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Cofaso-S Forte 3gm Injection
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹350
MRP: ₹1029.38
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Cofaso-S Forte 3gm Injection
Salt Composition
CEFOPERAZONE,SULBACTAMMarketer
UNIFAITH BIOTECH PVT LTD
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₹350
MRP: ₹1,029.38
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Introduction to Cofaso-S Forte 3gm Injection
Cofaso S Forte Injection is a combination antibiotic that contains two active ingredients: Cefoperazone and Sulbactam. Cefoperazone belongs to the third-generation cephalosporin antibiotic class, while Sulbactam is a beta-lactamase inhibitor.
This combination makes the injection highly effective against a wide range of bacterial infections, particularly those caused by bacteria that are resistant to antibiotics. It is commonly prescribed for serious infections, including respiratory tract infections, urinary tract infections, intra-abdominal infections, septicemia, meningitis, skin and soft tissue infections, bone infections, and endometritis.
Do not take Cofaso-S Forte 3gm Injection if you are allergic to cephalosporins, sulbactam, or any similar antibiotics. Inform your doctor about any history of drug allergies before starting this treatment.
Avoid alcohol during treatment and for at least five days after the last dose to prevent a possible disulfiram-like reaction, which can cause flushing, headache, sweating, and an increased heart rate.
Uses of Cofaso-S Forte 3gm Injection
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Respiratory tract infections
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Urinary tract infections
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Intra-abdominal infections
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Septicemia
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Meningitis
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Skin and soft tissue infections
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Bone and joint infections
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Endometritis
(These are the common Cofaso s forte uses, always under a doctor’s supervision.)
How Cofaso-S Forte 3gm Injection Works
The Cofaso-s forte 3gm injection composition includes Cefoperazone and Sulbactam:
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Cefoperazone works by stopping bacteria from forming protective cell walls, leading to bacterial death.
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Sulbactam enhances the effect of Cefoperazone by blocking beta-lactamase enzymes that can make bacteria resistant to antibiotics.
Together, they provide a broader and more effective antibacterial action.
Interaction of Cofaso-S Forte 3gm Injection with other drugs
Before starting treatment, inform your doctor about:
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Prescription medications
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Over-the-counter drugs
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Vitamin and nutritional supplements
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Herbal products
Some drugs may interact with Cofaso S Forte Injection, affecting its effectiveness or increasing side effect risks.
More Information about Cofaso-S Forte 3gm Injection
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Storage: Store at a temperature below 25°C, away from direct sunlight.
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Keep out of reach: Store safely out of the reach of children and pets.
- Packaging note: Always use from the original container supplied by the manufacturer.
How to consume Cofaso-S Forte 3gm Injection
Do not self-administer this injection. It will be given by a healthcare professional as:
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An intravenous (IV) infusion, or
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An intramuscular (IM) injection
Your doctor will determine the dosage and duration based on the severity of your infection, body weight, age, and overall health condition.
Safety Advice for Cofaso-S Forte 3gm Injection
Breast Feeding
Avoid breastfeeding while taking Cofaso-S Forte 3gm Injection as small amounts of the drug may pass into breast milk and could harm the baby.
Alcohol
Strictly avoid alcohol during treatment and for at least five days after the last dose, as it can trigger a severe disulfiram-like reaction causing flushing, headache, sweating, and rapid heartbeat.
Liver
Use Cofaso-S Forte 3gm Injection with caution if you have any liver disorders, as dose adjustments and regular liver function monitoring may be needed to prevent complications.
Lungs
Cofaso-S Forte 3gm injection is safe and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.
Driving
It is generally safe to drive or operate machinery after receiving Cofaso-S Forte 3gm Injection, as it does not impair alertness, vision, or motor skills.
Pregnancy
This injection should be used during pregnancy only if clearly needed and prescribed by your doctor after carefully assessing the risks and benefits.
Side Effects of Cofaso-S Forte 3gm Injection
Like all medicines, Cofaso-S Forte 3gm Injection may cause side effects. However, not everyone experiences them.
Common Cofaso-S forte 3gm injection side effects:
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Nausea and vomiting
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Headache
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Diarrhea
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Allergic skin reactions
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Anemia
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Abnormal liver function test results
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Pain, redness, or swelling at the injection site
Serious Adverse Events:
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Severe allergic reactions (Anaphylaxis)
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Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
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Clostridium difficile-associated diarrhea (CDAD)
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Hepatotoxicity (Liver injury)
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Coagulation disorders (Bleeding tendency)
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Hemolytic anemia
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Neutropenia or leukopenia (Low white blood cells)
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Renal dysfunction (Kidney problems)
Inform your doctor if any side effect worsens or persists.
Quick Tips
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Always complete the full course, even if you feel better midway.
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Avoid alcohol during treatment and for at least 5 days after your last dose.
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Do not skip doses.
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Maintain proper hand hygiene to prevent reinfection.
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Talk to your doctor if you need cofaso-s forte 3gm injection alternatives due to side effects or allergic reactions.
FAQs about Cofaso-S Forte 3gm Injection
Q1.
What are the cofaso-s forte 3gm injection uses?
This injection treats various serious bacterial infections such as respiratory tract infections, urinary tract infections, skin infections, and gynecological infections like endometritis.
Q2.
What are the common cofaso-s forte 3gm injection side effects?
Side effects may include diarrhea, nausea, headache, allergic reactions, liver function changes, and local injection site pain.
Q3.
What is the cofaso-s forte 3gm injection composition?
The active ingredients are Cefoperazone (a third-generation cephalosporin antibiotic) and Sulbactam (a beta-lactamase inhibitor).
Q4.
Are there cofaso-s forte 3gm injection alternatives?
Yes, your doctor may suggest other antibiotic combinations if needed. Always consult your doctor before making any changes.
Fact Box of Cofaso-S Forte 3gm Injection
Molecule name: Cefoperazone + Sulbactam | Therapeutic class: Antibiotics |
Pharmacological class: 1. Cefoperazone- Third-generation cephalosporin 2. Sulbactam- Beta-lactamase inhibitor | Indications: 1. Respiratory Tract Infections 2. Urinary Tract Infections 3. Intra-abdominal Infections 4. Septicemia 5. Meningitis 6. Skin and Soft Tissue Infections 7. Bone and Joint Infections 8. Endometritis |
References
- Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
- Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021],https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
- KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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