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Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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ACETAMINOPHEN,CODEINE PHOSPHATE
Last updated on 31 Mar 2026 | 09:31 AM (IST)
ACETAMINOPHEN,CODEINE PHOSPHATE
Background and Date of approval ACETAMINOPHEN,CODEINE PHOSPHATE
Acetaminophen + Codeine phosphate belongs to the therapeutic class of pain analgesics.
Uses of ACETAMINOPHEN,CODEINE PHOSPHATE
Acetaminophen + Codeine phosphate is used to treat various conditions, such as muscle aches, back pain, joint pain, menstrual cramps, and toothache.
How is ACETAMINOPHEN,CODEINE PHOSPHATE administered?
Acetaminophen + Codeine phosphate is primarily administered orally. The dose and duration will depend on what you take it for and how well it helps your symptoms.
Side Effects of ACETAMINOPHEN,CODEINE PHOSPHATE
Serious side effects of Acetaminophen + Codeine phosphate include breathing trouble, chest pain, fast heartbeat, swelling, agitation, high body temperature, trouble walking, stiff muscles, and mental changes such as confusion. Common side effects of this medication are nausea, vomiting, constipation, dizziness, and sleepiness.
Warnings
In malnourishment cases, the medicine is poorly absorbed, accumulating unused medicine in your blood. This medication may cause severe gastrointestinal (stomach and intestines) bleeding and perforation (holes) after prolonged usage.
Precautions
Acetaminophen + Codeine phosphate should be used with extreme caution if you have malnourishment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Word of Advice
Acetaminophen + Codeine phosphate with or without food. Drink plenty of water to avoid stomach irritation. Do not break, crush, or chew the tablets. Do not take in larger doses than prescribed by your doctor. Avoid consuming alcohol with this medicine, as it can worsen your dizziness. Keep this medicine away from children and pets. If your condition does not improve in one week or is associated with fever, rash, or breathing difficulty, consult your doctor. Avoid consumption of foods containing caffeine and/or drinks such as tea, chocolate, and coffee since it leads to excessive dizziness and sleepiness.
Frequently Asked Questions
Q1.
Is Acetaminophen + Codeine phosphate a habit-forming medicine?
No habit-forming tendencies were reported for Acetaminophen + Codeine phosphate.
Q2.
How long does it take for Acetaminophen + Codeine phosphate to take effect?
Acetaminophen + Codeine phosphate relieves pain and cramps within 1 hour.
Q3.
What are the most common side effects of receiving Acetaminophen + Codeine phosphate?
The most common side effects of Acetaminophen + Codeine phosphate is dizziness, excess sleepiness, stomach upset, nausea, abdominal discomfort, diarrhea, and/or peripheral edema (swelling in legs/arms). Consult your doctor if any of the symptoms worsen.
Q4.
How long do the effects of Acetaminophen + Codeine phosphate last?
The duration of action of Acetaminophen + Codeine phosphate is about 6 hours.
Q5.
What if you forget to take Acetaminophen + Codeine phosphate?
If you miss a dose of Acetaminophen + Codeine phosphate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double the dose.
References
- Par Pharmaceutical, Inc., [Revised on Sep 2019] [Accessed on 8th Nov 2023], https://dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=a8ff3132-fd89-49ff-8623-971f01289df7
- Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.
- Mark A. Schumacher, Allan I. Basbaum, Ramana K. Naidu, Opioid Agonists & Antagonists, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 553-574.
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.






