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Aprelieva 150mg Injection
Prescription Required
Salt Composition : Fosaprepitant Dimeglumine
Manufacturer : Allieva Pharma Pvt. Ltd.
Origin of Medicine : India
1 Vial(s)
Introduction to Aprelieva 150mg Injection
Aprelieva 150mg injection is used to treat vomiting and nausea. It is commonly administered as an injection to control the acute and delayed nausea and vomiting associated with cancer treatment, including high-dose cisplatin (highly emetogenic) and also in moderately nauseating cancer chemotherapy.
The contraceptives fail to work efficaciously during the treatment with Aprelieva 150mg injection. Concomitant administration of warfarin significantly alters the blood clotting time, so it is necessary to monitor the patients on chronic warfarin therapy before initiating Aprelieva 150mg injection. It is contraindicated in hypersensitive individuals. The dosage regimen includes the use of oral dexamethasone in the treatment.
Uses of Aprelieva 150mg Injection
- High emetogenic cancer chemotherapy
- Moderately emetogenic cancer chemotherapy
Therapeutic Effects of Aprelieva 150mg Injection
It works by acting on the receptors responsible for nausea and vomiting, antagonising the substances involved in the same.
Interaction of Aprelieva 150mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, vitamin or nutritional supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Aprelieva 150 mg injection and can cause undesirable side effects.
More Information about Aprelieva 150mg Injection
Store refrigerated at 2° to 8° C.
How to consume Aprelieva 150mg Injection
It will be administered intravenously by health care professionals. The reconstituted or diluted solutions should be checked for the presence of precipitate or cloudiness.
Safety Advices for Aprelieva 150mg Injection
Pregnancy
There are no established adverse effects of the Aprelieva 150 mg injection during pregnancy. It is advisable to take it only under specialist advice on requirements. Consult your doctor about the potential risks of this medication.
Breast Feeding
Inform your physician if you are breastfeeding before taking this medicine.
Lungs
It is unknown whether Amitant 150 mg injection is safe when administered in lung failure patients. Please consult the doctor if you have any lung problems.
Liver
Inform your physician if you have any liver disorders before starting treatment with Aprelieva 150mg injection.
Alcohol
It is unsafe to consume alcohol with an Aprelieva 150mg injection. Please consult your doctor.
Driving
The medicine may make you dizzy, so avoid driving or handling heavy machines if you are unwell.
Side Effects of Aprelieva 150mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Skin blistering, peeling
- Low white blood cell count
- Anemia
- Anaphylactic reactions
- Urinary tract infection
- Pain in extremity
- Abnormal physical weakness
- Infection
- Nerve damage
Common:
- Fatigue
- Diarrhea
- Indigestion
- Anemia
- Rash, urticaria
- Itching
Word of Advice
This injection should be administered only by the doctor or nurse, and do not self-administer this injection. Inform the doctor if the patient has any history of allergic reactions, liver or kidney problems, and other medication taken for different medical conditions. Consult the doctor if the patient is planning for pregnancy or breastfeeding mother before taking this medication. Avoid driving and handling heavy machinery as it causes dizziness. Patients may feel a lack of concentration and alertness.
FAQs
Q 1. Is Aprelieva 150mg Injection a chemotherapy medication?
It is an antiemetic medication that prevents nausea and vomiting caused by chemotherapy (cancer treatment).
Q 2. Can Aprelieva 150mg Injection be given to children?
No, this injection is not recommended for children under six months of age or who weigh less than 6kg. Consult the doctor before taking this injection.
Q 3. Can Aprelieva 150mg Injection be given for liver disorders?
This injection is used with caution in severe liver disorders, and dosage adjustment is required. Consult the doctor before taking this medication.
Q 4. Can Aprelieva 150mg Injection be used in pregnancy?
No, it is not recommended in patients during pregnancy or who are planning for pregnancy as it causes harmful effects on the developing baby.
Q 5. Can I drink while using Aprelieva 150mg Injection?
It is unsafe to use this medication while consuming alcohol because it reduces the effectiveness of the medicine.
Q 6. Can I drive after using Aprelieva 150mg Injection? No, avoid driving, as this medication can cause dizziness. Patients may lack concentration and alertness.
No, avoid driving, as this medication can cause dizziness. Patients may lack concentration and alertness.
Fact Box of Aprelieva 150mg Injection
| Molecule Name: Fosaprepitant Dimeglumine | Therapeutic Class: Antiemetic |
Pharmacological Class: Neurokinin-1 Receptor Antagonist
| Indications: To prevent nausea and vomiting due to chemotherapy. |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
- Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date Feb 2016], [Accessed date 2nd April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022023s014lbl.pdf
- National Cancer Institute, [Accessed date 2nd April 2021] +https://www.cancer.gov/publications/dictionaries/cancer-terms/def/fosaprepitant-dimeglumine
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