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Jollimine 250mg Capsule

Prescription Required

Salt Composition : Penicillamine


Origin of Medicine : India

MRP: 173.24
Price :165
You Save :8 (5%)

10 Capsule(s) In A Strip

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Introduction to Jollimine 250mg Capsule

Jollimine 250mg capsule contains the active substance penicillamine. Primarily it is a chelating agent, which means it can bind to certain metals in your body, including copper and lead, to help remove them from your body. It is used to treat Wilson’s disease and lead poisoning. It also belongs to a group of medicines called DMARDS (disease-modifying antirheumatic drugs). It helps to relieve the pain and stiffness caused by rheumatoid arthritis in adults and children. It also treats still’s diseases in children. 

Jollimine 250mg capsule also treats a kidney problem called cystinuria in adults and children. It is also indicated to treat chronic active hepatitis (a type of liver disease)  in adults. Do not take this medicine if you are allergic to penicillamine or any of the other ingredients of this medicine. Do not take this medicine if you have ever had a reduction in WBC after taking this medicine. Do not take this medicine if you have ever had aplastic anemia (severe reduction in blood cells), lupus erythematosus (an allergic condition that causes skin rashes), or kidney problems. 

Do not consume this medicine if you have ever had thrombocytopenia (a blood disorder that causes bleeding into your skin, bruising, and more bleeding than usual after an injury). Inform your physician if you have protein in your urine, if you are pregnant or breastfeeding, if you have blood in your urine, if you have an active infection, and if you are an elderly patient. Your doctor will recommend you take complete blood and urine tests before initiating the treatment. 

Uses of Jollimine 250mg Capsule

  • Relieve pain and stiffness caused by rheumatoid arthritis.
  • Treats lead poisoning
  • Treats Still’s disease in children
  • Treats Wilson’s disease
  • Treats cystinuria
  • Chronic active hepatitis

Therapeutic Effects of Jollimine 250mg Capsule

As a chelating agent, Jollimine 250mg capsule chelates mercury, lead, copper, iron, and probably other heavy metals to form stable, soluble complexes that are readily excreted in the urine. In cystinuria, it lowers excess cystine excretion. It also inhibits the production of tropocollagen cross-links and cleaves them when newly created. The method of action in rheumatoid arthritis is uncertain; however, it appears to reduce disease activity.

Interaction of Jollimine 250mg Capsule with other drugs

Inform your healthcare provider about all the medicines that you take, including prescription, over-the-counter, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Jollimine 250mg capsule and reduce its effectiveness by causing undesirable side effects. 

More Information about Jollimine 250mg Capsule

  • Store Jollimine 250mg capsule at room temperature below 25°C
  • Do not freeze
  • keep the injection away from the reach of children and pets.
  • Do not shake the vials because prolonged shaking may damage the effectiveness of the medicine

How to consume Jollimine 250mg Capsule

Take the medicine as prescribed by your doctor. Your doctor will decide the dose and duration of the treatment based on the disease condition and other factors. Swallow the capsules as a whole with a glass of water. Do not break, chew, crush, or dissolve the capsules. Take the capsules on an empty stomach.  

Safety Advices for Jollimine 250mg Capsule

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Jollimine 250mg capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. 

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Breast Feeding


Breastfeeding is not recommended in patients taking Jollimine 250mg capsule because the medicine passes into the breast milk in small amounts and may harm your baby.

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It is unknown whether Jollimine 250mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Jollimine 250mg capsule should be used cautiously in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.

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It is unknown whether consuming alcohol is safe during the treatment with Jollimine 250mg capsule. Inform your doctor if you are a chronic drinker. 

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Jollimine 250mg capsule does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.

Side Effects of Jollimine 250mg Capsule

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.


  • Rash
  • Diarrhea
  • Epigastric pain, loss of appetite
  • Loss of taste
  • Nausea, mouth ulcer
  • Vomiting
  • Decreased bone marrow activity
  • Protein in urine


  • Injection site reaction
  • Inflammation of the pancreas
  • Renal injury
  • Liver problems
  • Muscle weakness

Word of Advice

Unless it is almost time for the next dose, take it as soon as you remember, then just carry on as before. Do not take a double dose to make up for a forgotten tablet. Do not stop or change your treatment before talking to your doctor. Do not take Jollimine 250mg capsule if you are pregnant or breastfeeding.  Your doctor may routinely take blood and urine tests to monitor the effectiveness of your treatment. 


Q 1. How long does it take for Jollimine 250mg capsule to show its therapeutic effects?

The time it takes for Jollimine 250mg capsule to demonstrate its therapeutic effects can vary depending on the individual and the treatment condition. Following the prescribed treatment plan and having regular follow-up appointments with your healthcare provider to monitor the progress is important.

Q 2. Can Jollimine 250mg capsule cause allergic reactions?

Yes, Jollimine 250mg capsule can potentially cause allergic reactions in some individuals. It is important to inform your healthcare provider if you have a history of allergic reactions to medications or if you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing while taking this medicine.

Q 3. What are the common side effects of Jollimine 250mg capsule?

The common side effects of Jollimine 250mg capsule are rash, diarrhea, epigastric pain, loss of appetite, loss of taste, nausea, mouth ulcer, vomiting, decreased bone marrow activity, and protein in the urine.

Q 4. How long does it take for Jollimine 250mg capsule to start working?

The response to Jollimine 250mg capsule can vary from person to person. Some individuals may start to see improvements in their symptoms within a few weeks, while others may require a longer time to notice a difference. If you did not find any benefit from the medicine, inform your physician and get medical advice.

Fact Box of Jollimine 250mg Capsule

Molecule name: Penicillamine 

Therapeutic class: Chelating agents

Pharmacological class: Chelators; DMARDS


1. Relieve pain and stiffness caused by rheumatoid arthritis.

2. Treats lead poisoning 

3. Treats Still’s disease in children

4. Treats Wilson’s disease

5. Treats cystinuria

6. Chronic active hepatitis


  1. Michael C. Byrns and Trevor M. Penning, Environmental Toxicology: Carcinogens and Heavy Metals, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1297-1315.
  2. Gerard Laboratories, EMC, [Revised on October 2021] [Accessed on June 2023]


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