This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3 belong to nutritional supplements and is primarily used in the management of Polycystic Ovary Syndrome (PCOS) to improve insulin sensitivity, hormonal balance and fertility.
Mechanism of Action of undefined
Myo-inositol, D-chiro-inositol, and Berberine improve insulin sensitivity, regulate glucose metabolism, and support ovarian function. L-methylfolate promotes DNA synthesis and reproductive health, while Chromium enhances insulin action and blood sugar control. Vitamin D3 strengthens bones, boosts insulin sensitivity, and supports hormonal balance. Together, they effectively manage metabolic and reproductive health.
Uses of undefined
The combination of Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3 is used to manage PCOS, improve insulin sensitivity, regulate menstrual cycles, and support fertility. It strengthens bones through Vitamin D3, improves ovarian health, and helps with glucose metabolism and blood sugar regulation, promoting overall metabolic and reproductive well-being.
undefined Drug administaration and Dosage available
For the combination of Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3, swallow tablets or capsules whole with water—do not chew, break, or crush them. If using the sachet, mix the desired dose with 100 mL of water and drink it immediately to ensure proper absorption and effectiveness.
Warnings, Precautions and Side Effects of undefined
Warnings
- Pregnancy and breast-feeding: Consult your healthcare provider before use.
- Diabetes/Insulin Resistance: Use cautiously with other blood sugar-lowering medications due to the risk of hypoglycemia.
- Kidney issues: Use with caution, especially if you have kidney problems.
- Allergic reactions: Discontinue if you experience difficulty breathing or swelling of the face or throat.
- Vitamin D toxicity: Do not exceed the recommended dose to avoid elevated calcium levels and complications.
- Drug interactions: Consult your healthcare provider before combining with other medications, especially blood sugar-lowering, thyroid, or anticoagulant drugs.
Precautions
Before using Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3, consult a healthcare provider if pregnant, breastfeeding, or taking other medications. Monitor blood sugar if diabetic, avoid exceeding the Vitamin D3 dose to prevent toxicity, and use cautiously with kidney issues. Discontinue if allergic reactions occur and maintain hydration and a balanced diet.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.
Common side effects of Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3 are:
- Gastrointestinal discomfort (bloating, gas, diarrhoea, or constipation)
- Nausea
- Headache
- Fatigue
- Skin reactions (mild rashes or irritation)
Serious side effects of Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3 are:
- Severe gastrointestinal issues (persistent diarrhoea or abdominal pain)
- Hypoglycemia
- Allergic reactions (difficulty breathing, swelling of face or throat)
- Kidney issues
- Vitamin D toxicity (elevated calcium levels)
Word Of Advice
Use the combination of Myo-inositol, Berberine, L-methylfolate, D-chiro-inositol, Chromium, and Vitamin D3 as directed by your healthcare provider. Monitor your blood sugar levels if diabetic and avoid exceeding the recommended dose, especially of Vitamin D3, to prevent potential side effects. Always consult your doctor before starting any new supplement regimen.
Frequently Asked Question
References
1. Nordio M, Bezerra Espinola MS, Bilotta G, Capoccia E, Montanino Oliva M. Long-Lasting Therapies with High Doses of D-chiro-inositol: The Downside.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9821166/
2. Unfer V, Facchinetti F, Orrù B, Giordani B, Nestler J. Myo-inositol effects in women with PCOS: a meta-analysis of randomised controlled trials.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5655679/
3. Ye Y, Liu X, Wu N, Han Y, Wang J, Yu Y, Chen Q. Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. https://pmc.ncbi.nlm.nih.gov/articles/PMC8107691/
4. Stracquadanio M, Ciotta L, Palumbo MA. Effects of myo-inositol, gymnemic acid, and L-methylfolate in polycystic ovary syndrome patients.
https://pubmed.ncbi.nlm.nih.gov/29265900/
5. Fazelian S, Rouhani MH, Bank SS, Amani R. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.
