The U.S. FDA approved Relugolix on December 18, 2020. This medicine is used to treat advanced hormone-sensitive prostate cancer.

It is used to treat adults with advanced hormone-sensitive prostate cancer.

Relugolix is available as a 120mg tablet which can be consumed orally with food. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

The common side effects that are experienced while you are on the treatment with Relugolix hot flushes, increased blood sugar levels, increased blood fat (triglyceride) levels, muscle and joint pain, decreased blood hemoglobin levels, increased liver enzymes, tiredness, constipation, diarrhea, dizziness, headache, nausea, rash, fatigue, low red cell count (anemia), breast enlargement in men (gynecomastia), sleeplessness, depression, high blood pressure, increased sweating, decreased interest in sex and increased weight.

Inform your doctor if you have a severe kidney disorder before using the medicine. Consult your doctor if you have an allergy to relugolix or sodium or any of the ingredients present in them. Speak with your doctor if you have a bone disorder or weakened bone. Because long-term use of the drug may lead to decreased bone density in males due to the suppression of testosterone, inform your doctor if you are trying to become a father or use an effective contraceptive while under medication; it may cause fertility problems in males.

Consult your doctor if you have a heart problem before using the medicine. This medicine is not intended for the use of pregnant and breastfeeding women, and it might increase the risk of pregnancy in pregnant women.

Inform your doctor if you have a liver problem or are going to take a liver function test; it can alter the results of the patients. Drink enough water and take electrolytes to compensate for the water loss during the diarrhea. It is recommended to avoid junk foods and eat fiber-rich foods to manage constipation. Taking adequate rest can help you to improve muscle, joint pain, and tiredness. Your doctor might recommend you monitor the treatment progress by PSA (prostate-specific antigen) test. Monitor your blood pressure and glucose levels during the medication.

1. Accord Healthcare Polska Sp.z o.o., European Medicines Agency (EMA), [Revised on April 2022], [ Accessed 06 Mar 2024], https://www.ema.europa.eu/en/documents/product-information/orgovyx-epar-product-information_en.pdf
2. Bushu Pharmaceuticals Ltd, Electronic medicines compendium (emc), [Revised on Dec 2020], [ Accessed 06 Mar 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/214621s000lbl.pdf

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.