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Ciclib 125mg Capsule
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹3046
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Introduction
Ciclib 125mg is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medicines known as cyclin-dependent kinase inhibitors. This medicine is primarily used in the treatment of hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. Cancer occurs when cells multiply uncontrollably and spread to other parts of the body.
Ciclib capsule for breast cancer is usually prescribed in combination with other anticancer medicines such as hormonal therapies to improve treatment effectiveness. The Ciclib 125mg dosage should be taken exactly as directed by your doctor, as it may vary depending on your condition and treatment response.
If you are looking to start treatment, you can check the Ciclib 125mg price in India or buy Ciclib 125mg online through trusted and verified pharmacies under medical supervision. It’s important to purchase only from licensed sources to ensure authenticity and safety.
The Ciclib 125mg manufacturer ensures the medicine meets quality standards, and several Ciclib 125mg substitutes in India may also be available under different brand names containing the same active ingredient, palbociclib.
Before starting this medicine, patients often consult their oncologist or pharmacist to understand Ciclib 125mg reviews, dosage schedules, and possible side effects. Always use this medicine under medical supervision and adhere strictly to your doctor’s instructions for optimal results.
Uses
Ciclib 125mg capsule uses are
- Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How Ciclib 125mg Capsule works
Ciclib 125 mg works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
Interaction of Ciclib 125mg Capsule with other drugs
Inform your doctor about all medications, including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of Ciclib 125 mg with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.
Storage conditions
- Keep Ciclib 125 mg out of sight and reach of children.
- Store at 20°C to 25°C.
How to take Ciclib 125mg Capsule
Take Ciclib 125 mg exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Safety Advice for Ciclib 125mg Capsule
Breast Feeding
It is not recommended to take Ciclib 125 mg while breastfeeding as it is not known whether it passes into the breast milk.
Alcohol
It is unknown whether it is safe to drink alcohol while taking Ciclib 125 mg capsule. Check with your doctor for advice.
Liver
Inform your physician if you have any liver disorders before taking Ciclib 125 mg, as it should be used with caution in liver disorder patients.
Lungs
It is not unknown whether Ciclib 125 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Ciclib 125 mg can cause tiredness. Avoid driving if you are unwell.
Pregnancy
It is not recommended to take Ciclib 125 mg during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Ciclib 125mg side effects are
Serious
- Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
- Lung inflammation (chest pain, dry cough, or difficulty breathing)
Common
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
Expert Tips
-
Avoid consuming grapefruit, its juices, and any products containing St. John’s wort during Ciclib 125 mg treatment.
-
Use effective birth control during treatment and for at least:
-
3 weeks after the final dose (for females)
-
14 weeks after the final dose (for males)
-
-
This medication may reduce fertility — discuss any concerns with your physician before or during treatment.
-
Your doctor may recommend regular blood tests to monitor if Ciclib 125 mg affects your blood cell count.
FAQs about Ciclib 125mg Capsule
Q1.
Is Ciclib 125 mg targeted therapy?
Yes, Ciclib 125 mg is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.
Q2.
Do you lose hair on Ciclib 125 mg?
Yes, Taking Ciclib 125 mg can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.
Q3.
Can children use Ciclib 125 mg?
No, Ciclib 125 mg is not recommended for adolescents and children under 18.
Q4.
Does Ciclib 125 mg affect fertility?
Yes, Ciclib 125 mg may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.
Q5.
Does Ciclib 125 mg affect blood cell count?
Ciclib 125 mg might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking Ciclib 125 mg are advised.
Fact Box of Ciclib 125mg Capsule
|
Molecule name | Palbociclib |
|
Therapeutic class | Anti-Neoplastics |
|
Pharmacological class | Cyclin-dependent kinase inhibitor |
|
Indications | HR-positive, HER2-negative advanced or metastatic breast cancer |
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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