Gonadotropin is an antineoplastic drug that belongs to the category of medicines known as luteinizing hormone analogues. It was approved by the FDA in 1974 to treat infertility in women.

Gonadotropin is used to treat undescended testicles and hypogonadism in men. It is also used to treat infertility in women.

This injection will be administered into the muscle or under the skin. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Gonadotropin injection usually comes in vials containing a powder. The powder must be mixed with sterile water or bacteriostatic water before injection. After the injection, the healthcare provider may apply pressure to the injection site to help reduce any discomfort or swelling in the injected area.

The common side effects that are likely to occur with this injection are pain, redness, swelling at the site of injection, headache, tiredness, depression, fluid retention. Inform your healthcare provider if these side effects concern you or persist for longer than usual. This medicine may increase the risk of developing ovarian hyperstimulation syndrome. If you get lower abdominal pain, gain any weight rapidly, and have difficulty in breathing, consult with your doctor.

Gonadotropin is not recommended for pregnant women, because it may harm the developing fetus. If you have a medical history of blood clots, heart disease, liver disease, kidney disease this injection should be used with caution by your healthcare professionals. In case you're allergic to this injection, report with your doctor immediately.

It is not known whether Gonadotropin can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment. This medicine may cause drowsiness or dizziness. It is unsafe to drive vehicles or operate heavy machinery after taking this Injection because Gonadotropin contains a small amount of alcohol which may cause dizziness and impair your concentration.

Gonadotropin can cause harm to a developing fetus or nursing baby, so it is important to discuss contraception options and the need to avoid breastfeeding during treatment. This drug causes fatigue, so encourage the patient to take enough rest and self-care during treatment. Gonadotropin increases the risk of bleeding and bruising, so it is important to be careful when using sharp objects or participating in activities that may result in injury. Store this injection in the refrigerator (2°-8°C). Do not freeze. Keep it out of reach from children and pets. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

1. Merck Europe BV, Electronic medicines compendium (emc), [Revised on October 2020] [ Accessed on 16th March 2023], https://www.medicines.org.uk/emc/files/pil.5527.pdf
2. APP Pharmaceuticals, LLC, US Food and Drug Administration, [Revised on April 2011] [ Accessed on 16th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/017067s057lbl.pdf
3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1123.
4. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 241.

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.