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Penicitin 250mg Capsule
Last updated on 11 Apr 2026 | 08:46 AM (IST)
₹142
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₹142
MRP: ₹167.16
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Introduction
Penicitin 250mg Capsule contains the active substance penicillamine. Primarily it is a chelating agent, which means it can bind to certain metals in your body, including copper and lead, to help remove them from your body. It is used to treat Wilson’s disease and lead poisoning. It also belongs to a group of medicines called DMARDS (disease-modifying antirheumatic drugs). It helps to relieve the pain and stiffness caused by rheumatoid arthritis in adults and children. It also treats still’s diseases in children.
Penicitin 250mg Capsule also treats a kidney problem called cystinuria in adults and children. It is also indicated to treat chronic active hepatitis (a type of liver disease) in adults. Do not take this medicine if you are allergic to penicillamine or any of the other ingredients of this medicine. Do not take this medicine if you have ever had a reduction in WBC after taking this medicine. Do not take this medicine if you have ever had aplastic anemia (severe reduction in blood cells), lupus erythematosus (an allergic condition that causes skin rashes), or kidney problems.
Do not consume penicitin capsule if you have ever had thrombocytopenia (a blood disorder that causes bleeding into your skin, bruising, and more bleeding than usual after an injury).Penicitin 250mg Capsule 10's is also prescribed for a rare kidney condition called cystinuria in adults and children. Moreover, it is indicated for the treatment of chronic active hepatitis, a type of long-standing liver inflammation in adults.
Uses
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Relieve pain and stiffness caused by rheumatoid arthritis.
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Treats lead poisoning
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Treats Still’s disease in children
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Treats Wilson’s disease
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Treats cystinuria
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Chronic active hepatitis
How Penicitin 250mg Capsule works
As a chelating agent, Penicitin 250mg Capsule chelates mercury, lead, copper, iron, and probably other heavy metals to form stable, soluble complexes that are readily excreted in the urine. In cystinuria, it lowers excess cystine excretion. It also inhibits the production of tropocollagen cross-links and cleaves them when newly created. The method of action in rheumatoid arthritis is uncertain; however, it appears to reduce disease activity.
Interaction of Penicitin 250mg Capsule with other drugs
Inform your healthcare provider about all the medicines that you take, including prescription, over-the-counter, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Penicitin 250mg Capsule and reduce its effectiveness by causing undesirable side effects.
Storage conditions
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Store Penicitin 250mg Capsule at room temperature below 25°C
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Do not freeze
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keep the injection away from the reach of children and pets.
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Do not shake the vials because prolonged shaking may damage the effectiveness of the medicine
How to take Penicitin 250mg Capsule
Take the penicitin 250 mg as prescribed by your doctor. Your doctor will decide the dose and duration of the treatment based on the disease condition and other factors. Swallow the capsules as a whole with a glass of water. Do not break, chew, crush, or dissolve the capsules. Take the capsules on an empty stomach.
Safety Advices
Pregnancy
Penicitin 250mg Capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Breast Feeding
Breastfeeding is not recommended in patients taking Penicitin 250mg Capsule because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Penicitin 250mg Capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Penicitin 250mg Capsule should be used cautiously in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.
Alcohol
It is unknown whether consuming alcohol is safe during the treatment with Penicitin 250mg Capsule. Inform your doctor if you are a chronic drinker.
Driving
Penicitin 250mg Capsule does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
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Rash
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Diarrhea
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Epigastric pain, loss of appetite
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Loss of taste
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Nausea, mouth ulcer
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Vomiting
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Decreased bone marrow activity
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Protein in urine
Serious
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Injection site reaction
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Inflammation of the pancreas
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Renal injury
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Liver problems
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Muscle weakness
Expert Tips
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If you miss a dose, take it as soon as you remember — unless it’s almost time for your next dose.
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Do not take a double dose to make up for a missed one.
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Do not stop or change your treatment without talking to your doctor.
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Do not take Jollimine 250mg if you are pregnant or breastfeeding.
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Your doctor may do regular blood and urine tests to check how well the treatment is working.
FAQs
Q1.
When can I expect Penicitin 250mg Capsule to start working?
The time it takes for Penicitin 250mg Capsule to demonstrate its therapeutic effects can vary depending on the individual and the treatment condition. Following the prescribed treatment plan and having regular follow-up appointments with your healthcare provider to monitor the progress is important.
Q2.
Can Penicitin 250mg Capsule cause allergic reactions?
Yes, Penicitin 250mg Capsule can potentially cause allergic reactions in some individuals. It is important to inform your healthcare provider if you have a history of allergic reactions to medications or if you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing while taking this medicine.
Q3.
What are the common side effects of Penicitin 250mg Capsule?
The common side effects of Penicitin 250mg Capsule are rash, diarrhea, epigastric pain, loss of appetite, loss of taste, nausea, mouth ulcer, vomiting, decreased bone marrow activity, and protein in the urine.
Q4.
When will Jollimine 250mg start to work?
The response to Penicitin 250mg Capsule can vary from person to person. Some individuals may start to see improvements in their symptoms within a few weeks, while others may require a longer time to notice a difference. If you did not find any benefit from the medicine, inform your physician and get medical advice.
Fact Box
|
Molecule name |
Penicillamine |
|
Pharmacological class |
Chelators; DMARDS |
|
Therapeutic class |
Chelating agents |
|
Indications |
1. Relieve pain and stiffness caused by rheumatoid arthritis. 2. Treats lead poisoning 3. Treats Still’s disease in children 4. Treats Wilson’s disease 5. Treats cystinuria 6. Chronic active hepatitis |
References
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Michael C. Byrns and Trevor M. Penning, Environmental Toxicology: Carcinogens and Heavy Metals, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1297-1315.
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Gerard Laboratories, EMC, [Revised on October 2021] [Accessed on June 2023] https://www.medicines.org.uk/emc/product/2713/smpc
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 11 Apr 2026 | 08:46 AM (IST)

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