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Celtranz 500mg Injection
Prescription Required
Salt Composition : Tranexamic Acid
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
1 Ampoule(s)
Introduction to Celtranz 500mg Injection
Celtranz 500mg Injection contains the active compound tranexamic acid. It belongs to a group of medicines called antifibrinolytics (medications that prevent the breakdown of blood clots). It is indicated in patients with hemophilia (a disorder where blood doesn't clot normally) for short-term use to prevent blood loss. It is an effective option that is favored for preventing or managing excessive bleeding linked to fibrinolytic medications, cardiopulmonary bypass surgery, tooth, tonsil, or prostate removal, as well as heavy menstrual bleeding in females.
It is not recommended to take this medication if you are allergic to the active substance Celtranz 500mg Injection or its components. If you have a history of kidney problems, blood disorders, or seizures (fits), inform your doctor before taking this medication. You need to inform your physician if you have any liver disorders. Tell your physician about all the medications you are taking before starting treatment.
Uses of Celtranz 500mg Injection
- Prevent bleeding in hemophilia patients after tooth extraction
- Management of gastrointestinal bleeding
- Managing heavy menstrual bleeding in females.
- Management of bleeding following surgery
Therapeutic Effects of Celtranz 500mg Injection
Celtranz 500mg Injection acts by stopping the breakdown of blood clots. It does this by blocking the lysine binding site on a plasminogen protein. This prevents plasminogen from breaking down fibrin, a key component of blood clots, and helps to maintain clot stability. In simpler terms, it helps to keep blood clots intact and prevents excessive bleeding.
Interaction of Celtranz 500mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Celtranz 500mg Injection and cause undesirable side effects.
More Information about Celtranz 500mg Injection
- Do not store above 25°C.
- Do not freeze
- Keep children and pets out of reach.
How to consume Celtranz 500mg Injection
Treatment should be started under the guidance of a healthcare provider. It will be injected directly into your veins (intravenous) by your healthcare provider. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advices for Celtranz 500mg Injection
Pregnancy
Celtranz 500mg Injection is known to pass the placenta. Therefore, it is used cautiously; your physician will provide it to you only when necessary.
Breast Feeding
Celtranz 500mg Injection is excreted in breast milk. Therefore, the use of this medication during breastfeeding is not advisable. Tell your doctor if you are breastfeeding before taking this medication.
Lungs
Patients with lung diseases should consult their healthcare providers before using Celtranz 500mg Injection to ensure personalized decision-making based on their specific health conditions.
Liver
The safety of Celtranz 500mg Injection injection for individuals with liver problems is not well established. Inform your doctor of any liver disorders before receiving this injection.
Alcohol
Alcohol use can cause drowsiness and can affect normal drug absorption in the body. Hence, it is not recommended to consume alcohol during this treatment. Consult your doctor for more advice.
Driving
Patients should be informed that Celtranz 500mg Injection may produce dizziness and visual disturbances, so they should exercise caution when operating machinery, driving, or performing other risky tasks while taking it.
Side Effects of Celtranz 500mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (skin rash, lumps)
- Breathing difficulties
- swelling of the face, neck, and legs
- Weakness on one side of the body
- Blood clot formation
Common
- Nausea, vomiting, diarrhea
- Giddiness
- Low blood pressure
- Visual disturbances
Word of Advice
Patients who take this medication for an extended period may experience color vision abnormalities and other problems linked to their eyes. Thus, it is necessary for individuals receiving ongoing, long-term treatment to undergo routine ophthalmologic exams. Talking to your doctor is crucial if you have renal issues because the kidneys significantly eliminate Celtranz 500mg Injection. Dosage modifications may be necessary. Inform your physician if you have had blood in your urine, which could indicate a clot in your upper urinary tract. Blood clots are more likely to occur in women using hormonal birth control pills. Talk to your doctor about any worries you may have. Some herbal supplements may interact with this medication, particularly those with potential blood-thinning effects (e.g., ginkgo biloba, garlic, ginger). Inform your healthcare provider about the supplements you are taking.
FAQs
Q 1. Are there any side effects associated with Celtranz 500mg Injection?
Common side effects may include nausea, diarrhea, and headache. In rare cases, more severe side effects can occur, and it's important to seek medical attention if any unusual symptoms arise.
Q 2. Is Celtranz 500mg Injection available over the counter?
Celtranz 500mg Injection is available only with a prescription in many places. Consult a healthcare professional before using it.
Q 3. What to avoid when taking Celtranz 500mg Injection?
It is advised not to take hormonal contraceptive pills or any blood thinners. Consult with your physician r before starting or stopping any medication while using Celtranz 500mg Injection.
Q 4. Can individuals with kidney problems receive Celtranz 500mg Injection?
Individuals with kidney issues should inform their healthcare provider, as dosage adjustments may be necessary, given that the kidneys play a role in eliminating the medication.
Fact Box of Celtranz 500mg Injection
Molecule Name: Tranexamic acid | Therapeutic class: Hemostatic agents |
Pharmacological class: Antifibrinolytic drugs | Indications: 1. Managing heavy menstrual bleeding in females. 2. control or prevent excessive bleeding after surgical procedures |
References
- Industria Farmaceutica Galenica Senese S.r.l., Electronic medicines compendium “(EMC)” , [Revised on March 2020 ] [Accessed on December 2023]
https://www.medicines.org.uk/emc/files/pil.8835.pdf - Pfizer Injectables ,US Food and Drug Administration (FDA) [Revised on January 2021] [Accessed on December 2023]
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019281s047lbl.pdf - Pfizer Manufacturing, [Revised on June,2023] [Accessed on December 2023]
https://labeling.pfizer.com/ShowLabeling.aspx?id=15029 - KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.
- Goodman and Gilman's The Pharmacological Basis of Therapeutics, Blood Coagulation and Anticoagulant, 13th Edition, 2017,596
Disclaimer
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