Micronised Purified Flavonoid fractions of Rutaceae are composed of Diosmin and Hesperidin and fall under the category of Flavonoid Agents.

Micronised Purified Flavonoid Fractions of Rutaceae treat chronic venous insufficiency (CVI) and manage symptoms of varicose veins. It also helps treat venous ulcers, manage haemorrhoids, and reduce oedema. Additionally, it supports lymphedema as adjunctive therapy and aids in post-surgical care to improve recovery and reduce complications.

Healthcare providers typically administer Micronised Purified Flavonoid Fractions of Rutaceae orally in tablet form, with the dosage and frequency based on the specific condition being treated. Patients should follow their healthcare provider's instructions for the correct dosage and duration of use. They should take the tablets with water, preferably during or after a meal, to ensure optimal absorption. Always consult a healthcare professional before starting or adjusting the treatment to ensure it is suitable for your individual health needs.

Side Effects are unwanted symptoms caused by medicines. Although all medications cause side effects, not everyone gets them.

Serious side effects of Micronised Purified Flavonoid fractions of Rutaceae are: 

• Allergic reactions
• Gastric disturbances

Common side effects of Micronised Purified Flavonoid fractions of Rutaceae are: 

• Gastrointestinal discomfort
• Headache
• Dizziness

• Hypersensitivity: Individuals with known allergies or hypersensitivity to Micronised Purified Flavonoid Fractions of Rutaceae or any of its components should not use this medication.
• Not for acute conditions: This medication is not a treatment for acute deep vein thrombosis (DVT) or pulmonary embolism (PE).
• Renal impairment: Use with caution in individuals with severe renal impairment, as the medication may accumulate in the body due to impaired kidney function.
• Pediatric use: This medication is not typically recommended for children, as its safety and efficacy in pediatric populations have not been well established.
• Bleeding risk: Individuals with bleeding disorders or those taking anticoagulants should use this medication with caution and under healthcare provider supervision.

If you have a known hypersensitivity to Micronised Purified Flavonoid Fractions of Rutaceae or any of its components, avoid using this medication. If you have renal impairment or bleeding disorders or take anticoagulants, your healthcare provider may need to adjust the dosage or consider alternative treatments. 

You should only use this medication during pregnancy or breastfeeding if your healthcare provider determines that the benefits outweigh the risks. Inform your healthcare provider or surgical team about your use of this medication, especially before surgery. Be cautious when combining this medication with other dietary supplements or herbal products, as interactions may occur.

Strictly stick to the prescribed dosage and administration instructions to ensure safety and effectiveness. Schedule regular follow-up appointments with your healthcare provider, especially for long-term use, to assess treatment progress and monitor for side effects. Store the medication as per the manufacturer’s guidelines, away from children, and at the recommended temperature. 

If you experience any unusual or severe side effects, including allergic reactions, seek immediate medical attention. Always consult your healthcare provider before starting this medication, particularly if you are pregnant, breastfeeding, or have underlying health conditions.

1. Taj Pharma, [Revised on Feb 2016] [Accessed on 22nd Sept 2023]https://tajpharmaindia.com/wp-content/uploads/2016/05/Diosmin-Hesperidin-Supplement-VENOSTOR-Tablets.pdf
2. Sirlak M et al. Micronized purified flavonoid fraction in pretreating CABG patients. Tex Heart Inst J. 2010; [Accessed on 22nd Sept 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851420/
3. I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.