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Alfusin D 10mg Tablet
Prescription Required
Salt Composition : Alfuzosin Hcl,dutasteride
Manufacturer : CIPLA LTD
Origin of Medicine : India
15 Tablet(s) In A Strip
Introduction to Alfusin D 10mg Tablet
Alfusin D 10mg Tablet contains two active ingredients in one tablet. One of the active substances is Alfuzosin Hcl, which belongs to the group of medications called alpha-adrenoreceptor antagonists. The other active substance is Dutasteride belonging to the group of medications called 5-alpha-reductase inhibitors. This combination is used to treat symptoms associated with benign prostatic hyperplasia in men (enlarged prostate). It refers to a non-cancerous prostate gland growth, which can result in urinary problems such as difficulty in passing urine, frequent or urgent need to urinate, and urinary dribbling.
Do not take Alfusin D 10mg Tablet if you have severe liver disease or hepatic impairment. This drug is metabolized in the liver, so severe liver dysfunction can affect the clearance of these medications and potentially lead to adverse effects. This tablet should be used cautiously in individuals with moderate to severe kidney impairment. Dose adjustments may be necessary in these cases, and close monitoring of renal function is advised. If you are scheduled for cataract surgery or any other eye procedure, notify your ophthalmologist that you are taking this tablet. The medication has been associated with intraoperative floppy iris syndrome (IFIS), which can complicate the surgical procedure.
Alfusin D 10mg Tablet can cause a drop in blood pressure, leading to orthostatic hypotension (a sudden drop in blood pressure upon standing up). If a person has a history of orthostatic hypotension or is prone to low blood pressure, this drug should be used with caution. It is not recommended for adolescents and children under the age of 18. This drug is specifically indicated for use in men and should not be taken by women.
Uses of Alfusin D 10mg Tablet
- Benign prostatic hyperplasia (BPH)
Therapeutic Effects of Alfusin D 10mg Tablet
Alfuzosin is an alpha-1 adrenergic receptor blocker that works by selectively relaxing the smooth muscles in the prostate gland and the bladder neck. This helps relieve urinary symptoms caused by BPH. Dutasteride is a 5-alpha-reductase inhibitor that reduces the production of dihydrotestosterone (DHT), a hormone responsible for prostate enlargement.
Interaction of Alfusin D 10mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications interact with Alfusin D 10mg Tablet and reduce their effectiveness by causing undesirable side effects.
More Information about Alfusin D 10mg Tablet
- Store the Alfusin D 10mg Tablet at room temperature (20°C to 25°C).
- Keep it out of reach of children and pets.
How to consume Alfusin D 10mg Tablet
Your doctor will decide the dose and duration of Alfusin D 10mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time every day, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advices for Alfusin D 10mg Tablet
Pregnancy
Alfusin D 10mg Tablet is indicated only for males. If you have a pregnant female partner, suspect pregnancy, or planning for pregnancy, inform your doctor and seek medical advice.
Breast Feeding
If your partner is breastfeeding, use a reliable form of barrier contraception while using this Alfusin D 10mg Tablet. Inform your physician if you have a breastfeeding female partner.
Lungs
Whether Alfusin D 10mg Tablet can be used in patients with lung disorders is unknown. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Alfusin D 10mg Tablet should be cautiously administered in patients with liver diseases. Dose adjustments are necessary for severe liver failure. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unsafe to consume alcohol when taking Alfusin D 10mg Tablet because it may cause excessive drowsiness or liver problems.
Driving
Driving vehicles or operating machinery while taking Alfusin D 10mg Tablet is unsafe because it may cause drowsiness.
Side Effects of Alfusin D 10mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Impotence
- Decreased libido
- Ejaculation disorder
- Headache
- Nausea
- Abdominal pain
- Upper respiratory tract infection
- Breast enlargement in male
- Breast tenderness in male
Word of Advice
This medicine can lower blood pressure, which may cause dizziness or fainting, especially when changing positions (from lying down to standing up). To minimize the risk, rise slowly and gradually from a sitting or lying position. It is important to maintain good hydration while taking Alfusin D 10mg Tablet. Drink adequate water throughout the day unless otherwise advised by your healthcare provider. If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose. Do not take a double dose to compensate for a missed dose.
FAQs
Q 1. Can Alfusin D 10mg Tablet be taken at any time of the day?
Yes, Alfusin D 10mg Tablet can be taken at any time of the day. However, taking it at the same time each day is generally recommended for better medication adherence. It can be taken with or without food, as directed by your healthcare provider.
Q 2. Can Alfusin D 10mg Tablet be taken with certain supplements or herbal products?
Certain supplements or herbal products may interact with Alfusin D 10mg Tablet, affecting its effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all your supplements or herbal products before starting or modifying your medication regimen.
Q 3. What are the long-term effects of taking Alfusin D 10mg Tablet?
The long-term effects of taking Alfusin D 10mg Tablet can vary from person to person. There have been some reports of hepatotoxicity (liver damage) associated with this drug use, although this is considered rare. It is essential to monitor liver function through regular blood tests if you take alfuzosin for an extended period.
Q 4. How long does it take for Alfusin D 10mg Tablet to work?
During the initial treatment period, some individuals may experience a more rapid response, while others may require more time to see significant improvements. It is essential to continue taking Alfusin D 10mg Tablet as your healthcare provider prescribes, even if you do not see immediate results.
Q 5. Whether women can take Alfusin D 10mg Tablet?
No, Alfusin D 10mg Tablet is specifically indicated for use in men and should not be taken by women.
Q 6. Can I drive while taking Alfusin D 10mg Tablet?
Alfusin D 10mg Tablet may cause dizziness or drowsiness in some individuals, affecting your ability to drive or operate machinery safely. If you experience these side effects, avoiding activities requiring alertness is advisable.
Fact Box of Alfusin D 10mg Tablet
Molecule name: Alfuzosin Hcl + Dutasteride | Therapeutic class: Urologics |
Pharmacological class: 1. Alfuzosin Hcl- Alpha-adrenoreceptor antagonists 2. Dutasteride- 5-alpha-reductase inhibitors | Indications: Treatment of benign prostatic hyperplasia (BPH) |
References
- Sanofi, Electronic medicines compendium (EMC), [Revised on Sept 2020] [ Accessed on 13th June 2023], https://www.medicines.org.uk/emc/files/pil.1475.pdf
- Rivopharm UK Ltd, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 13th June 2023], https://www.medicines.org.uk/emc/files/pil.8988.pdf
- Ciplamed; Accessed on 13th June 2023; https://ciplamed-library.com/content/alfusin-d-tablets
- Package leaflet: Information for the user -Xatral 10mg tablets. www.hpra.ie. [Revised on Dec 2019], [ Accessed on 13th June 2023],https://www.hpra.ie/img/uploaded/swedocuments/2205503.PPA0465_138_002.856a0b73-285a-41e8-9b98-7a162579cd59.000001Xatral%20PIL.180515.pdf
- Package leaflet: Information for the user -Xatral 10mg tablets. www.hpra.ie. [Revised on Feb 2019], [ Accessed on 13th June 2023],https://www.hpra.ie/img/uploaded/swedocuments/b9581434-1b99-4640-806c-e9dd8a3531dc.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma, 7th edition, 2013, 142.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Androgens, 12th edition, 2011, 1205.
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