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Zoladex LA 10.8mg Injection
Salt Composition : Goserelin Acetate
Manufacturer : ASTRAZENECA PHARMA INDIA LTD
Origin of Medicine : United Kingdom
1 Prefilled Syringe(s)
Introduction to Zoladex La 10.8mg Injection
Zoladex LA 10.8mg injection is a chemotherapy agent containing the active constituent Goserelin Acetate. This medicine belongs to the luteinizing hormone-releasing hormone (LHRH) agonists. In Men, it is used in combination with other medicines to treat localized prostate cancer and used alone to treat advanced prostate cancer. In women, it is used to treat advanced breast cancer, endometriosis, and uterine fibroids. It is also used as an endometrial-thinning agent before surgery on your uterus. It also helps to treat infertility with other medicines. Inform your doctor immediately if you face any injection site injury after receiving the injection.
Zoladex LA 10.8mg injection works by reducing testosterone hormone in men and estrogen hormone in women. Do not use this medicine if you are pregnant or breastfeeding. Inform your doctor if you have high blood pressure or heart problems, including rhythm changes. Consult your doctor if you face any mood changes like depression or anxiety when taking this medicine. This medicine is not indicated in children. The most common side effects of Zoladex LA 10.8mg injection in men are hot flashes, urinary tract infections, and sexual dysfunction. In women, hot flashes, acne, sweating, and depression are the common adverse effects of this medicine.
Uses of Zoladex La 10.8mg Injection
- In men, used in combination with other drugs to treat Prostate cancer
- In women, used to treat advanced breast cancer
- Used to treat endometriosis (A disorder in which tissue that normally lines the uterus grows outside the uterus) and uterine fibroids.
- Used as an endometrial-thinning agent before performing any surgery in your uterus.
- Used to treat infertility in women with other medicines.
Therapeutic Effects of Zoladex La 10.8mg Injection
Zoladex LA 10.8mg injection belongs to luteinizing hormone-releasing hormone (LHRH) agonists. It works by inhibiting certain hormones, which may stimulate the growth of cancer cells. In males, it reduces testosterone levels; in females, it reduces estrogen levels.
Interaction of Zoladex La 10.8mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Zoladex LA 10.8mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Zoladex La 10.8mg Injection
- Store Zoladex LA 10.8mg injection in the original package at room temperature ( Do not exceed 25°C)
- Keep away from children and pets
- If you miss an appointment to receive the injection, discuss it with your healthcare professional and reschedule the appointment.
How to consume Zoladex La 10.8mg Injection
This medicine is administered to you by your doctor or healthcare professional in a clinic or hospital. Do not self-administer. Usually, Zoladex LA 10.8mg injection will be injected under the skin (subcutaneously) in your stomach area every four weeks. Your doctor will decide the dose and duration of your medicine. Always remind your next appointment for your next injection. The length of your treatment depends on the condition's severity and your response to the medication.
Safety Advices for Zoladex La 10.8mg Injection
Zoladex LA 10.8mg injection should not be used during pregnancy. It can cause fetal harm. Inform your physician if you are pregnant or planning to get pregnant. It is necessary to consult a physician before starting the treatment.
Zoladex LA 10.8mg injection should not be used during breastfeeding. It may excrete in breast milk and cause harm to the unborn baby. Inform your physician if you are breastfeeding and get advice.
It is unknown whether Zoladex LA 10.8mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
It is safe to administer Zoladex LA 10.8mg injection in patients with liver disorders. There is no dose adjustment required. Consult your physician for more advice.
It is not known whether it is safe to consume alcohol with Zoladex LA 10.8mg injection. Please consult your doctor.
Taking Zoladex LA 10.8mg injection does not usually affect your ability to drive. Please consult the doctor for more advice.
Side Effects of Zoladex La 10.8mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Hot flushes and Sweating
- Swelling in the hands and legs
- Depression and mood swings
- Erectile dysfunction
- Sexual dysfunction
- Pain, bruising, and bleeding
- Pain while urinating ( in men)
- Dryness or itching of the vagina
- Thinning of bones
- Increased blood pressure
- Increased risk of Heart failure
- Increased risk of Diabetes
- Increased risk of stroke
- Injection site injury
- Severe skin reactions
Word of Advice
Inform your physician if you have any heart, diabetes, kidney, liver or lung disorders before the treatment. If you are male and have difficulty urinating, inform your doctor immediately. Do not take Zoladex LA 10.8mg injection if you are allergic to goserelin or other ingredients in it. Your duration of receiving this medicine depends on why you are using this medicine. Birth control pills should not be used while taking this medicine; you may require secondary birth control methods such as condoms, the diaphragm, or the cervical cap. Consult your physician for more advice on pregnancy, breastfeeding, and birth control methods.
Q 1. How is Zoladex LA 10.8mg injection typically given (administered)
Zoladex LA 10.8mg injection will be given to you by your healthcare professional. It is given under the skin (subcutaneously) in your stomach area every 4 weeks. Your doctor will decide the dose and duration of the therapy based on your condition and how well you respond to the treatment.
Q 2. What are the common side effects of Zoladex LA 10.8mg injection in women?
In women, hot flashes, depression, acne, dryness or itching of the vagina, and excessive sweating are the common side effects of Zoladex LA 10.8mg injection.
Q 3. Can Zoladex LA 10.8mg injection cause hair loss?
Mild hair loss is possible with the treatment. If you face more hair fall, consult your doctor for advice.
Q 4. Is Zoladex LA 10.8mg injection used to treat infertility in women?
Yes, Zoladex LA 10.8mg injection is used in combination with other drugs to treat infertility in women.
Q 5. Can Pregnant women take Zoladex LA 10.8mg injection?
No, Zoladex LA 10.8mg injection should not be given to pregnant women. It can cause harm to the unborn baby.
Fact Box of Zoladex La 10.8mg Injection
Molecule name: Goserelin Acetate
Therapeutic class: luteinizing hormone-releasing hormone (LHRH) agonists
Pharmacological class: Anti-Neoplastic drug
1. Prostate cancer in men
2. Breast cancer in women
4. Uterine fibroids
5. Female infertility
- Package leaflet: Information for the user Zoladex 3.6 mg Implant goserelin. (2015). [online] Available at: https://www.medicines.org.uk/emc/files/pil.1543.pdf [Accessed 24 Jan. 2023].
- HIGHLIGHTS OF PRESCRIBING INFORMATION. (2015). [online] Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019726s050s051s052lbl.pdf [Accessed 24 Jan. 2023].
- HIGHLIGHTS OF PRESCRIBING INFORMATION. (2015b). [online] Available at: https://documents.tersera.com/zoladex-us/3.6mg_MagnumPI.pdf [Accessed 24 Jan. 2023].
- Tripathi, K.D. (2019). Essentials of medical pharmacology. New Delhi: Jaypee Brothers Medical Publishers, pp.263–264 [Accessed 24 Jan. 2023].
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