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Tromadex 500mg Injection
Prescription Required
Salt Composition : Sugammadex
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Tromadex 500mg Injection
The Tromadex 500mg Injection contains an active component called the Sugammadex. It is used to reverse the effects of neuromuscular-blocking agents, such as rocuronium and vecuronium, which are commonly used during surgery to induce muscle relaxation. This medication helps to restore muscle function after surgery quickly and allows patients to resume normal breathing and other motor functions. In certain medical procedures, muscle relaxation is necessary for facilitating intubation or other medical interventions. It can be used to reverse the effects of muscle relaxants once the procedure is completed, helping patients recover normal muscle function more rapidly.
Individuals who have a known hypersensitivity or allergy to Tromadex 500mg Injection or any of its components should not receive this medication, as it can lead to severe allergic reactions, including anaphylaxis. Patients with severe renal impairment may require dosage adjustments or careful monitoring when receiving this medication, as the drug is primarily excreted through the kidneys.
It is important to assess the overall health status of elderly patients before administering Tromadex 500mg Injection, as they may have a higher chance of having comorbidities or reduced organ function that could impact the safety and dosage of the medication. The safety and efficacy of this medication in pediatric populations may vary.
Uses of Tromadex 500mg Injection
Tromadex 500mg Injection is used in the following:
- Anesthesia reversal
- Surgical muscle relaxation reversal
- Medical intervention reversal
Therapeutic Effects of Tromadex 500mg Injection
Tromadex 500mg Injection works by forming a complex with steroidal neuromuscular blocking agents, such as rocuronium and vecuronium, through its modified γ-cyclodextrin structure. This encapsulation sequesters the neuromuscular blocking agents, preventing them from binding to nicotinic cholinergic receptors at the neuromuscular junction. As a result, the free concentration of the neuromuscular blocking agents in the plasma is reduced, allowing the muscle fibres to be released from the blockade and restoring neuromuscular function rapidly and effectively.
Interaction of Tromadex 500mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Tromadex 500mg Injection, which reduces effectiveness by causing undesirable side effects.
More Information about Tromadex 500mg Injection
- Store Tromadex 500mg Injection at room temperature, between 20°C to 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Tromadex 500mg Injection
Tromadex 500mg Injection can be administered intravenously. The dosage and administration of this medication will be determined by a healthcare provider based on the specific needs of the patient and the medical procedure being performed.
Safety Advices for Tromadex 500mg Injection
Pregnancy
The use of Tromadex 500mg Injection during pregnancy should be carefully considered, and a healthcare professional should evaluate the potential risks and benefits.
Breast Feeding
It is important to consult with a healthcare provider before taking Tromadex 500mg Injection as it has not been studied extensively in breastfeeding women.
Lungs
Consult your healthcare provider if you have a history of lung conditions before using the Tromadex 500mg Injection.
Liver
If you have liver disorders, informing your healthcare provider before starting the Tromadex 500mg Injection is important.
Alcohol
It is not safe alcohol while taking Tromadex 500mg Injection, as alcohol can exacerbate certain side effects.
Driving
Tromadex 500mg Injection may cause dizziness or other adverse effects that could impair their ability to drive or operate machinery. If you experience these symptoms, consult your healthcare provider.
Side Effects of Tromadex 500mg Injection
Tromadex 500mg Injection causes some side effects like all medications, although not everyone will experience them.
Serious side effects of Tromadex 500mg Injection are:
- Severe allergic reactions
Common side effects of Tromadex 500mg Injection are:
- Nausea
- Vomiting
- Headache
- Shivering
Word of Advice
Check for any history of allergic reactions to Tromadex 500mg Injection or its components. Monitor patients with kidney or liver issues closely, as dosage adjustments may be necessary. Evaluate the risks and benefits of administering Tromadex 500mg Injection during pregnancy or breastfeeding. Be cautious when combining it with other medications, as interactions may occur. Monitor elderly patients closely for potential side effects. Monitor patients with respiratory or cardiovascular conditions closely during administration. Watch for signs of allergic reactions in patients with a history of such responses to other substances. Consider the impact of Tromadex 500mg Injection on patients with pre-existing neuromuscular, bleeding, or electrolyte disorders. Keep an eye on patients' vital signs, including blood pressure, heart rate, and respiratory rate, to promptly identify any adverse reactions or complications that may arise while using this medication.
FAQs
Q 1. What should I do if I miss a dose of Tromadex 500mg Injection?
Since healthcare professionals administer Tromadex 500mg Injection, the timing and dosage are carefully monitored, and a missed dose is unlikely.
Q 2. Can Tromadex 500mg Injection be used in all types of surgical procedures?
Tromadex 500mg Injection can be used in various surgical procedures that require the reversal of muscle relaxants, but its specific use will depend on the patient's needs and the healthcare provider's judgment.
Q 3. Is there a risk of developing tolerance or dependence on Tromadex 500mg Injection with prolonged use?
There is no evidence to suggest the development of tolerance or dependence with the appropriate use of Tromadex 500mg Injection as directed by a healthcare professional.
Q 4. Are there any dietary restrictions to consider while using Tromadex 500mg Injection?
There are no specific dietary restrictions associated with Tromadex 500mg Injection use. However, maintaining a healthy and balanced diet is generally recommended for overall well-being.
Q 5. How long does the effect of Tromadex 500mg Injection last?
The duration of action of Tromadex 500mg Injection varies depending on various factors, including the patient's health status and the specific muscle relaxants being reversed. Healthcare professionals will monitor the patient's recovery and response closely.
Q 6. Are there any serious allergic reactions associated with Tromadex 500mg Injection?
While serious allergic reactions are rare, they can occur, including anaphylaxis, which requires immediate medical attention.
Fact Box of Tromadex 500mg Injection
Molecule name: Sugammadex | Therapeutic class: Neuromuscular blocking agents reversal agent |
Pharmacological class: Selective relaxant binding agent | Indications: 1. Anesthesia reversal 2. Surgical muscle relaxation reversal 3. Medical intervention reversal |
References
- Merck Sharp & Dohme, Electronic Medicines Compendium (EMC), [Revised on 03 Aug 2023] [Accessed on 27th Oct 2023], https://www.medicines.org.uk/emc/product/14949/pil#gref
- Merck Sharp & Dohme Corp., U.S. Food and Drug Administration, [Revised on December 2015], [Accessed on 27th Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022225lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Drugs Acting on Peripheral (Somatic) Nervous System, 7th edition, 2013, 355
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