CILAMIN 250MG CAPSULE

Introduction:

Cilamin 250mg Capsule consists of the active ingredient Penicillamine. It is primarily used to treat Wilson’s disease and rheumatoid arthritis. Wilson’s disease is a condition that occurs due to excess accumulation of copper in the body. It is a chelating agent that forms a complex with the heavy metals in the body, especially copper, and facilitates its excretion through urine. It is also used in the treatment of cystinuria heavy metal poisoning. 

Uses of Cilamin 250mg Capsule:

Cilamin 250mg Capsule is indicated to treat the following conditions:

• Wilson’s Disease
• Heavy metal poisoning when used with Calcium disodium EDTA and Dimercaprol.
• Excess cystine excretion in patients with cystinuria.
• Severe, active Rheumatoid Arthritis

How Cilamin 250mg Capsule Works:

Cilamin 250mg Capsule is a chelating agent that works by forming a ring-like complex with elements such as copper, mercury, zinc, lead etc., and enhances its excretion in urine. When used with Calcium disodium EDTA and Dimercaprol, the concentration of heavy metals in the blood decreases significantly. This low concentration is maintained long after the patient is discharged from the hospital. In the case of rheumatoid arthritis, Cilamin 250mg Capsule reduces the Rheumatoid factor and selectively suppresses mediators of inflammation.

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store in a controlled room temperature (20-25˚C), in a tightly sealed container.

References:

1. Michael C. Byrns and Trevor M. Penning, Environmental Toxicology: Carcinogens and Heavy Metals, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1297-1315.
2. Bausch Health US, LLC, [Revised on Oct 2020] [Accessed on 7th Apr 2021], https://www.bauschhealth.com/Portals/25/Pdf/PI/Cuprimine-PI.pdf

How to use Cilamin 250mg Capsule: 

Take Cilamin 250mg Capsule on an empty stomach. Do not take any other drug, food, milk, antacid or iron-containing food for at least an hour of taking the Capsule.

Safety Advice: 

Pregnancy:

Cilamin 250mg Capsule can cause harm to the fetus and is also associated with birth defects. Inform your physician if you are pregnant or think you might be pregnant.

Breastfeeding: 

Discuss with your physician before starting this treatment if you are breastfeeding or planning to breastfeed your baby.

Kidney:

Cilamin 250mg Capsule is not recommended for patients with kidney diseases. Inform your physician before initiating treatment, if you have kidney disease. Ensure that routine urine analysis is done at regular intervals.

Allergies:

Cilamin 250mg Capsule is associated with increased allergies. Inform your physician if you have hypersensitivity.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Nephrotic syndrome (Kidney toxicity)
• Neuropathy
• Skin reactions
• Anaemia

Common:

• Anorexia
• Nausea, vomiting, diarrhea
• Epigastric pain
• Bone marrow depression
• Protein in urine or blood in urine
• Visual and mental disturbances
• Hair loss