Arbitus 500mg Tablet contains the active constituent abiraterone acetate. It is used in adult men to treat prostate cancer, which has spread to other parts of the body. It is usually given with steroid medication to lower the chances of side effects. When Arbitus 500mg Tablet is prescribed for an early stage of this disorder, it is used with testosterone lowering treatment. This medicine is not for use in women or children. Effective contraception must be taken throughout the treatment. This medicine contains lactose and sodium, inform your physician if you have lactose intolerance or on a salt control diet.

Inform to the physician if the patients have liver problems, high blood pressure, heart disorders, low blood potassium, diabetes, allergic conditions, or other diseases. Make sure to inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start the treatment with this medication. The most common side effects of this medication are fluid in feet or legs, high blood pressure, and diarrhea. A decrease in red blood cells and reduced sex drive may also occur with the intake of Arbitus 500mg Tablet. This medicine should not be taken with Ra-223, which is used to treat prostate cancer. 

• Treatment of prostate cancer.

Abiraterone acetate works by inhibiting the production of hormone testosterone in the body. This can slow the growth of prostate cancer.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Arbitus 500mg Tablet and cause undesirable side effects.

• This medicine does not require any particular storage condition.
• Keep out of sight and reach of children.

Arbitus 500mg Tablet medicine should always be consumed as per the direction of your physician or pharmacist. The drug should be taken by mouth. It should not be taken with food. Swallow the tablets whole with water without breaking them. Food must be eaten at least 2 hours before taking the medication and must not be eaten for at least 1 hour after taking the medicine. Women who are pregnant or who may become pregnant should not touch this medication without gloves.

Side effects are unwanted symptoms caused by medical treatment. Although all medicines can cause side effects, everyone will not get them. 

Serious:

• Low blood potassium levels (muscle weakness, muscle twitches, or pounding heartbeat)

Common

• Fluid in legs or feet
• Low blood potassium
• High blood pressure
• Urinary tract infection
• Diarrhea
• High-fat levels in the blood
• Chest pain
• Irregular heartbeat
• Rapid heart rate
• Bone fracture
• Indigestion
• Blood in urine
• Rash

Inform the doctor if the patient has any liver problems, blood pressure, heart disorders, diabetes and medication taken for different medical conditions before taking Arbitus 500mg Tablet. The medicine should be taken as prescribed by the doctor. This medication should be taken orally in an empty stomach. It should not be taken with food and swallow the tablet as a whole with water without breaking them. Food must be eaten at least 2 hours before taking the medication and the patient is advised to eat after 1hr after consuming the medication. Blood pressure, potassium levels, liver function tests should be monitored regularly while taking this medication.

1. Centocor Ortho Biotech Inc, US Food and Drug Administration, [ Revised date: APR 2011] [ Accessed date: 26 MAY 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202379lbl.pdf

2. Janssen- Cilag International NV, Electronics Medicine Compendium (emc), [Revised date: SEP 2021] [ Accessed date: 26 MAY 2022], https://www.medicines.org.uk/emc/files/pil.2381.pdf

3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Natural products in cancer chemotherapy: hormones and related agents, 12th edition, 2011, 1707 - 1709.