Ulicrit 1,00,000IU Injection is used to treat the following:

• Acute pancreatitis
• Sepsis
• Acute respiratory distress syndrome

Ulicrit 1,00,000IU Injection's mechanism of action involves inhibiting various proteolytic enzymes, such as trypsin and elastase, which are crucial in promoting inflammation and tissue damage. By suppressing these enzymes, this medication reduces the activation of inflammatory pathways and modulates the immune response, ultimately leading to decreased inflammation and potential mitigation of tissue injury.

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Ulicrit 1,00,000IU Injection, reducing effectiveness by causing undesirable side effects.

• Store at temperature 2°C - 8°C
• Keep away from moisture, heat, and light.
• It should not be frozen.
• Keep away from children and pets.

Ulicrit 1,00,000IU Injection is administered intravenously (vein injection) under medical supervision. Your healthcare professional will determine the specific dosage and administration guidelines based on your condition and needs.

Ulicrit 1,00,000IU Injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

• Severe allergic reactions (difficulty breathing, swelling of the face or throat, hives, itching)
• Anaphylaxis (a life-threatening allergic reaction)
• Signs of an infection (fever, persistent sore throat)
• Changes in kidney function (changes in urine output, swelling of the legs or ankles)
• Abnormal bleeding or bruising
• Liver problems (yellowing of the skin or eyes, dark urine, abdominal pain)
• Neurological symptoms (confusion, seizures, difficulty speaking or moving)

Common:

• Nausea
• Vomiting
• Diarrhea
• Skin rashes or itching
• Headache
• Dizziness
• Fever or chills
• Injection site reactions (pain, redness, or swelling)

Patients with known hypersensitivity to Ulicrit 1,00,000IU Injection or any of its components should not use the medication. Regular monitoring of kidney and liver function is essential, and dose adjustments may be necessary for patients with impaired organ function. Caution is advised in pregnant and breastfeeding individuals, and the medication should only be used if needed and under medical supervision. Close monitoring for signs of allergic reactions, infections, and changes in blood counts is recommended. Patients with a history of gastrointestinal or bleeding disorders should be closely monitored during treatment. It's important to discuss all medical conditions and medications with the healthcare provider to ensure the safe and effective use of these medications.

1. Bharat Serums and Vaccines Limited, [Accessed on 27th July 2023], https://www.bharatserums.com/assets/pdf/products/Upxiga(Liquid).pdf
2. Qiancheng Xu et al; Ulinastatin is effective in reducing mortality for critically ill patients with sepsis: a causal mediation analysis; Scientific Reports; [Published on 25/09/2018]; [Accessed on 27/07/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6156583/
3. Ling-Zhang wang et al; Effect of Ulinastatin on serum inflammatory factors in Asian patients with acute pancreatitis before and after treatment: a meta-analysis; International Journal of Clinical Pharmacology and Therapeutics; [Published on Nov 2016]; [Accessed on 27/07/2023]; https://pubmed.ncbi.nlm.nih.gov/27569736/