
Last updated on 15 Jul 2026 | 06:59 AM (IST)
₹85715
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1 PREFILLED SYRINGE(s) OF 1.5ML
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Introduction to Tilpazan 284mg Injection 1.5 ml
Tilpazan 284mg Injection 1.5 ml is a medicine containing Inclisiran as an active ingredient which belongs to the class of medications called proprotein convertase subtilisin kexin type-9 [PCSK-9]. It is first in class and only small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol. It is used to lower the level of low density lipoprotein. It is prescribed as a complement to statin medication and diet in the management of patients with primary high cholesterol levels.
It is not recommended to use this medication if you are allergic to the active compound Tilpazan Injection or its components. It is not recommended to use during pregnancy and breastfeeding; it is advised to consult your physician regarding further queries. It is not recommended for children and adolescents under the age of 18. You should be taking a statin and following a diet to reduce your cholesterol before beginning this therapy. For the duration that you are receiving Tilpazan 284mg Injection 1.5 ml, you should continue taking the statin and adhering to this cholesterol-lowering diet. Do not stop taking this medicine without consulting your doctor. Talk to your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, or intolerance to sugars before taking this medicine. Inform your physician or pharmacist of any additional medications you are taking, have recently taken, or may take, including over-the-counter medications and herbal remedies.
Uses of Tilpazan 284mg Injection 1.5 ml
- Combination to other statin therapy and diet for treating primary hyperlipidemia [heterozygous familial hypercholesterolemia]
Therapeutic Effects of Tilpazan 284mg Injection 1.5 ml
Tilpazan 284mg Injection 1.5 ml is a small interfering RNA (siRNA) molecule that interferes with the production of PCSK9 protein in the liver. By inhibiting PCSK9 synthesis, Tilpazan 284mg Injection 1.5 ml increases the number of LDL receptors on liver cells, promoting the clearance of LDL cholesterol from the blood. This mechanism ultimately leads to lower LDL cholesterol levels in the bloodstream, helping to reduce the risk of cardiovascular events such as heart attack and stroke.
Interaction of Tilpazan 284mg Injection 1.5 ml with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tilpazan 284mg Injection 1.5 ml and reduce effectiveness by causing undesirable side effects.
More Information about Tilpazan 284mg Injection 1.5 ml
- Tilpazan 284mg Injection 1.5 ml should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Tilpazan 284mg Injection 1.5 ml
Tilpazan 284mg Injection 1.5 ml will be administered to you by a healthcare professional in a hospital setting. It is usually administered as a subcutaneous injection into the abdomen, upper arm, or thigh. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors. The second dose is given after 3 months and the subsequent dose every 6 months.
Safety Advice for Tilpazan 284mg Injection 1.5 ml
Breast Feeding
It is unknown whether Tilpazan 284mg Injection 1.5 ml is excreted in human milk. It is advised to consult your doctor before taking Tilpazan 284mg Injection 1.5 ml. Your doctor may prescribe this if the benefits of the drug outweighs the risks involved.
Alcohol
It is unknown if consuming alcoholic beverages while taking Tilpazan 284mg Injection 1.5 ml injection is safe. Please consult with your physician.
Liver
Tilpazan 284mg Injection 1.5 ml is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases.
Lungs
It is unknown whether Tilpazan 284mg Injection 1.5 ml Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.
Driving
It is safe to travel, drive a car, or operate heavy machinery after receiving Tilpazan 284mg Injection 1.5 ml. The drug does not impair alertness or coordination
Pregnancy
It is recommended to avoid this medication during pregnancy as Tilpazan 284mg Injection 1.5 ml is unsafe during pregnancy as it can cause fetal harm. It is advised to inform your physician if you are pregnant or think you may be pregnant before starting the treatment.
Side Effects of Tilpazan 284mg Injection 1.5 ml
Like all medications, Tilpazan 284mg Injection 1.5 ml can cause side effects, although not everyone who takes it will experience them.
