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Arbaz 60mg Injection
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Introduction
Arbaz 60mg Injection contains the active constituent cabazitaxel. It is an anticancer medicine used with steroid medicine prednisone or prednisolone to treat people with hormone-refractory metastatic prostate cancer that has progressed after treatment with other anticancer medications, including docetaxel. Cancer is an abnormal and uncontrolled multiplication of cells. Many early-stage prostate cancers need normal testosterone (male hormone) levels to grow. In hormone-refractory metastatic prostate cancer, cancer keeps growing even when the amount of testosterone in the body is reduced to low levels. This medicine should not be used if you have a severe abnormal liver function or recently vaccinated against yellow fever.
Its major toxicities include myelosuppression, neurotoxicity, and allergic reactions. Neutropenia is the most common adverse reaction of Arbaz 60mg Injection. Monitoring of complete blood counts is essential on a weekly basis during cycle 1 and before each treatment cycle thereafter so that the dose can be adjusted, if needed. Vaccination with a live attenuated vaccine should be avoided in patients receiving Arbaz Injection, instead killed or inactivated vaccines can be administered.
Consult your doctor before using this medication if you are pregnant or plan to have a baby. This drug is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your health care practitioner will conduct a pregnancy test before you start treatment with Arbaz 60mg Injection. Discuss with your doctor effective birth control methods and utilise them for at least two weeks following the last dose. Avoid breastfeeding your baby while on the treatment as it is unknown if this drug passes into the breast milk. Arbaz 60mg injection price in India is based on the seller and the place. You can Buy Arbaz 60mg injection online at platforms like MrMed At Affordable Prices.
Uses
Advanced prostate cancer.
How Arbaz 60mg Injection Works
It is a mitotic inhibitor that works by disrupting the normal process of cell division. This interferes with the microtubules that help to form the cell's cytoskeleton. Microtubules are essential for the normal process of cell division, as they help to pull apart the chromosomes during mitosis. By inhibiting microtubules, Arbaz 60mg Injection prevents the cancer cells from dividing properly and ultimately leads to their death.
Interaction of Arbaz 60mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Arbaz 60mg Injection and reduce effectiveness by causing undesirable side effects.
Storage Conditions
- Store Arbaz 60mg Injection in the original package at room temperature (30°C).
- Do not refrigerate.
How to Use Arbaz 60mg Injection
The medicine will be administered to you by a healthcare professional in a hospital setting. The recommended dose for this drug is 25mg, administered as an intravenous infusion over one hour every three weeks, in combination with oral prednisone (10 mg daily). The Arbaz 60mg injection dosage for Prostate cancer can be adjusted based on individual patient factors, such as age, body weight, and other medical conditions.
Safety Advice for Arbaz 60mg Injection
Breast Feeding
It is unsafe to breastfeed during the treatment with this Arbaz 60mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Alcohol
It is unknown whether consuming alcohol interacts with the Arbaz 60mg Injection. Please consult your doctor for more advice.
Liver
It is unknown whether Arbaz 60mg Injection can be used for patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.
Lungs
It is unknown whether Arbaz 60mg Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking the Arbaz 60mg Injection because it contains a small amount of alcohol which may cause dizziness and impair your concentration.
Pregnancy
It is unsafe to use during pregnancy whether Arbaz 60mg Injection can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects
The Arbaz injection side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Low white blood cells
- Infection (fever, cough, muscle aches, burning on urination)
- Severe allergic reactions (rash, itching, breathing problems, swelling of face, chest, or throat tightness)
- Kidney damage
- Severe stomach pain
Common:
- Low red blood cell count
- Low blood platelet count
- Constipation
- Back pain, joint pain
- Decreased appetite
- Hair loss
- Numbness, burning, tingling, or decreased sensation in your feet or hands
- Taste change
- Headache, dizziness
- Inflammation of mouth
- Blood in urine
Expert Tips
- Drink at least two litres of fluids every day when you are having diarrhoea. Avoid milk, dairy products, high fibre food or spicy food while you are having diarrhoea. Rinsing your mouth with an alcohol-free mouth gargle or salt water may help reduce chances of infections like mouth ulcers.
- Risk of infection can occur as this drug can reduce the WBC count in your blood, so it is advised to avoid crowds and people who are sick, wash your hands after toileting.
- You must not become pregnant during treatment and must use an effective method of contraception. If pregnancy occurs during your treatment, you must inform your doctor immediately.
- This drug may make you dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. If you are addicted to alcohol, have liver disease or epilepsy, talk to your doctor before taking this medicine.
FAQs about Arbaz 60mg Injection
Q1.
Why is prednisone given with Arbaz 60mg Injection?
This drug is designed to kill cancer cells by decreasing their ability to divide into more cells. Prednisone is taken with Arbaz 60mg Injection as part of the chemotherapy regimen to possibly slow the growth of cancer cells and reduce side effects from chemotherapy
Q2.
How does Arbaz 60mg Injection work?
This drug shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Q3.
Who should not use Arbaz 60mg Injections?
Arbaz 60mg Injection is not indicated for children and adolescents under the age of 18. It should not be used in people who are allergic to Arbaz 60mg Injection, as well as pregnant or breastfeeding women.
Q4.
Is it safe for women of reproductive potential to use Arbaz 60mg Injections?
It is not recommended for forarbaz 60mg injection uses during pregnancy and breastfeeding. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.
Q5.
What should I avoid while taking Arbaz 60mg Injections?
It is advised to avoid eating grapefruit or drinking grapefruit juice as it may increase the concentration of drugs in your blood, leading to a higher risk of side effects.
Fact Box
|
Molecule name: |
Cabazitaxel |
|
Pharmacological class: |
Mitotic inhibitors |
|
Therapeutic class: |
Anticancer |
|
Indications: |
Advanced prostate cancer |
References
Annex I summary of Product Characteristics - European Medicines Agency. Available at:https://www.ema.europa.eu/en/documents/product-information/jevtana-epar-product-information_en.pdf [ Accessed on 29th March 2023]
Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapy, 14th edition, 2017, 963.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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