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Tocira 400mg Injection
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹32340
MRP: ₹40425
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Tocira 400mg Injection
Salt Composition
TOCILIZUMABMarketer
HETERO HEALTHCARE LTD
Prepaid Only. Non-Returnable.
20% OFF
₹32340
MRP: ₹40,425.00
Inclusive of all taxes
20% Off
Salt Composition
TOCILIZUMABMarketer
HETERO HEALTHCARE LTD
Prepaid Only. Non-Returnable.
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Substitutes
Actemra 400mg Injection
CIPLA LTD
₹ 34000.00/injection
6% costlier
Introduction to Tocira 400mg Injection
Tocira 400mg injection contains an active component called tocilizumab. This medicine belongs to a group of monoclonal antibody (a protein made from specific immune cells). This is used in conditions such as moderate to severe active rheumatoid arthritis (RA) and who have inadequate response with other rheumatoid drugs, giant cell arteritis (disease in arteries), children with systemic juvenile idiopathic arthritis (sJIA), polyarticular juvenile idiopathic arthritis (pJIA) which result in the pain and swelling in one or more joints in children of 1 to 2 year and above.
Children with allergic reactions to ingredients and severe infections should consult their doctor before taking the medicine. Talk to your doctor immediately if you have any allergic reaction (difficulty with breathing, chest tightness rash, itching, hives, swelling lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches developed in the digestive tract), liver disease, cancer, kidney function problems, and persistent headaches.
Inform your doctor if the Children have a history of macrophage activation syndrome (activation and uncontrolled proliferation of specific blood cells). The elderly are more likely to develop infections than the general population, so it is important to be cautious when treating them. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Uses of Tocira 400mg Injection
- Rheumatoid arthritis
- Giant cell arteritis (GCA)
- Polyarticular Juvenile Idiopathic Arthritis (pJIA)
- Systemic Juvenile Idiopathic Arthritis (sJIA)
- Cytokine release syndrome
Therapeutic Effects of Tocira 400mg Injection
Tocira 400mg injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body's inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.
Interaction of Tocira 400mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with tocira 400mg injection and can cause undesirable side effects.
More Information about Tocira 400mg Injection
- Protect from light and moisture
- Store at 2°C - 8°C
- Keep children away from the sight and reach of this medication.
How to consume Tocira 400mg Injection
Tocira 400mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advice for Tocira 400mg Injection
Breast Feeding
It is unknown whether tocira 400mg injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Alcohol
It is unknown whether tocira 400mg injection is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Liver
Inform your physician about any underlying liver disorders before taking tocira 400mg injection, as this medication should be used cautiously in liver disease patients.
Lungs
It is unknown whether tocira 400mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Tocira 400mg injection may cause drowsiness in the patient while under medication. So, it is recommended to consult your doctor before handling vehicles and machinery.
Pregnancy
Consult your healthcare provider if you plan to get pregnant. However, tocira 400mg injection has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.
Side Effects of Tocira 400mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face)
- Fever and chills
- Mouth or skin blisters
- Stomach ache
Common
- Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache)
- High blood fat (cholesterol) levels
- Injection site reactions.
- Lung infection (pneumonia)
- Shingles (herpes zoster)
- Cold sores (oral herpes simplex), blisters
- Eye infection (conjunctivitis)
- Headache, dizziness, high blood pressure
- Mouth ulceration, stomach pain
- Fluid retention (edema) in the lower legs, weight increase
- Cough, shortness of breath
- Low white blood cell counts (neutropenia, leucopenia)
- Abnormal liver function tests (increased transaminases)
- Increased bilirubin shown by blood tests
- Low fibrinogen levels in the blood (a protein involved in blood clotting)
Word of Advice
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking tocira 400mg injection. Your doctor will advise you to check the blood if you have low white blood cells, platelets, or elevated liver enzymes before giving you the medicine.
FAQs about Tocira 400mg Injection
Q1.
What precautions should I take while on tocira 400mg injection?
Be aware of any potential infections that could come up, and consult your doctor. Your doctor will advise you to check the blood test to check. Let them know if you're having any new or worse symptoms immediately.
Q2.
Can I drive when I take tocira 400mg injection?
It is recommended to avoid driving when you take the medicine, as it can cause drowsiness. Consult your doctor before driving.
Q3.
Can an elderly individual safely take tocira 400mg injection?
The elderly are more likely to develop infections than the general population, so it is important to be cautious and consult your doctor before taking the medicine.
Q4.
Can I take a vaccination while under tocira 400mg injection?
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking tocilizumab medicine.
Q5.
What is the purpose of tocira 400mg injectionin children?
It is used to treat children with systemic juvenile idiopathic arthritis (sJIA) and polyarticular juvenile idiopathic arthritis (pJIA), which result in the pain and swelling in one or more joints in children of 1 to 2 years and above.
Fact Box of Tocira 400mg Injection
Molecule name: Tocilizumab | Therapeutic class: Anti-inflammatory agents, Monoclonal antibodies |
Pharmacological class: Interleukin-6 (IL-6) receptor inhibitors | Indications: 1. Rheumatoid arthritis 2. Giant cell arteritis 3. Polyarticular Juvenile Idiopathic Arthritis 4. Systemic Juvenile Idiopathic Arthritis 5. Cytokine release syndrome |
References
- Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 26th Sep 2023], https://www.medicines.org.uk/emc/files/pil.13280.pdf
- Genentech, Inc., US Food and Drug Administration, [Revised on Aug 2017] [Accessed on 26rd Sep 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125276s114lbl.pdf
- Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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