• Prevent bleeding in hemophilia patients after tooth extraction
• Management of gastrointestinal bleeding
• Managing heavy menstrual bleeding in females.
• Management of bleeding following surgery

Celtranz 500mg Injection acts by stopping the breakdown of blood clots. It does this by blocking the lysine binding site on a plasminogen protein. This prevents plasminogen from breaking down fibrin, a key component of blood clots, and helps to maintain clot stability. In simpler terms, it helps to keep blood clots intact and prevents excessive bleeding.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Celtranz 500mg Injection and cause undesirable side effects. 

• Do not store above 25°C.
• Do not freeze
• Keep children and pets out of reach.

Treatment should be started under the guidance of a healthcare provider. It will be injected directly into your veins (intravenous) by your healthcare provider. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

• Severe allergic reactions (skin rash, lumps)
• Breathing difficulties
• swelling of the face, neck, and legs
• Weakness on one side of the body
• Blood clot formation

Common

• Nausea, vomiting, diarrhea
• Giddiness
• Low blood pressure
• Visual disturbances

Patients who take this medication for an extended period may experience color vision abnormalities and other problems linked to their eyes. Thus, it is necessary for individuals receiving ongoing, long-term treatment to undergo routine ophthalmologic exams. Talking to your doctor is crucial if you have renal issues because the kidneys significantly eliminate Celtranz 500mg Injection. Dosage modifications may be necessary. Inform your physician if you have had blood in your urine, which could indicate a clot in your upper urinary tract. Blood clots are more likely to occur in women using hormonal birth control pills. Talk to your doctor about any worries you may have.   Some herbal supplements may interact with this medication, particularly those with potential blood-thinning effects (e.g., ginkgo biloba, garlic, ginger). Inform your healthcare provider about the supplements you are taking.

1. Industria Farmaceutica Galenica Senese S.r.l., Electronic medicines compendium “(EMC)” , [Revised on March 2020 ] [Accessed on December 2023] 
               https://www.medicines.org.uk/emc/files/pil.8835.pdf 
2. Pfizer Injectables ,US Food and Drug Administration (FDA)  [Revised on January 2021] [Accessed on December 2023]
   https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019281s047lbl.pdf 
3. Pfizer Manufacturing, [Revised on June,2023] [Accessed on December 2023]  
             https://labeling.pfizer.com/ShowLabeling.aspx?id=15029 
4.  KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.
5.    Goodman and Gilman's The Pharmacological Basis of Therapeutics, Blood Coagulation and Anticoagulant, 13th Edition, 2017,596