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Zebical 50mg Tablet
Prescription Required
Salt Composition : Bicalutamide
Manufacturer : ZEE LABORATORIES LTD
Origin of Medicine : India
30 Tablet(s) In A Box
Introduction to Zebical 50mg Tablet
Zebical 50mg Tablet consists of the active ingredient Bicalutamide. It is used for the treatment of advanced prostate cancer. It belongs to the category of drugs called non-steroidal anti-androgens. It is prescribed along with Luteinizing Hormone-Releasing Hormone (LHRH) analog or surgical removal of testicles.
Zebical 50mg Tablet should be taken with or without food but should be taken at a fixed time every day. Dosage of the medication will depend on the condition of the patient. This medication should be taken as prescribed by the doctor. Do not overdose this medication as it causes serious side effects and this medicine has to be taken even when the patient is feeling well.
It is a part of androgen deprivation therapy, a combination of radiation, surgical and hormonal therapy in high-risk patients. Androgen deprivation therapy lowers the levels of testosterone considerably. Prostate cancer is sensitive to androgen and hence, this treatment aims to counteract the source and effect of androgen. Report to your physician right away if you experience side effects such as blood in urine or severe allergic reactions due to this treatment.
Uses of Zebical 50mg Tablet
- Treatment of advanced prostate cancer
Therapeutic Effects of Zebical 50mg Tablet
Zebical 50mg Tablet binds to the cytosol androgen receptors and blocks the effect of the androgen hormone. It interrupts the interaction of androgen receptors to hormones testosterone and dihydrotestosterone. This, in turn, blocks the growth of cancer cells in the prostate gland.
Interaction of Zebical 50mg Tablet with other drugs
Inform your doctor about any medications you are taking or have taken before the treatment.
More Information about Zebical 50mg Tablet
Store at a temperature not exceeding 30˚C. Keep out of reach of children.
How to consume Zebical 50mg Tablet
Consume the tablet at the same time each day, with or without food.
Safety Advices for Zebical 50mg Tablet
Pregnancy
Breast Feeding
Lungs
Liver
This medicine could cause hepatic injury. Inform your physician before starting this treatment if you have liver diseases. Your physician will monitor your liver functions regularly.
Alcohol
Driving
Avoid driving or using machinery if you experience side effects like drowsiness or dizziness.
Side Effects of Zebical 50mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Severe allergic reactions such as rashes, swelling, wheezing, etc
- Depression
- Heart problems
- Changes in liver enzymes
- Blood in urine
Common:
- Body Pain
- Constipation
- Infection
- Nausea
- Peripheral edema
- Breathlessness
- Enlargement of breasts
- Anaemia
- Dizziness
- Weakness, swelling and breast tenderness
- Weight gain
- Indigestion
- Hair loss
- Low appetite
- Low sex drive
- Blood glucose problem
Word of Advice
This medication should be taken as prescribed by the doctor. This medication has to be taken with or without food but it should be taken at a fixed time daily. Inform the doctor about any allergic reactions, kidney, liver, diabetes, blood pressure and other medications taken for different medical conditions before starting this medication. Avoid driving and handling heavy machineries after taking this medication as it causes dizziness and individuals can lack consciousness and alertness. Blood count, blood pressure, liver, kidneys, blood glucose levels should be monitored regularly while using this medication.
FAQs
Q 1. Does a Zebical 50mg Tablet cause anaemia?
Yes, the common side effects of this medication is anaemia and decreased blood count levels and monitor the blood counts while taking this medication.
Q 2. Can I stop taking the Zebical 50mg Tablet if I am feeling well?
This medication should not be stopped without the proper advice of the doctor as it will worsen the condition.
Q 3. Can a Zebical 50mg Tablet cause infertility?
Yes, this medicine can interfere with the fertility in men. Consult the doctor before taking this medication.
Fact Box of Zebical 50mg Tablet
Molecule name | Bicalutamide |
Therapeutic class | Trifluoromethyl Benzene Derivative |
Pharmacological class | Antineoplastics |
Indications | Prostate cancer |
References
- AstraZeneca Pharmaceuticals, U.S. Food & Drug Administration, [Revised on Oct 2017] [Accessed on 15th Jun 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020498s028lbl.pdf
- AstraZeneca, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 6th Dec 2021], https://www.medicines.org.uk/emc/files/pil.5491.pdf
- Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.
Disclaimer
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