This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The U.S. FDA approved tobramycin in 1975, to treat bacterial infection (respiratory tract, urinary tract, nervous system, digestive system) and blood poisoning.
Mechanism of Action of undefined
Tobramycin acts by inhibiting the synthesis of protein in bacterial cells. It transports the aminoglycoside through the bacterial cell wall and cytoplasmic membrane and binding to ribosomes resulting in inhibition of protein synthesis.
Uses of undefined
Tobramycin treats bacterial infections (respiratory tract, urinary tract, nervous system, digestive system, and blood poisoning. It is effective only against bacterial infection and not against viral or fungal infection.
undefined Drug administaration and Dosage available
Tobramycin is available respules purposely for inhalation use in nebulizer which cannot be consumed orally. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Warnings, Precautions and Side Effects of undefined
Warnings
Inform your doctor if you are allergic to tobramycin or any of the ingredients present in them or have kidney or muscle disorder. Inform your doctor about your prescribed and non-prescribed medicine and take a proper diet while under medication. It will be helpful for him to treat you based on your previous medical or make some dose adjustments.
Precautions
Elderly patients with kidney disorders should be cautious while taking the medicine. Consult your doctor if you are planning to get pregnant or think you may be pregnant while breastfeeding. Tobramycin tablets are contraindicated to pregnant women and harmful to the unborn female baby.
Side Effects
The common side effects that are experienced while you are on the treatment with tobramycin are kidney problem, ear damage (inner ear damage), muscle problem, diarrhoea.
Word Of Advice
Your doctor will advise you to monitor serum level (Serum calcium, magnesium, and sodium) in patients with known renal impairment. Inform your doctor immediately if you feel an allergic reaction. Elderly patients with kidney disorders and individuals who are pregnant should inform your doctor before taking the medicine. Don’t take the tobamist respules orally, it is purposely for inhalation use in nebulizer. The solution should not be injected or swallowed. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Frequently Asked Question
References
- Vianex SA., Electronic Medicines Compendium (EMC), [Revised on May 2022] [Accessed on 20th Oct 2023], Tobramycin 40mg/ml Injection - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
- Fresenius Kabi USA, Inc., US Food and Drug Administration, [Revised on April 2021], [Accessed on 20th Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/050789s012lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 795-799.
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