Common:
- Injection site reactions like redness, rash and pain
- Arthralgia
- Bronchitis
- Fever
- Chills
- Headache
Word of Advice
It is advised to adopt heart-healthy lifestyle practices, such as eating a balanced diet low in saturated and trans fats, exercising frequently, keeping a healthy weight, and quitting smoking, in addition to taking Tilpazan 284mg Injection 1.5 ml. It is advised not to stop your regular statin medications and follow proper diet since Tilpazan 284mg Injection 1.5 ml is only effective along with these two therapies. It is not recommended to discontinue the drug without the advice of a healthcare professional even if your symptoms improve. Follow your doctor's advice and routinely check your cholesterol levels. This facilitates monitoring Tilpazan 284mg Injection 1.5 ml's efficacy and enables prompt modification of your treatment regimen, if necessary. If a dose is missed for more than three months, a new dosing regimen needs to be initiated.
FAQs about Tilpazan 284mg Injection 1.5 ml
Q1.
Can Tilpazan 284mg Injection 1.5 ml be used during pregnancy or breastfeeding?
The safety of Tilpazan 284mg Injection 1.5 ml during pregnancy and breastfeeding has not been established. It is important to consult with a healthcare provider before using Tilpazan 284mg Injection 1.5 ml if you are pregnant, planning to become pregnant, or breastfeeding.
Q2.
How often do I need to have my cholesterol levels checked while taking Tilpazan 284mg Injection 1.5 ml?
Your healthcare provider will determine how often you need to have your cholesterol levels checked based on your individual health status and treatment response. Regular monitoring of cholesterol levels is typically recommended during Tilpazan 284mg Injection 1.5 ml therapy.
Q3.
Can I stop taking my other cholesterol-lowering medications if I start Tilpazan 284mg Injection 1.5 ml?
It is important to follow your healthcare provider's instructions regarding the use of other cholesterol-lowering medications while taking Tilpazan 284mg Injection 1.5 ml. Tilpazan 284mg Injection 1.5 ml may be used in addition to other medications to achieve optimal cholesterol control.
Q4.
What should I do if I miss a dose of Tilpazan 284mg Injection 1.5 ml?
If you miss a dose of Tilpazan 284mg Injection 1.5 ml, contact your healthcare provider to reschedule the missed dose. Usually Tilpazan 284mg Injection 1.5 ml is given at an interval of 3 months. It is important to maintain the prescribed dosing schedule to ensure the effectiveness of Tilpazan 284mg Injection 1.5 ml therapy in lowering LDL cholesterol levels.
Q5.
What are the common side effects of Tilpazan 284mg Injection 1.5 ml?
Common side effects of Tilpazan 284mg Injection 1.5 ml may include injection site reactions (such as pain, redness, or swelling), flu-like symptoms (such as fever, chills, or body aches), and headache. These side effects are usually mild and temporary.
Fact Box of Tilpazan 284mg Injection 1.5 ml
Molecule name: Inclisiran
| Therapeutic class: Antihyperlipidemic drugs |
| Pharmacological class: Proprotein convertase subtilisin kexin type-9 [PCSK-9] | Indications: 1. Combination to other statin therapy and diet for treating primary hyperlipidemia [heterozygous familial hypercholesterolemia] |
| Dosage form: Injection | Habit forming: No
|
References
- Novartis Pharmaceuticals Corporation , US Food and Drug Administration, [ Revised on July 2023] [ Accessed on 05-03-2024 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/214012s009lbl.pdf
- Novartis Pharmaceuticals UK Ltd. Electronic medicines compendium (emc), [ Revised on November 2022] [ Accessed on 05-03-2024], https://www.medicines.org.uk/emc/files/pil.12039.pdf
- Leqvio, Novartis Pharmaceuticals Ltd, https://www.leqvio.com/
Disclaimer
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 15 Jul 2026 | 06:59 AM (IST)
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