• Treatment of chronic lung infections caused by Pseudomonas aeruginosa, especially in cystic fibrosis

• Management of bronchiectasis with bacterial involvement

• Can be used as part of nebuliser therapy for respiratory condition

Tobamist contains tobramycin, an aminoglycoside antibiotic. When inhaled via neb Tobamist or a nebuliser, the medication directly reaches the lungs where it disrupts bacterial protein production, killing the bacteria responsible for the infection. This helps improve lung function and reduces symptoms like coughing and breathlessness over time.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with tobamist respules and can cause undesirable side effects.

• Store Tobamist Respules in a cool, dry place below 25°C.
• Keep the respules in their original foil pouch until use to protect them from light.
• Do not freeze.
• Keep out of reach of children and pets.

Use Tobamist Respules 5ml in a nebuliser as directed by your doctor. Pour the entire content into the nebuliser chamber and inhale the mist slowly through a mouthpiece or mask. Use it at the same time daily, and clean the nebuliser after each use. Do not mix with other solutions unless advised.

Like any medication, Tobamist may cause some side effects. Most are mild and temporary, but it's good to be aware:

• Hoarseness or voice changes

• Cough or sore throat

• Unusual taste in the mouth

• Breathing difficulties (rare)

• Ringing in the ears or hearing issues (especially with long-term use)

Always inform your doctor if you notice any unusual or persistent symptoms. These Tobamist side effects may not occur in everyone.

• Use Tobamist Respules exactly as prescribed by your doctor.

• Use a clean and well-maintained nebuliser for every dose.

• Don’t mix it with other nebuliser solutions unless instructed.

• Complete the full course even if you feel better early.

• If you miss a dose, take it as soon as you remember unless it's almost time for the next one.

• While Tobamist Respules are commonly used via nebulisation, Tobamist injection may be used in hospital settings for more severe infections. The form of tobramycin you receive will depend on your condition and medical recommendation.

1. Vianex SA., Electronic Medicines Compendium (EMC), [Revised on May 2022] [Accessed on 20th Oct  2023], Tobramycin 40mg/ml Injection - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
2. Fresenius Kabi USA, Inc., US Food and Drug Administration, [Revised on April 2021], [Accessed on 20th Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/050789s012lbl.pdf
3. KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 795-799