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Salt Composition : Alpha Ketoanalogue
Manufacturer : STEADFAST MEDISHIELD PVT LTD
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Aplazar Tablet
Aplazar tablet is a nutrient supplement with an active ingredient called Alpha Ketoanalogue. It belongs to the class of medicine called amino acids. It is given along with a protein-restricted diet to delay the progression of chronic kidney disease (CKD). It reduces uraemic symptoms (caused by the accumulation of nitrogenous waste compounds normally eliminated by the kidneys), improves nutritional status, and reduces metabolic complications in CKD patients. It works by lowering urea levels in the bloodstream and slowing down the advancement of kidney disease, thereby delaying the need for long-term dialysis.
Do not consume Aplazar tablet if you are allergic to Alpha Ketoanalogue or any of its ingredients. Avoid consuming this medicine if you have hypercalcemia (high level of calcium) or abnormal heartbeats; because the administration of this medicine may cause increased calcium levels in the blood and irregular heartbeats. During treatment, your doctor may recommend periodic monitoring of your serum calcium levels. Notifying your doctor if you are pregnant and breastfeeding before taking this medicine.
Uses of Aplazar Tablet
- Treatment of Chronic kidney disease
- Delaying disease progression and the onset of dialysis
- Reducing metabolic complications due to renal insufficiency
- Reduction of uraemic symptoms
Therapeutic Effects of Aplazar Tablet
Aplazar tablet is classified as a nutritional supplement that operates through comparable catabolic pathways to amino acids. Enhanced protein metabolism promotes improved renal function, thereby delaying the progression of chronic kidney disease. Additionally, it ensures the intake of essential amino acids.
Interaction of Aplazar Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Aplazar tablet and can cause undesirable side effects.
More Information about Aplazar Tablet
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Aplazar Tablet
Take the Aplazar tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advices for Aplazar Tablet
Limited information is available on the use of Aplazar tablet during pregnancy. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.
Limited information is available on using Aplazar tablet during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
It is unknown whether the Aplazar tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
It is unknown whether the Aplazar tablet is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
It is unknown whether consuming alcohol while taking an Aplazar tablet is safe. Please speak with your physician.
It is not known whether it is safe to consume alcohol with Aplazar tablet. Consult your doctor for more information.
Side Effects of Aplazar Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Increased calcium level in the blood
Word of Advice
Inform your doctor if you have any other kidney disease and about all the underlying medical conditions. Do not stop the Aplazar tablet until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
Q 1. How to manage the side effects of the Aplazar tablet?
To manage the side effects of the Aplazar tablet, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor your calcium level regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Q 2. What is an Aplazar tablet?
Aplazar tablet are nutritional supplements containing essential amino acids and keto analogs. They improve protein metabolism and support renal function in patients with chronic kidney disease. They are prescribed to manage and delay the progression of kidney disease.
Q 3. Can you take Aplazar tablet when pregnant?
Consult your medical professional regarding the use of Aplazar tablet during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q 4. What are the side effects of Aplazar tablet?
A common side effect of Aplazar tablet is increased calcium levels in the blood. It is crucial to consult your doctor for any concerns or persistent side effects.
Q 5. What should I do if I miss a dose of Aplazar tablet?
If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose of the Aplazar tablet.
Fact Box of Aplazar Tablet
|Molecule Name: Alpha Ketoanalogue||Therapeutic class: Nutritional supplement|
Pharmacological class: Amino Acids
1. Treatment of Chronic kidney disease
2. Delaying disease progression and the onset of dialysis
3. Reducing metabolic complications due to renal insufficiency
4. Reduction of uraemic symptoms
- Rivpra formulation PVT LTD, [ Revised on Jan 2021] [Accessed on 15th June 2023], https://www.centaurpharma.com/downloads/2021/nephrology/NEFROGARD.pdf
- Alexander Zemchenkov, Irina N.Konakova; Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia - city nephrology registry data for outpatient clinic; BMC Nephrology; [Published on 07/07/2016]; [Accessed on 15th June 2023] https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0281-z
- Arun Sharma et al; Rationale of α-Ketoanalogue Supplemented with Low Protein Diet for the Treatment of Chronic Kidney Disease; Journal of Karnali Academy of Health Sciences; [Published on 09/01/2021]; [Accessed on 15th June 2023]; https://jkahs.org.np/jkahs/index.php/jkahs/article/view/415/222
- Che-Hsiung Wu et al; Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease; [Published on 05/05/2021]; [Accessed on 15th June 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5419544/
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