Ketotifen Fumarate:
A second-generation antihistamine that acts as both a mast cell stabiliser and a histamine receptor blocker. It prevents allergic flare-ups by reducing the release of inflammatory chemicals responsible for symptoms like sneezing, itching, and breathing difficulty.

• Prevents and controls allergic reactions, including sneezing, nasal congestion, and watery eyes.
  

• Reduces airway inflammation and helps prevent asthma symptoms, such as wheezing and coughing.
  

• Improves breathing comfort in individuals with chronic allergic conditions.
  

• Minimises dependence on bronchodilators when used as a maintenance therapy for mild asthma.
  

• Relieves skin allergies, including itching and hives caused by allergens.
  

• Promotes better sleep quality by reducing nighttime allergy-related symptoms.

• Take one Ketotime Tablet twice daily or as directed by your physician.
  

• Swallow the tablet whole with water; do not chew or crush it.
  

• It is best taken with meals to minimise stomach upset.
  

• Continue taking the medication regularly for preventive benefits; it may take a few weeks for the full effect.
  

• Do not stop the medicine suddenly without consulting your doctor.

• Store below 25°C, in a cool, dry place away from sunlight and moisture.
  

• Keep out of the sight and reach of children.
  

• Do not use the tablet after the expiry date mentioned on the pack.

• Individuals suffering from seasonal or perennial allergies.
  

• Patients with mild persistent asthma or allergy-triggered wheezing.
  

• People experiencing chronic allergic rhinitis or conjunctivitis.
  

• Not recommended for children under 3 years unless prescribed by a paediatrician.

• Avoid alcohol, sedatives, or tranquillisers while taking Ketotime Tablet, as it may increase drowsiness.
  

• Consult your doctor before use if you are pregnant or breastfeeding.
  

• Caution is advised if you have epilepsy, liver problems, or diabetes.
  

• Do not drive or operate machinery if you feel sleepy or dizzy after taking this medication.
  

• Inform your doctor about all other prescription or over-the-counter drugs you are taking to avoid interactions.
  

• Take the tablet at the same time daily for consistent results.
  

• Continue use even if symptoms improve, especially in chronic allergy or asthma prevention.
  

• Avoid exposure to known allergy triggers such as dust, smoke, and pet dander.
  

• Maintain hydration and a balanced diet to support immune function.
  

• For asthma prevention, use as part of a comprehensive treatment plan that includes inhalers or bronchodilators if prescribed.

1. Rivpra Formulation Pvt. Ltd., [ Revised on Jan 2021] [Accessed on 15th June 2023], https://www.centaurpharma.com/downloads/2021/nephrology/NEFROGARD.pdf

2. Alexander Zemchenkov, Irina N.Konakova; Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia - city nephrology registry data for outpatient clinic; BMC Nephrology; [Published on 07/07/2016]; [Accessed on 15th June 2023] https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0281-z

3. Arun Sharma et al; Rationale of α-Ketoanalogue Supplemented with Low Protein Diet for the Treatment of Chronic Kidney Disease; Journal of Karnali Academy of Health Sciences; [Published on 09/01/2021]; [Accessed on 15th June 2023]; https://jkahs.org.np/jkahs/index.php/jkahs/article/view/415/222

4. Che-Hsiung Wu et al; Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease; [Published on 05/05/2021]; [Accessed on 15th June 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5419544/